Dqua024049.1
Basic Information
- Insect
- Dromius quadrimaculatus
- Gene Symbol
- topi
- Assembly
- GCA_963989225.1
- Location
- OZ022328.1:124627-126704[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00066 0.12 14.8 1.9 3 21 113 131 112 132 0.95 2 13 8.4e-05 0.015 17.6 3.4 1 21 157 177 157 179 0.94 3 13 0.018 3.2 10.3 0.6 3 23 187 207 186 207 0.95 4 13 0.11 21 7.7 0.2 2 21 226 245 225 246 0.92 5 13 0.00011 0.02 17.2 0.9 1 23 277 299 277 299 0.99 6 13 0.42 77 5.9 3.9 2 22 342 362 341 365 0.86 7 13 0.37 68 6.1 0.1 1 23 447 470 447 470 0.96 8 13 0.11 19 7.8 1.0 1 23 474 496 474 496 0.93 9 13 7.8e-07 0.00014 24.0 2.4 1 23 502 524 502 524 0.98 10 13 0.027 4.9 9.7 0.2 1 23 530 555 530 555 0.96 11 13 0.25 45 6.7 3.3 1 23 561 583 561 583 0.86 12 13 9.5e-06 0.0017 20.6 0.5 3 23 591 611 589 611 0.98 13 13 2.8e-06 0.00051 22.2 0.5 1 23 617 640 617 640 0.98
Sequence Information
- Coding Sequence
- ATGAGCTTTGAAGACAATACTTTATTGAAAGTGATTCGAATAGTCAGTTCTGGTGATGGTCAGGAAGAAATAGATCCATCAAATAAGGTAATTTCTGACTCAAATATAAATTGGGACAATTCCAATGGAATTAAATGTGATTTAAATTACAACCGTTTTGCTAAAGATGAGTTTCCTAatgtaacaataataaaaatagtgaaTATAGACGAATTGAACTCAATGAATTTTATTGCACAAGTAAATGCTATTACAAATACGGAGAATTATATTTTCTCCGAGACGAAAAAGCAGCAAGAAAGGCGAGTAAATCTTCCAGACacaagtacaattttgtgccaAAATTGTGATACTtcatttccaacaaaatatcaatatcaacgTCATCAGTGCGAATTTAATGCCGAAAAAGTTGTACTCAAACCAGAAATCGCTGGTAAAGATTTGGATAAAGCTACTAGATTAAGATTCGAATGTGATGTTTGCAAAAAGTCGTTtgttagtaataataatttggagCGGCACAAAAATTGCCACAAAAATGGAGATAGCAATATTTGTGAGTTTTGTAATAAGATATTTGTGAGTGAAAATCGGCTGAAAATTCATAAAGAGAATCACTGCAAGAAAGCGGGGGATACTACTAAATTTTATAGGAGTGATGTTGCAGTTTGGCGCTGTGAAAGATGCAAACAAGTATTTGCTACAAGCGAAAGCGGAAATAAACATATTAAACAATGCACAACAGTTGAAACaacaaatgaaattaatattaaaagtaTATTTGATTCTAATGCGACTTTAGAAAGAATTATAACTGAAATGTTGTATCAATGCGAATTTTGTAACCGGACTTATGCTGAAAAATCAGCGGTACTCAACCACCAAAAAACTCACACAACTGAAAAAAATTACGAATGCATTTTTTGCGACCAACATTTTATTAGTTACTGTCAAGCCACTGTTCATTGGCAAAGCAAATGCAATAacgaatcaaatttattttatctgccAAAACTGATATATTGCGAACATTGCGACCGTGGTTTCAAATCCCACGAAATATTATACAaccataaaaacaaaaaaaagcatTTTACTCCcaaaatttttaacaaagtTGAAGAAAAAACTGATGAAGATATTAAATCAGAAAACGAACAAGCAATTgccaaaatgattgaaaatatgattgctaaattggatcaaaaagaaaatattttagtggCAGTTAAAGAAGAATTTAATTCAGAAAATGGGAAGAAAAAACGTGGCCGCAAGAGGAAATggcaaaaaactgaaataaaaaataaatttgaggcTGATGAAGGTTGCCAATATCAATGCGAAAGGTGTGCAGCTGCTTTTGACACAATTATCTCATTGGATACACATAAAGAAACTACCCATGCAAGCACTTACAGATGTGAACAATGTGGAcagATTGTACACAGCGCAAAAGCTCTTATGATTCATTGTCGAGCCCACCAAAGCCTCAAGCCTTACGTGTGCGACCAATGTGGTCGTAGTTACTCCCAAACATCCCACCTTTGGCAACACATGAGATTCCATCAAGgTATCAAACCTTTTGCCTGTCCCCATGAAGGCTGCGAAGCTCGCTACACCATCCGCCCTGATTTAAAAGACCACATTCGTAAAGTACATACACGAGAACGACCTTTCAAATGTTCTGTCTGCAACAAATGCTTTTTAACTGGATCTGTTTATTATCAACATCGCTTAATTCACACCAACGATCGCAGATATGGATGTGAAATCTGCAACAAACGCTTTTTCCGGGCGGACGCCTTGAATAACCACAGAAGAATTCATACAGACGAACGTCCTTATCCATGCCCAGTTTGTGGAAGGCAATTTAGACAAAAAGGAGATAGAAATAAACATGTCCGCACCCAACactccctataa
- Protein Sequence
- MSFEDNTLLKVIRIVSSGDGQEEIDPSNKVISDSNINWDNSNGIKCDLNYNRFAKDEFPNVTIIKIVNIDELNSMNFIAQVNAITNTENYIFSETKKQQERRVNLPDTSTILCQNCDTSFPTKYQYQRHQCEFNAEKVVLKPEIAGKDLDKATRLRFECDVCKKSFVSNNNLERHKNCHKNGDSNICEFCNKIFVSENRLKIHKENHCKKAGDTTKFYRSDVAVWRCERCKQVFATSESGNKHIKQCTTVETTNEINIKSIFDSNATLERIITEMLYQCEFCNRTYAEKSAVLNHQKTHTTEKNYECIFCDQHFISYCQATVHWQSKCNNESNLFYLPKLIYCEHCDRGFKSHEILYNHKNKKKHFTPKIFNKVEEKTDEDIKSENEQAIAKMIENMIAKLDQKENILVAVKEEFNSENGKKKRGRKRKWQKTEIKNKFEADEGCQYQCERCAAAFDTIISLDTHKETTHASTYRCEQCGQIVHSAKALMIHCRAHQSLKPYVCDQCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCNKCFLTGSVYYQHRLIHTNDRRYGCEICNKRFFRADALNNHRRIHTDERPYPCPVCGRQFRQKGDRNKHVRTQHSL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -