Basic Information

Insect: Drosophila acutilabella
Gene Symbol: PZF1
Assembly: GCA_035046005.1
Location: JAWNOK010000020.1:19155921-19159543[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.07 5.4 7.9 0.2 3 23 305 326 304 326 0.91

2 10 0.00025 0.019 15.6 0.3 6 23 335 352 335 352 0.99

3 10 9.1e-06 0.00071 20.1 0.2 1 23 358 381 358 381 0.98

4 10 0.00035 0.027 15.1 0.8 1 23 393 415 393 415 0.98

5 10 9.1e-05 0.0071 17.0 3.0 1 23 422 445 422 445 0.96

6 10 1.4e-05 0.0011 19.6 1.8 1 23 451 473 451 473 0.96

7 10 0.058 4.5 8.1 0.5 2 23 482 503 481 503 0.96

8 10 4.1e-05 0.0032 18.1 2.8 2 23 509 531 508 531 0.95

9 10 2.3e-07 1.8e-05 25.1 0.7 2 23 538 559 537 559 0.97

10 10 0.0002 0.016 15.9 4.4 1 23 565 588 565 588 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.07	5.4	7.9	0.2	3	23	305	326	304	326	0.91
2	10	0.00025	0.019	15.6	0.3	6	23	335	352	335	352	0.99
3	10	9.1e-06	0.00071	20.1	0.2	1	23	358	381	358	381	0.98
4	10	0.00035	0.027	15.1	0.8	1	23	393	415	393	415	0.98
5	10	9.1e-05	0.0071	17.0	3.0	1	23	422	445	422	445	0.96
6	10	1.4e-05	0.0011	19.6	1.8	1	23	451	473	451	473	0.96
7	10	0.058	4.5	8.1	0.5	2	23	482	503	481	503	0.96
8	10	4.1e-05	0.0032	18.1	2.8	2	23	509	531	508	531	0.95
9	10	2.3e-07	1.8e-05	25.1	0.7	2	23	538	559	537	559	0.97
10	10	0.0002	0.016	15.9	4.4	1	23	565	588	565	588	0.96

Sequence Information

Coding Sequence: ATGCTCTGTCGCTTGTGTTTGAAAAACATAAACGCAAACAATGCCGTCTTTCTGTTTGAAACGGACGAGACATTAGCCGAGTCCTCGTTGCTAAAAATGATAGCAAAATTCCTGCAACTCGAAATAATGCCGGATGACAATATATCGACGAACATCTGTCACGGCTGCTGTGAACATTTGGAAGACTTCAACAACTTCTGGCAGCTGGTGGAACAGAAACAAGGAACTCTCAAAAAGGAATTCCTTAATGTGGACGTCGATTGTGTCAATCTCAAATGGACGGGAGGCGTCGATGTGGACGTAAACATTGATGAGCTGCCACTTGTCGCCGTCGTGGGGGATGATGAGGTGGATGAGATGGACGAGAAGCCACTGGACATACACAATCTTAATCTGCTGGGCAGTGTGCTCGATGTGAACGTGGACAGCGTGGAGGTGTTGAGCCCCAGGACATCCCAAGCATGCCAGCGTCGAAACTTCGAGCAACTTGGAGACGAACTGAATGCAGAACCTAGCCCAGAGACGAGTGCTGATGAGAAGCCTTTTATTGCCAACGACAGCAGTGACAACAGCGAACGAAATTTTTCCAATGAAGATGATGACTCTGTGCCGCTGGTGCAGCTGCAGCACAAAATGAAACCCAAGCGTAAAATTCGTGCCACACGTGGCAAGCAACAGGCATTGACTCTGGCCCAGGAACTGGATCAACTGCTCGGTGAGAGTAGTAACCataccagcaacagcagagtGCGTCGCAGGAAATTAACACCATTAGGAGCGACTGCAGCAGGGCCCTCCGCCACACAAAGGAATGAACTAGAGGCGGCCTTGGAGCGACGTCCCAAGGGCTGCTCCAGGGCACAGCTATCGAAGCGCTACGAGGAGGCTATTGCCAGCTACATGAATGCGGACTGTGATCTCTGTGATTTCAGTGCCAAGTACTTGTCACAGCTGAAGGTACATTTCCTGGAGGTGCATCAGCAGGACGCGTATCTCAAGTGCTGCAATAAGATCTTCAACCGACCCTCCAAGCTCATGGATCACATACGCAAGCACATCAATCCCAAGCTCTTCACCTGCGAGATCTGCAACAAATCGTTGAACTCCCAGGATTATCTGGCTACACACATAGAAACGGTGCACAACAAGGTCGCTCAGGTGGGCAAAGTGCTCAAGTATCCGTGTGGCAAGTGTGAGAGAACTTTTAGCAGTGAACGTCGCTTGTCCAATCATGTGCTCAAACACGACACGAATCAGTTGGAGCACAGTTGTCAGATCTGCGAGAAGAGCTTTGCCAACGTGCACCGCTTGAGGCGTCACATTCAATCCATACACGAGGATTTGCATCCGCATGTCTGCGATATTTGTGGCAAGAAGTTCAAATTTAAACCTTCCTTCGAGCGTCATCTGCTGGAGCACCAAGGAGTCGTTGCACCAGCCATGGAGTGTCCCATCTGCGGTGTCTGGCTGAAGAACGAGCATAGTCTGCGTTTGCATCGATTTACCCACGATAGTACCGATACCGTGTGTCCGCACTGCTCCAAGACGTGTAGTTCACGCACCGCATTGCGAGCTCACATCAAATATGCGCACAAATTGACAACGACGCTGCAGTGCACGTACTGTGAGAAGACTTTTAAGCAGCAACGGAATCTCGAGGAGCACATGGCCATACACACGGGACTGCAGCTCTACAACTGTCCACACTGTCCCAAGGAGTGTCGTTCCCGTTCcaatatgtatgtgcacatcAAGCAGCGACATGCGGATGAATGGCTCAAGGCTAAAATGGCACGATCGCATAATCCACAGTTTAAGCCATTGGCCTAG
Protein Sequence: MLCRLCLKNINANNAVFLFETDETLAESSLLKMIAKFLQLEIMPDDNISTNICHGCCEHLEDFNNFWQLVEQKQGTLKKEFLNVDVDCVNLKWTGGVDVDVNIDELPLVAVVGDDEVDEMDEKPLDIHNLNLLGSVLDVNVDSVEVLSPRTSQACQRRNFEQLGDELNAEPSPETSADEKPFIANDSSDNSERNFSNEDDDSVPLVQLQHKMKPKRKIRATRGKQQALTLAQELDQLLGESSNHTSNSRVRRRKLTPLGATAAGPSATQRNELEAALERRPKGCSRAQLSKRYEEAIASYMNADCDLCDFSAKYLSQLKVHFLEVHQQDAYLKCCNKIFNRPSKLMDHIRKHINPKLFTCEICNKSLNSQDYLATHIETVHNKVAQVGKVLKYPCGKCERTFSSERRLSNHVLKHDTNQLEHSCQICEKSFANVHRLRRHIQSIHEDLHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECPICGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHIKYAHKLTTTLQCTYCEKTFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00478897;
80% Identity: -