Basic Information

Insect: Drosophila acutilabella
Gene Symbol: hang
Assembly: GCA_035046005.1
Location: JAWNOK010000020.1:24961641-24980198[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.38 30 5.6 1.0 3 23 525 546 524 546 0.93

2 18 0.28 22 6.0 3.5 3 22 653 672 651 672 0.89

3 18 0.00083 0.064 14.0 3.3 1 22 785 806 785 808 0.90

4 18 0.095 7.4 7.5 0.1 2 21 820 839 819 840 0.93

5 18 0.00096 0.075 13.8 0.2 2 23 958 980 957 980 0.95

6 18 0.0028 0.22 12.3 0.1 1 23 988 1011 988 1011 0.96

7 18 2.2e-05 0.0017 18.9 0.1 2 23 1097 1118 1096 1118 0.97

8 18 0.0004 0.031 15.0 2.9 2 23 1224 1246 1223 1246 0.97

9 18 0.031 2.4 9.0 0.2 2 23 1255 1277 1254 1277 0.95

10 18 0.0017 0.13 13.0 0.1 1 23 1290 1313 1290 1313 0.97

11 18 0.00017 0.013 16.1 1.1 1 23 1376 1398 1376 1398 0.99

12 18 0.0027 0.21 12.3 0.9 1 23 1406 1429 1406 1429 0.96

13 18 0.094 7.3 7.5 0.4 2 19 1437 1454 1437 1455 0.94

14 18 3.6e-05 0.0028 18.2 0.4 3 23 1563 1583 1562 1583 0.98

15 18 0.007 0.54 11.0 0.1 1 23 1618 1640 1618 1640 0.97

16 18 0.00082 0.064 14.0 0.6 2 23 1743 1765 1742 1765 0.93

17 18 0.015 1.2 10.0 0.4 3 23 1821 1841 1821 1841 0.98

18 18 9.3e-05 0.0073 16.9 2.1 1 23 2286 2308 2286 2308 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.38	30	5.6	1.0	3	23	525	546	524	546	0.93
2	18	0.28	22	6.0	3.5	3	22	653	672	651	672	0.89
3	18	0.00083	0.064	14.0	3.3	1	22	785	806	785	808	0.90
4	18	0.095	7.4	7.5	0.1	2	21	820	839	819	840	0.93
5	18	0.00096	0.075	13.8	0.2	2	23	958	980	957	980	0.95
6	18	0.0028	0.22	12.3	0.1	1	23	988	1011	988	1011	0.96
7	18	2.2e-05	0.0017	18.9	0.1	2	23	1097	1118	1096	1118	0.97
8	18	0.0004	0.031	15.0	2.9	2	23	1224	1246	1223	1246	0.97
9	18	0.031	2.4	9.0	0.2	2	23	1255	1277	1254	1277	0.95
10	18	0.0017	0.13	13.0	0.1	1	23	1290	1313	1290	1313	0.97
11	18	0.00017	0.013	16.1	1.1	1	23	1376	1398	1376	1398	0.99
12	18	0.0027	0.21	12.3	0.9	1	23	1406	1429	1406	1429	0.96
13	18	0.094	7.3	7.5	0.4	2	19	1437	1454	1437	1455	0.94
14	18	3.6e-05	0.0028	18.2	0.4	3	23	1563	1583	1562	1583	0.98
15	18	0.007	0.54	11.0	0.1	1	23	1618	1640	1618	1640	0.97
16	18	0.00082	0.064	14.0	0.6	2	23	1743	1765	1742	1765	0.93
17	18	0.015	1.2	10.0	0.4	3	23	1821	1841	1821	1841	0.98
18	18	9.3e-05	0.0073	16.9	2.1	1	23	2286	2308	2286	2308	0.99

Sequence Information

Coding Sequence: atgtgcGACGCTgccgcaacaacaatagcagcaggAGGAGCTGGAACCAGTGCTAGTGCTAGCGCTGGAACTGGAACGGGTGACACAGCGACATCAATGGATGAACAAGCTCAGCGTACGCGACAAAATTGTTGTCGCCTGTGCCTTGCGCCCGCCACCGAATGCATTTCGATCATTAACAGTTATGCAGCCGATAAGGAGTCGTTGGCTACAAAAATACATAACTGCGTAAATATCAAGATCACACCACTGGATCGCCTGTCGCTGTACATTTGCCACGCCTGCATCAGTTACTTGAACTCTTGGCAGAGTTTCAAAAATCGCTGCTTGAGCTCACAAACAAAGCAGCGCCACTGGCTGGACACGGAGGGCAGTAAACAGCAGACACTATTGGGCTATTTGGATTTAAATCGAGCCGAGAATGGCAGCACAACACAAGccgagcaacagcagcaatccGAATTGAAAAATGATGTgtcgacgacaacaacagcagcagctgagaaGACAACGGCTGCAAACATTTTGGATGGCATACCATCGCTCAAGAAGCGCAAATCTTTAACAGTTTATGTGAGTCCCAAGCAACagcttcaacaacaacaacaacaacagcaccaacaacaacagcaactgcaccagcagcagcaacaacaacagcaattacaGCTGCATACGGATGCGCAGCATACTTTGCAGAATCTTTTATTGCAGGTCCCAACAACGGCAGcgacaatggcaacaatagcaacacaacagcagcaccagcagcaacgcaaatatcagcaacagcagcagcaacatcaacgtGGCAAGCAGTCACAttaccatcatcatcatcagcaacatcaacagcagcaacaccttTCACAGCGTTATAGACGCATACGACAGCCCCGACGACAgttgccagcagcaacagcaaccacagcgtcagcaactgttgctgttgtgccacAACGTTTACCCAAATTCAAGCCAAAAGTTTATTTACCACTTGATATTGCAGTGCCCCCGCTGCCGCCTCAACTGGCCATACCGATgtcagcaactgttgctgctgccagtgctgttacagcaacagcaactgctgctgcttcgactgctgctgctgttactgctgctgagATATTGCCATTGTCGCAGCCAATTGATTTCAGCCATTGTAAGATTTCAAATCAAAGTCAAagatttgacagcgttttaaCACcgccgtcgcagtcgcagtcgctgccaacgtccattgctgctgctactgctactacgTCTAGCGTCGCTGGCGCAGCTACAACGCCGCTGCTGATGCCGCCGCTGCCCGCTGTGCCCATCAAGGATGAGCCACTCGATGACACGGACGATGACTTTCAGATGAAGTGCATTGACGAGTCCGATGACATGATGGACCCCACTATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGATTATGACTACACGGCGCAGCACGGCGTAACAGCTGCGGTGGCAGCCGCATCGTTGCCTCCGACCGCAGTGGCGAATGTGGCCGCCGCTGGAGACTCAAAAGTGGCCAGTTGCCGTGCATGCAGCTTACAGTTCTCCACACGCGCCAATGCCCGACGACACGAGCGTAATCTGCATCCAAATCTATTTCAACTATCAACAGATTCACCCAACAATACGCCCATAACAAAACCGACACCGGCACTGGCAGCAGCACTGGAGATACAACGTGCCgctgccgcagcagcagcaacggcagagGCAACCAAAGCGGCAGCTGGTGGAAATATATCGACACAAAAGTATCGACAGGTTGTGATGAACACGTTCATCAAGTGTGAAAACGGTGGCTATGACTATGAGCAACCGGAACAGTATCAGCAGCTATTGAGTCGCGACAAAGTCGAGTTCATACAGGAGAATAATGAATTTCTGGAACAATATCAGACAATGACGTGTCGCTGCTGTAATAAATTCTTTAGCACCTACAAGAACTTCATGGCACATGTGCGTAAGAAGTATCCAACGCTACCGCGAAATCTCTGCTTCAATTGCCTCAAAATGAACGACTCGAAGGCTTTGTTCATTTCGCATCTGAAGAAACGCAACTGCATCAATTTGTATCGTGTTTTGAATGCACTGCGTGTGAAGCAACCCAATTTTGCACATGCTACTGCTACGGGTTTGGTAGCCACCACCGAGACGGTAGCAACAGCTGCACCAGCAACacccaagcagcagcagcagcagcaacaacagttgctggCATCACAGCAACCGCTGGTGGAAACGCCCAACACTTTGGAGCGACCGGAGAAACTACGCGCCAAGGAGTTGCTCGTGAATAAACTCTATGAATGCAAATTGTGCCCCAAAGGATTTCGTACCAAACACGAGTTTCGCACCCATGTGTACGATAAGCATGCGGATGTGCAGCGCAAGGATAACAACTCTATACAGTGTAGCTTCTGTGGCTTGGATTTTGCTGATCCTGTGGATCGACGACGTCATTATAATAACATGGATTGCATTGTGCGTCTGCGTTGCATGACCTGTGATGCCAAATTGGAGACACATCAACGTTTCCTCGACCATGTCTATCAGGATCATTTGGGTGGTGTGAGCAGCGACAATGCCTCCACTACAGCGAACAGTGCCATCGATCAGCACTCGCCGGGCAAACGCAGTTTATTGGGTGCTTTGGGCATTGGTGTCAGTCAATCATCGAACGATGAGTCCCGCAGCAGTGGCAGTAACAATCATCCACTTACCTCTACGCCCAAGCTACCAGTGGCGGCCGTGCCAAGCAGCGGTACTCCAGCGAGTCGCACTGAAGCACCCAAATCACAGTATTTCTCGCGTATGCCGCAGGTTTGTCCCATCTGTGGACAACAGtacaacaactataacaatgTCTTGCGTCACATGGAATCAAAGCATCCCAATAAACTGCCCGAGACATATAAATGTGTGCGCTGTGGCTTGGGTTATCCACGAATTTCGTATCTACGCGAGCATATGATCAATGTTCATGGTGTGGACAAGAATCGTCATTCGGGTGGATTTGAGTACATTGTGAATGCGGATGCAGTGAAGCTAGCGGATGGCAGCACTCCAAATGTCTATACGGGACGCTATGACTATGTGATGAAGGATTTGATGTCCATAACAAATGGTGGGACACTCGATGACGACGATGAGGAAGGCGGAAGCATTGCCAAAAAGATGCGACTCgatgacagcagcaacaacagcagcatcaacaccAGCATTGCCAATCAACAAAAAGAGTGTCCCATATGCAATGCGGTGTTTAGCAACAACATTGGACTATCCAATCACATGAGATCACATTACACGGCCTCATCGACGGCCACGAATGCAGCATTGGCAGCAGCAAATCGCATGACACCAAAATCGTTGACAATCACAGCAACACCGCCAATCGAGctagcaacagttgctgcaacagcaacaacaacagcggcagcagcaacagctgcagccacagcgacagcagcaaccgcaacaacagcagcagcagcagcaacaacagcgacaacagttGCTGCCAAAGTACCACCAGCAATGGTAAATCAGACACCGCAGGAACAAGCCGTTTTCCGACGTAGTTTGGATCAAGCTGCCGATCGTCGCTTTCGTCGCATGCGTTGTCGCATTTGCCAGCGTCGATTCAGTTCAAAGAAATCGTATCGTTATCACATGTTAACCGATCATCAGGTGCAGAATGTGCAGTTTatcaaatgtaaattatgcaatgCTGAATTTGCCTACGAGAAGGGATTGAAGGTGCATTTGTTCAAGGTGCATGGACGTGCCATCAAGGATGAAATGATAATTAAGCAATTTGAATGTGATATCTGTTCGATAGTCTATAGTTCGGAATTGGAATTGCAACAGCACAAACGTAGCGTGCAcaaatcagcagcaacaacagcagcagcaacatctgcagcaacatcaacaacaacattgaaatCATCgacaacagctacagctaccTCGTCCTCGGCCTcagcctctgctgctgcctctgtctctgccaCTGCAGCTGATCTGGCCGATATATCGGGCAGCGCTTTGGCCGTCTTGCCGCTGTATTGGTACCAGTGCAAGTATTGTCCATCCAATTTCAATACAAACAAGAAACTGGCCATTCACATCAATTCGCACGATGAGTTCGATTCGAATGATTATTCGTGCAAGGATTGCGGCAATGTCTACAGTGGTCGCAAGAGTCTTTGGGTGCATCGTTACAAGAAGCATCCACAGGTGCCCGATCCGGCAGAGTGCACGCTCTGCCGTAAAATGTTCTTTGATCGCCAAATGCTGGAGAATCACACGCCGACCTGCAATCGCAAGCCCATAACGGCAACGGGAGCACACCAGCAggaccagcagcaacagcagcagcaacaacaacaacaacagcagcagcaacagctgcaactacaacaacagcaacgtggCATCTTTAAACACAAAACCGGAGACGATGATGAAGAGGAAGAAGATGAtgagcatcaacaacaacaacagtcgctcttagatgatgctgctgctggcaccgATGGCAGCaatggtgctgctgctggtagcggcagcaacaacacacaacacacattcAGTACAAGCAATCTAAAGATACGCATACCCGAAGTGGCATGCACCATTTGTGGTGCACGTTTCACCGATCAGGAAATGTTCACCAAACACATACAGAAACACGAACAGGAATTGTATGTGGACAATCCATTGGCAGCAATGTTCGATGATGGACCCGCAGATGCGGGACAATTTCAGGTGGAACGGCAGAACGAGAATGGGGAATATGCATGCGATTTGTGTGCCAAGACATTCCCACAGGTGATCGCACTCAAGGTGCATCGCAAATGGCATTTCAGAGGTGATAGCAAGCAGAATCACATCATCGACGGCGAAGCGACAATgctgaacaacaacaacaccaacaacaacagcagcagcaacaacaacaacaacagcagcagcaacaattcgATGTTGCAACTGCGCGAATTGCATGCTGTGGGTTTGATGCCCAACCAGCAACaccagaagcagcagcagcaacaacaacagcaacagtcgagcagcagcaacaacagcagcagcaacaacaacaacaacagcagctcaacgacaacaacaacgacgaacAAATCGTTGAAACGTAAACGTGAATTGAAATGTGAATATTGCGCCTCCACCTTCATCAGCAACAATAATCTGCGTCGTCACATGTATGAATTGCATAAACATGAAGTTAGTAATTTACCTGAACCGCCAGTGATTGAAGTTGATGAACCGCTGTGCTGTCGTCGCTGCGGTGATATTAAATTTGAGACGAAAGAGCTGTGGATCGAACATAAATTGGCCGATGCTAAAGTTGTTCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTTTGTGGCGAGTATTTGTCACGCAAGGAGAAGCTGTTAAATCACATCAACAATCACCTGAAAGAGGAGGTGATTGTGCCAGTTGCTACTGTCAAGACGGCAGCGAAAACTACAACAGTTGCTGcggtaacaacagcaacaaccgctgcgacaacagcagcaacaaaagcaactacaacaacagcagtagcagcagcagcagctaccacagcaacaacaactgttgctcCCATTAAGACTTTGAGAGTTAAACAGTTGGCTATGGAAAATGATGTGGAAAAGGAGCAGAAACCGcagcaggagcaacagcaagaaGAGGTAGATGATAGCGATATGGCTGATGATAGTGATAgtgacgacgatgatgatgatgatgataccACAACAGCagatgatgacgatgaagacgacgatgatgatgaggtgGAGGATGAGGAGGCAGAGGTGgctgcacagcagcaacaacaacagcaattgctgcaaaacaacaatagcaacagcaacaacaatcgaaacagcagcaacaacagcagcagcaatgccaTGGAAAacgatgttgatgatgatgatgacgatgatctGATTGAAGAGGTTATCGAAGAGATtgatgaagatgaagatgtGGTTGAGCAACAACAgacacaacgacaacaacaacatgttgttgctgttgccgctgctaacaacaataaagtgAATTTTGTGAATGGAAATCGCAAGAAAACGAAAGTTGAACAAATTCTTGTGATGCACAGCtctgacgatgatgatgatgatgtcgacgatgatgttgatgatgatgatgatgatgagatGGAAATGGGTGATGTTGATGAGGATGTGGGTGTGGTTGGTGAAGTGATGACCATTGATGATATTATAGAGGAAGATGATGGTGAAGATGATGATGTGCTTGGTGTTGATGGTggtaatgttgttgttgaagatgatgatgaagatgatgataacgacgatgacgatgacaatgataatgatgatgacgatgatgtaGAAGAAGACGCTGACGAAGAGGAAGATGaagatgttgatgatgatgaggagaATGTGCGTGTACATGCCGTtgcagatgatgatgatgatgatgaggatgaggatgatgatgatgaagatgatgagcGTGGTCATGGGCGTGGTCGTGTCAACATCAATGACACCGATGGCGATGtcgatgctgatgctgatggtGATGGAGACGCTGATGTTGATAATGATGTTGATAatacatcatcatcaacatcatcgtCCGAGAGCGAgtcaacgacaacaacaacaatgtcgCAGTCAACTGGTGAGCGgcgtaaaaataaaaaatcaattgttCAATCATCGGCGGCACTTGGCGCTGCCGCTGATCAGTCTAATTCCAGTTATACGTGTGATCTATGTCAACTTTGTTTTGATTCTCAGGAGCTACTGCAGACACACATTAAAAGTCATTTCCTCAATGGGCCAAAGGCGGGCAACaaggccaacagcagcagcagcagcagcaacaacaaccatagCAGCGGCAAcatcggcagcagcagcagcagcagcaacaacaataacaataatcataataaaagcaaaaccaaaaagtcCAGCTTGTTGGAGGCAAACAAGAgtggcagtgggcgtggcagtgcaactgcaacaaacacaacagcaactgttgcagcggcaactacaacaacgacgacagcggaggcagcggcagcaactgcgacagcagcagcgacagatgCTGCAGCCAGCTTGAACTGA
Protein Sequence: MCDAAATTIAAGGAGTSASASAGTGTGDTATSMDEQAQRTRQNCCRLCLAPATECISIINSYAADKESLATKIHNCVNIKITPLDRLSLYICHACISYLNSWQSFKNRCLSSQTKQRHWLDTEGSKQQTLLGYLDLNRAENGSTTQAEQQQQSELKNDVSTTTTAAAEKTTAANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQHQQQQQLHQQQQQQQQLQLHTDAQHTLQNLLLQVPTTAATMATIATQQQHQQQRKYQQQQQQHQRGKQSHYHHHHQQHQQQQHLSQRYRRIRQPRRQLPAATATTASATVAVVPQRLPKFKPKVYLPLDIAVPPLPPQLAIPMSATVAAASAVTATATAAASTAAAVTAAEILPLSQPIDFSHCKISNQSQRFDSVLTPPSQSQSLPTSIAAATATTSSVAGAATTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAAVAAASLPPTAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISTQKYRQVVMNTFIKCENGGYDYEQPEQYQQLLSRDKVEFIQENNEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYPTLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRVKQPNFAHATATGLVATTETVATAAPATPKQQQQQQQQLLASQQPLVETPNTLERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTTANSAIDQHSPGKRSLLGALGIGVSQSSNDESRSSGSNNHPLTSTPKLPVAAVPSSGTPASRTEAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEEGGSIAKKMRLDDSSNNSSINTSIANQQKECPICNAVFSNNIGLSNHMRSHYTASSTATNAALAAANRMTPKSLTITATPPIELATVAATATTTAAAATAAATATAATATTAAAAATTATTVAAKVPPAMVNQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKSAATTAAATSAATSTTTLKSSTTATATSSSASASAAASVSATAADLADISGSALAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQQQLQLQQQQRGIFKHKTGDDDEEEEDDEHQQQQQSLLDDAAAGTDGSNGAAAGSGSNNTQHTFSTSNLKIRIPEVACTICGARFTDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNHIIDGEATMLNNNNTNNNSSSNNNNNSSSNNSMLQLRELHAVGLMPNQQHQKQQQQQQQQQSSSSNNSSSNNNNNSSSTTTTTTNKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLCCRRCGDIKFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLLNHINNHLKEEVIVPVATVKTAAKTTTVAAVTTATTAATTAATKATTTTAVAAAAATTATTTVAPIKTLRVKQLAMENDVEKEQKPQQEQQQEEVDDSDMADDSDSDDDDDDDDTTTADDDDEDDDDDEVEDEEAEVAAQQQQQQQLLQNNNSNSNNNRNSSNNSSSNAMENDVDDDDDDDLIEEVIEEIDEDEDVVEQQQTQRQQQHVVAVAAANNNKVNFVNGNRKKTKVEQILVMHSSDDDDDDVDDDVDDDDDDEMEMGDVDEDVGVVGEVMTIDDIIEEDDGEDDDVLGVDGGNVVVEDDDEDDDNDDDDDNDNDDDDDVEEDADEEEDEDVDDDEENVRVHAVADDDDDDEDEDDDDEDDERGHGRGRVNINDTDGDVDADADGDGDADVDNDVDNTSSSTSSSESESTTTTTMSQSTGERRKNKKSIVQSSAALGAAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPKAGNKANSSSSSSNNNHSSGNIGSSSSSSNNNNNNHNKSKTKKSSLLEANKSGSGRGSATATNTTATVAAATTTTTTAEAAAATATAAATDAAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00569122;
90% Identity: iTF_00569122;
80% Identity: -