Basic Information

Insect: Drosophila acutilabella
Gene Symbol: -
Assembly: GCA_035046005.1
Location: JAWNOK010000068.1:1655799-1658396[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0035 0.27 12.0 0.4 1 23 220 242 220 242 0.98

2 7 0.00055 0.042 14.5 7.3 1 23 572 594 572 594 0.99

3 7 3.8e-05 0.0029 18.2 0.6 1 23 600 622 600 622 0.97

4 7 0.00044 0.034 14.8 4.6 1 23 628 651 628 651 0.96

5 7 1.2e-06 9.6e-05 22.8 2.6 1 23 657 679 657 679 0.97

6 7 4.9e-06 0.00038 21.0 0.5 1 23 685 707 685 707 0.98

7 7 7.8e-08 6.1e-06 26.6 1.4 1 23 713 735 713 735 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0035	0.27	12.0	0.4	1	23	220	242	220	242	0.98
2	7	0.00055	0.042	14.5	7.3	1	23	572	594	572	594	0.99
3	7	3.8e-05	0.0029	18.2	0.6	1	23	600	622	600	622	0.97
4	7	0.00044	0.034	14.8	4.6	1	23	628	651	628	651	0.96
5	7	1.2e-06	9.6e-05	22.8	2.6	1	23	657	679	657	679	0.97
6	7	4.9e-06	0.00038	21.0	0.5	1	23	685	707	685	707	0.98
7	7	7.8e-08	6.1e-06	26.6	1.4	1	23	713	735	713	735	0.98

Sequence Information

Coding Sequence: ATGGAGCGCAAAGAAGTGGACACACAACAGTTCATCGACCACACGCTGCTGGCGACGGAGCTGATGCACAATAACTTTATGATGGATTTAATAGATCACTCTGGTGTCTTTCCCAAAGCCGATGGACCAACAAATCTCAGCACACCGGGCAATACAGCGAATGGTGGCGAAAATTTTGGAGCGAAGCAAACATTAACGCCAGAACTCAATTTCCATAATACGATCTTTCAATTTGTCAACAAACATGTTGTGGACGAACAGAACCAAACACGCTCCAATCAGGTGTCCACATCACCTGAACGCACGCAGAACACCTTTACCAAGCAGACAGATGTGGAGTTTCTGAACATTAACAGCAATTTCCTTAACCCTGACGCAGCCACAGCGGAAGCTGACAACGATGAGGTGCCACCGCAGATCTCACAGCCGTCATTTCCCGCCATGGCTATTGAGCCCACGGTGCCCATTGATGTATCCACAGGACTGCACGATGATGATCTGCTGTACAGTGTTCACAGTGCATCTACAACAAATGCTCGAAAGGTGTTGCCACACAAGAAACGCATCTCGAGAAAGCTCAAGGGAAATCTGTCCTGCATGGAAAGtgagctggagcagcagcacaaGCATCACGTGCAGGTGCCAGTTGTGGCCACCTACAGCTGTGAGATCTGTGGCTATgctgtgcacacacaaatCGAGTTCTATGCACACCTGAAAGAGCACTATGATCCCAGCAATATGGAGCAGCGCTTGGATGTgcctcaacagcagcagcaacaacaaaagcagaagGAACCGCTGGATATGTGCGGACTGACAGCTCAGGACAAGctgcaacaggaGCAAGCCAAGCTGGATCAGGTGTTCCACGACGTGCAATTGAACTTTGAAAACTTTCACAACATCAGTCACGTGGATGATGATGTTGTGGATGATGTAGACGATGTGGGCGTCAATATGGTCATACATTCTGATGCCATCACCTTGCGCAAGACTGATGATAAACTAACCCCAGTTGGTTCGTCTAATGGCACCACCTCCAACGATGTGCCCGTCGTGGATGATGTGGAATTTAGTGATACAGAGGACATGCTCGAAGGAATACGCAATGTTGTGGACAAGGTATCCATCGAGGACACATGTGATGAGCTGGTGGACTTAGAGCTAACAACAAGTGGCATGCGTGCTCCTTGGTTCAATAACAACTTCACGGACATCGCCTTTCCAGGTCTATTGCTGCCCGGAGAGCCCCCGCCGCCCTCGAATCCACTGCTCAAAACAAATCACATTGAAGCTGAGCAAATGACGCTCAATTTTCTCAATACTACCAAGCGGGATGGGGATCAGACGGAGCAACCTGCACAGACCAAATTGGAAATGTGCCACAAGAAGAACTACATTGAAGCTATTGCAACAgccacagcggcagcagcagcaacggcagacAACGGGAGCAAAAGCAATGAGCAAACGTTGATGATGGCAGAACCTTCGCGTACTCCGACACCGATTACAGGCTCTTCCATTGAGCAACTGCAGCGTTCTCCTCTGATCATAAGTGATGCCTTTAAGCTGGAAGATGTGGAAGGCACAGCAGCAGTGGACAACATGATACCATCGCCTGCTGCTTATGACAATGACATGTATCCCATGGAAACAGAGGACAAACAGCGAGTGAATGACGGAACCACAAACGGTGCGAAACGAAAGTATCAATGCAGCAAGTGCGACAGAGAATTCAACTCACACAACTCACTGAAATACCATcagcatacacacacccagGAGCGTGCCTTTCAATGCATCGAGTGCGAGCGATCCTTCTACACGAATAGCGCTTTGAAGGTGCACGCACGTACCCATTCCAGCTTAAGGCCCTTCAAGTGTGATCAATGCGATCACAGTTGTCGACAGTGGGGCGATCTCAAGTATCACATCACCTCGAAGCACACCGATGTCAAGGCCCACATGTGTGAATTTTGTGGCAAGAGTTTCTCCCGCCGTTACTCGCTGGTGGTGCATCGAAGGATTCACACCAGTGAACGGAACTATGTCTGTCAGTACTGCCAGAAATCATTTCGGGCCAGTTCGTATTTGGTGGCCCACGTCAAGGTTCACACCGGGGAGAAGCCTTACACTTGCAACATCTGCGGCAAGAAATTTCGAGTTAACAGTGACCTGAAGCGCCATTCTCGCATCCATGATCCAGAAAGGGCACGAAGCACGCCCAAGGGCACAGCAAGTGCACCCAAAAAGCTTAATGATAGCATCGGTGTCATCAACAAGAGCGGCAAACTCACACAAATTGAGGATGACGAAGAAGACGACGATGATGTCAACATTATAAACAAGTCTGATGCCGTTTGCGGCGACAATGATCAGGAAATTTTGGGCTTATAG
Protein Sequence: MERKEVDTQQFIDHTLLATELMHNNFMMDLIDHSGVFPKADGPTNLSTPGNTANGGENFGAKQTLTPELNFHNTIFQFVNKHVVDEQNQTRSNQVSTSPERTQNTFTKQTDVEFLNINSNFLNPDAATAEADNDEVPPQISQPSFPAMAIEPTVPIDVSTGLHDDDLLYSVHSASTTNARKVLPHKKRISRKLKGNLSCMESELEQQHKHHVQVPVVATYSCEICGYAVHTQIEFYAHLKEHYDPSNMEQRLDVPQQQQQQQKQKEPLDMCGLTAQDKLQQEQAKLDQVFHDVQLNFENFHNISHVDDDVVDDVDDVGVNMVIHSDAITLRKTDDKLTPVGSSNGTTSNDVPVVDDVEFSDTEDMLEGIRNVVDKVSIEDTCDELVDLELTTSGMRAPWFNNNFTDIAFPGLLLPGEPPPPSNPLLKTNHIEAEQMTLNFLNTTKRDGDQTEQPAQTKLEMCHKKNYIEAIATATAAAAATADNGSKSNEQTLMMAEPSRTPTPITGSSIEQLQRSPLIISDAFKLEDVEGTAAVDNMIPSPAAYDNDMYPMETEDKQRVNDGTTNGAKRKYQCSKCDREFNSHNSLKYHQHTHTQERAFQCIECERSFYTNSALKVHARTHSSLRPFKCDQCDHSCRQWGDLKYHITSKHTDVKAHMCEFCGKSFSRRYSLVVHRRIHTSERNYVCQYCQKSFRASSYLVAHVKVHTGEKPYTCNICGKKFRVNSDLKRHSRIHDPERARSTPKGTASAPKKLNDSIGVINKSGKLTQIEDDEEDDDDVNIINKSDAVCGDNDQEILGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00478914; iTF_00569167;
90% Identity: iTF_00478914; iTF_00569167;
80% Identity: -