Basic Information

Insect: Drosophila acutilabella
Gene Symbol: -
Assembly: GCA_035046005.1
Location: JAWNOK010000024.1:1258270-1260356[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.031 2.4 9.0 0.0 2 23 241 263 240 263 0.96

2 10 7.3 5.7e+02 1.5 0.3 6 23 272 289 272 289 0.89

3 10 0.0008 0.062 14.0 4.0 1 23 295 317 295 317 0.99

4 10 0.091 7.1 7.5 4.2 1 23 326 348 326 348 0.95

5 10 0.00054 0.042 14.5 0.4 2 23 357 379 356 379 0.94

6 10 0.00024 0.019 15.7 0.0 3 23 387 407 386 407 0.96

7 10 0.00085 0.066 13.9 1.3 2 23 416 438 415 438 0.97

8 10 4.6 3.6e+02 2.2 2.2 2 23 447 469 446 469 0.77

9 10 8.4e-07 6.5e-05 23.4 1.1 1 23 475 497 475 497 0.98

10 10 4.9e-06 0.00038 21.0 4.1 1 23 503 526 503 526 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.031	2.4	9.0	0.0	2	23	241	263	240	263	0.96
2	10	7.3	5.7e+02	1.5	0.3	6	23	272	289	272	289	0.89
3	10	0.0008	0.062	14.0	4.0	1	23	295	317	295	317	0.99
4	10	0.091	7.1	7.5	4.2	1	23	326	348	326	348	0.95
5	10	0.00054	0.042	14.5	0.4	2	23	357	379	356	379	0.94
6	10	0.00024	0.019	15.7	0.0	3	23	387	407	386	407	0.96
7	10	0.00085	0.066	13.9	1.3	2	23	416	438	415	438	0.97
8	10	4.6	3.6e+02	2.2	2.2	2	23	447	469	446	469	0.77
9	10	8.4e-07	6.5e-05	23.4	1.1	1	23	475	497	475	497	0.98
10	10	4.9e-06	0.00038	21.0	4.1	1	23	503	526	503	526	0.98

Sequence Information

Coding Sequence: atgtgttttctTTGCAGACAGTGTACGGATGATGCTGTTGGTAACATCAAATTTGATTCCGATGAGGCCACACTGCTTGATCTGAACGCAATCATTGAAAAACACTTTTGGCTGCAgACCAAAGATGCCAGTGGGCACGTGTGCAGTGCTTGCTGGGAACAATTGCTAGCGTTTCACAATTTCTACCAGAGTGTCGAGCAGGCCCACAATGAGCTGCTACAGAACCAAACCAAGTTGATTGTGGAGCAAGAGAATCCTACCATTGCGGAGCAAGTGGACGCGATCAATAATGTTGTAAAGCAGGAGAACTTGCTGGGCGAGAGCGTTGCGGCCACAGTGAAGCGTAGACGCGGACGACCTCGTAAGCAATTGCCACCAGAGGATGCAACAGGTATTAATAGCAGCGAATTTAAAGCCGTGCTAGAACAGATCAATCTCAATGAGATTAAAATTGAGTTTCCCGAGGCGGATCTGAGCATTGCCGATGTGCTTGAGGATCAAGAAGAACAAAATATATCGGACTATCTGCAACAAAGCGCTTGTGACACCGAAGATGatgaaattgttgccattcCCATGACAAAAAGACCAAGAAAGACCAAAAAACGACACTACGCAACGAAAACAAAAGTGATGGTCACTAAGGTGAAAGGCGAAAGCGTTCACAATATGAGAAAATCACAGGAATTCAACGACTACATCAGAGATCACTACAAAGTCCAGTGTCCCATTTGCAATGAACCTTTGGATGGTTTCTccgagctgctgctgcatgccCGCAAAGATCACAATCAGCGTGGTTATGCCGTGTGCTGCAATCGAAAGTTTTGGAAGCGAGGCGTACTTGTTGATCATCTGCGTCGTCATCAGGATCCGGATCTATTCAAGTGCCACATCTGTCAACGCGTTATGGGCCATCGTCGCAGCTTGGAGCTGCATATGCGCATGCATGACATCAAGAAACGTGGCCGACTCTATCAATGCGAGCAGTGCTCAAAAAAATTCTACAGCTCCGTCGTATGTGAGCGCCACAAATTGACACACATTCCCAAGGAGCAGTGGCTTGTGAGCTGCACCAATTGCACCAAAACCTTCCCCAATGAATACCTCATGCAACAACATGTGAAGCTGGTGCATTTGCGAAAGTTCGATAAGATCTGCGATGTTTGTGGCAAGTCGGTGCGTGGCCGTGAGGCCTTGGTACGTCATATGGAGGAGCACACGGGAGCCCCACAGAAGGTTATCAAGTGTCATTTGTGTGAATCAACGTTGACCACAAAATATGGTTTGGCACGGCACATTAAAATGATGCATACTGCGGAAAATCTTCAACCAATTCAATGCGAATATTGCCTTAAAATGTCACCTAGCCTACAGGCTCATCAGCATCACATCAAATACACGCACAATACGGCACGTTCACATCAGTGTCCCATGTGCGAGAAGGCCTTCAAGCGCCCCAATGAGTTACGCGAGCACTTGACAACGCACACGGGTGAGGTATTGTATACCTGTCCACATTGTCCAAAGACCtttaattcaaatgcaaatatgcATGCACATCGcaagaaaatgcatttcaagGAATGGCAGGAgtatcatcatcagcatcattcCCGGCAACGCAACGGTGACACCATTATTTCTGTCAGTGTACGCAAAACCACGGAAAGAACTGCAGCGGCATTAAACCAGGAGACGATCGGTGGAAGCGTTATCGGAGTCGATGGCGATGGAATTGGACTGGAGTGTTGA
Protein Sequence: MCFLCRQCTDDAVGNIKFDSDEATLLDLNAIIEKHFWLQTKDASGHVCSACWEQLLAFHNFYQSVEQAHNELLQNQTKLIVEQENPTIAEQVDAINNVVKQENLLGESVAATVKRRRGRPRKQLPPEDATGINSSEFKAVLEQINLNEIKIEFPEADLSIADVLEDQEEQNISDYLQQSACDTEDDEIVAIPMTKRPRKTKKRHYATKTKVMVTKVKGESVHNMRKSQEFNDYIRDHYKVQCPICNEPLDGFSELLLHARKDHNQRGYAVCCNRKFWKRGVLVDHLRRHQDPDLFKCHICQRVMGHRRSLELHMRMHDIKKRGRLYQCEQCSKKFYSSVVCERHKLTHIPKEQWLVSCTNCTKTFPNEYLMQQHVKLVHLRKFDKICDVCGKSVRGREALVRHMEEHTGAPQKVIKCHLCESTLTTKYGLARHIKMMHTAENLQPIQCEYCLKMSPSLQAHQHHIKYTHNTARSHQCPMCEKAFKRPNELREHLTTHTGEVLYTCPHCPKTFNSNANMHAHRKKMHFKEWQEYHHQHHSRQRNGDTIISVSVRKTTERTAAALNQETIGGSVIGVDGDGIGLEC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00608700;
90% Identity: iTF_00478972;
80% Identity: -