Basic Information

Gene Symbol
-
Assembly
GCA_945859695.1
Location
CAMAOO010000072.1:1648293-1652103[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00029 0.018 15.6 2.6 1 23 247 269 247 269 0.98
2 10 1.8 1.1e+02 3.7 0.1 3 23 293 314 291 314 0.92
3 10 0.0025 0.16 12.6 4.7 2 23 337 358 336 358 0.95
4 10 0.081 5 7.9 1.6 2 23 363 384 362 384 0.96
5 10 0.0016 0.096 13.3 3.6 1 23 391 414 391 414 0.93
6 10 0.00051 0.031 14.8 0.8 1 23 420 443 420 443 0.94
7 10 1.1e-05 0.00066 20.1 2.0 1 23 449 472 449 472 0.97
8 10 2.9e-05 0.0018 18.7 1.7 1 23 478 500 478 500 0.98
9 10 3.9e-07 2.4e-05 24.6 0.7 1 23 506 528 506 528 0.98
10 10 5.2e-06 0.00032 21.1 1.3 1 23 534 557 534 557 0.98

Sequence Information

Coding Sequence
ATGAGCACAGTGAAAGGCAAAGGACCCATAGTGGACCCTGGCGAGTGTCGGTGCTGCGGCGGGCGCAAGAAGTGCCGTCTGATGAACGTACAGTACGAGTGGTGCGGGCAACCTGAGGTCTACTCCGATATGTTTGTGGATTGCTTTGGTTTGCTGCTTTCTCACTTAGATGGTGATGTTGAGGAGCGCCTGATCTGTGCGACGTGTGTTACTCGACTGCGGGAGGCGTGTGCCTTCCGGAGACAAGTGCTGCAGTGCGAGGAAAGGCTGTTGCACACTGCAATACATGTGCATGGAGATGGCTTAACCAATAGTGAAGTCAAAGAGGAGCCATTGAAGGTGGAATTGGAAGATGGTCCGTCACAAGAAGACCATGTTGATGGTGACCAAGATGGTGGCGCCGAGCACATTGATGATGATCTCGATAGTTCAATGGAGGAGCCATTGAGCTTAGCAGCTAAGAAGCTAACGAAACGCAGAAAGGTTCTCACTAAAGGTGCCGCAAAGAAGAGGAGTAAAGCGAAGTCGCTCAGGGAATGTTTGGAGAAGAAATCCAAAGTGAGAACACTGCGGAGAAGGAATGTCGAGTTGGAGAATATTAATGTACCATATGACGACCCGGCCCATCCACCGGCCCGGCCGAAGTTATTATTAGACAGcgagcacaaggcattcatgaacacagtcaccattgtggagaactcctatgtgtgtcccttcgacacgtctttcagcgattactactgcctctactgcagggaagtgttcaccgacccttgcaagttgagggagcacaccctcacccacgaccctgccaccttcaaaacccacctgaacaacaagaaactaccccaagttgacatctttcgcatcgactgccgcctctgcccgaagaggatcgacgacatcgaactactcaaaggccacctgtccaatttccacggattgaaactgcacttggatatgtcgaatgaattcctcaagtttcgtttgacgctcaccacgttgacttgtacggaatgcagttgctcatttagcttcttccacgcgctcaagaaacacatggccgagcactttggcacgtgcatttgcgacgtgtgcggcgctcattacttcgaggaacggatgctggtgctccaccagaaaactcatcagcgcgtcgacgagtactttccgtgtagggagtgcggtaagagcttcaagtcgaagcacagtaggtatttgcacacggctcgaacccacaacaaggagccggcgtaccagtgcagcaaatgcgatgaggtcttcttctcctattctctcaggtataggcatatgattgcagtccacggggaacacagaatgtttccttgcgagcattgcgatagagcgtacgacagcaggaagtctttacgagagcatatcaggcgattccacctgaagattttcaagcatcagtgcgatttgtgcgataagaggttctatttgccgtcgaggttgaaggagcatatggctactcacacgggagagaggaactttagatgtgagtactgcgggaaaagctaccctcggcttagaggccttaaggtccatatgcagtcgcatagtagtgagaagaagtatagatgcgtcctgtgcagcgctacgtttactcagaatgtgaatttgaagaatcatatgaagaggcagcatcagagtttagagatggaagATGGGTTTCGGGAATAG
Protein Sequence
MSTVKGKGPIVDPGECRCCGGRKKCRLMNVQYEWCGQPEVYSDMFVDCFGLLLSHLDGDVEERLICATCVTRLREACAFRRQVLQCEERLLHTAIHVHGDGLTNSEVKEEPLKVELEDGPSQEDHVDGDQDGGAEHIDDDLDSSMEEPLSLAAKKLTKRRKVLTKGAAKKRSKAKSLRECLEKKSKVRTLRRRNVELENINVPYDDPAHPPARPKLLLDSEHKAFMNTVTIVENSYVCPFDTSFSDYYCLYCREVFTDPCKLREHTLTHDPATFKTHLNNKKLPQVDIFRIDCRLCPKRIDDIELLKGHLSNFHGLKLHLDMSNEFLKFRLTLTTLTCTECSCSFSFFHALKKHMAEHFGTCICDVCGAHYFEERMLVLHQKTHQRVDEYFPCRECGKSFKSKHSRYLHTARTHNKEPAYQCSKCDEVFFSYSLRYRHMIAVHGEHRMFPCEHCDRAYDSRKSLREHIRRFHLKIFKHQCDLCDKRFYLPSRLKEHMATHTGERNFRCEYCGKSYPRLRGLKVHMQSHSSEKKYRCVLCSATFTQNVNLKNHMKRQHQSLEMEDGFRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00724167;
90% Identity
iTF_00467620;
80% Identity
-