Dpar000450.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dorcus parallelipipedus
Gene Symbol
topi
Assembly
GCA_958336345.1
Location
OY284475.1:2223106-2227825[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.014 1.3 11.1 0.1 1 23 117 139 117 139 0.98
2 21 0.018 1.6 10.7 0.1 1 23 143 165 143 165 0.98
3 21 0.02 1.8 10.6 2.9 1 23 199 224 199 224 0.96
4 21 0.016 1.5 10.8 0.2 1 23 230 253 230 253 0.92
5 21 5.2e-05 0.0048 18.7 1.0 1 23 260 282 260 282 0.99
6 21 0.63 58 5.9 0.2 2 23 287 307 286 307 0.87
7 21 0.0089 0.82 11.7 2.2 1 23 313 335 313 335 0.96
8 21 1.9e-07 1.8e-05 26.3 4.0 1 23 341 363 341 363 0.98
9 21 0.00056 0.051 15.5 0.2 1 23 438 460 438 460 0.96
10 21 0.0035 0.32 12.9 0.3 1 23 464 486 464 486 0.98
11 21 0.014 1.3 11.0 1.7 1 23 492 514 492 514 0.98
12 21 0.01 0.93 11.5 0.2 1 23 580 602 580 602 0.98
13 21 0.00064 0.059 15.3 0.3 1 23 606 628 606 628 0.98
14 21 0.0074 0.68 11.9 0.4 1 23 634 656 634 656 0.98
15 21 0.026 2.4 10.2 2.1 1 23 662 687 662 687 0.96
16 21 0.00047 0.043 15.7 2.0 1 23 693 716 693 716 0.97
17 21 0.00053 0.049 15.5 1.4 1 23 723 745 723 745 0.99
18 21 3 2.8e+02 3.7 0.6 2 23 750 770 749 770 0.92
19 21 0.00023 0.021 16.7 0.5 1 23 776 798 776 798 0.98
20 21 1.1e-06 0.0001 24.0 2.4 1 23 804 826 804 826 0.98
21 21 0.00027 0.025 16.4 1.4 1 21 832 852 832 853 0.95

Sequence Information

Coding Sequence
ATGTCGATTGGCCAGGTCCGGAACAAAAACCCCACGCCAAATTTTCTGAATGATGGCAAGCGGACTCCTCGAATTACTTCGAATGGCCCTAGGGGGATCAAATCTTCTGGAATTCGTTCGAAGGAACCAAGCCTCGATGCGCATGAGAAGGTTGCTGTGGGTGGCAACACCAACTCGCGACGTAGTAGGGTTAGGAAGCTTCAAGATGAGTACGTCAAACGTTTCCTGTGCGAACTATGCAGCAAACCCGAACTGATGACGTTGAAAGAACTGAATCGACATTACCTTACGCACGGTCAGACAGGTCTGAGAAAATTTCGCCATCGCCGGTCCAAACCTGATCAGCTGTTCACTTGCGAAATCTGCTCGGCGAATCTGAATTCTATAACCGACCTGCAGAGGCACGTGGAAACTCACGAAGATCAATATTCTTGCGACGCGTGTAAAAGAGGTTTCAAGCAGATTATAGACTACATAATCCACGTGAGAATTCACAGCGACGAGGATGTTTTTAGGTGCGCCCTCTGTGACTATCGTAACGGGAGCGCGTCGAGGATGAGAAGACACGTTCTGTGCCACGACAGGTTCAAGAACTATCGCTGTGAAGTCGAGGGCTGCAACCGGACCTTCACGATCTCCACTCACTTCGAGGAGCACAAGAAGTACTTTCACACGGGCGAGAAATCGTACATTTGCGACGTCTGCGGTCAACGGTTCATGTACGAGCGTGTTCTAAACCGGCACAAAGTGGTCAATCACGACGTAGGTCCAAAGCAGTACAAGTGCAAAAAATGCGGCGAGGTATTCGCAAGTTACAACCTGCGCCGAAATCACATGAACGTCCACAAGCAAGGCGTCGTGTGCGGGACATGCGGGAAAACGATCAGCACGCCGTACTTTAAAGTCCACGAGCGGATGCACACCGGCGAGAGGCCTTACGAGTGTAAGCATTGTGGGAAGGCGTTTCCCTGTCGGATGGTGCTTGCCCAACACGTGCAGACACACACCGGCTACAAGCCGCACAAGTGCGATATTTGCGGGAAGTGTTTCACGCAGAGGTCAAGCTTGGTGATACACATGCGATTGCACACCGGGGAGAAACCCTACACgGTACGATCATTCAGGCTTGTATTGAATCCGGAATTTTCAAACGACGCCTGTGGTGAgctcaaaaatattaataatgcAAATTACTTATGGAAAGAAATCACCAACGAAGAATATCAAGCTGGCGCGGAGGCGTATTTGAAAGGCCGTAGATATCGTAAAAATCCTGAAGGCCTGAAGAAGCTCCAGGAACCTGGCAGGTCGTTCGTCTGTGAAATCTGCTCCCGGAAGTTTTCTTCGCAGGAAACCCTAGACGGTCACATTGTAAGCCACGATGAACATTACGTATGTGAAGTTTGCGAAAAGGGTTTTAAGAAAGTCATGGATTACACCATGCACGTGCAGTCACATCGCGATGATAAATTGTATAAATGCCCCCTGTGCGACTACAACACCCCCAAGGCCCACCACATCGAATCACACTTGCTCTCGCACCAAGTCAACAAGAAATGCGAGTCACGACCTAAGAAAATCAGAAAGCTTCCAGATGAGTCCGTCAAGCGCTTCCTGTGCGAATTGTGCAGCGAACCTGAATTAATGACACTGACGGAATTGAACCGACATTACCTCACGCACGATCAAAGGGGCCTGAAGAAATACAGATATCGCCGGCGTAAAGAGGGCCAGTTGTTTCCGTGTGAAATCTGTTCGGAAAATCTAGATTCTTTGGTCGATCTACACAGACACTTGGAGACCCACGAGGACCAATACAGCTGCGACGTCTGCAAAAGGGGTTTCAAGCAGATTATAGACTATATTATGCACATGAAAATCCACACCGACGATAAACTTTTTAGATGCGCCCTCTGTGATTACTCGACCGAGAACGCTTCGAAGATGAAGAGTCACGTTCTAAGCCACGATAGATTCAGGAGTTATCGATGCGAAGTGCAAGGCTGCAATATGGCCTTCACCGTATCTACTCACTTCGAAGAGCACAAAAAGTATTTTCATACCGGCGAGAAATCATTCGTCTGCGACGTCTGCGGCCAAAAGTTCGTATACGAGCGAATGCTAAACCGACACAAGGAGACCTGTCACAACGTAGGATCCAAACGGTACAAGTGCAGAAAATGCGGCGAGGTATTCGCCAGCTTCAAGGAGCGTCGTAATCACCTGAAGGTCCACCAGGACGGCATCGTGTGCGGAACGTGCGGAAAGAAGGTGGGCATCATGCACTTCAAGGTGCACGAGCGAATGCACACGGGCGAGCGACCTTTTAAGTGTGAGCACTGCGGGAAGGCGTTCCCCTCTAAACCCATACTTTTACAACATGAGCGAATCCACACCGGATATAGGCCGTACAAGTGCGAGATCTGTGAGAGGTGTTTTACGCAAAGGTCGAGCTTAGTGAGGCACGTACGAGgacataccggcgagaaacccTTCTCGTGCCACTTTTGCAGCAAAGGTTTCGTTTCTAAGTCCGCTCTTACGACACACGTAAAAAATTGTACGGGCTAG
Protein Sequence
MSIGQVRNKNPTPNFLNDGKRTPRITSNGPRGIKSSGIRSKEPSLDAHEKVAVGGNTNSRRSRVRKLQDEYVKRFLCELCSKPELMTLKELNRHYLTHGQTGLRKFRHRRSKPDQLFTCEICSANLNSITDLQRHVETHEDQYSCDACKRGFKQIIDYIIHVRIHSDEDVFRCALCDYRNGSASRMRRHVLCHDRFKNYRCEVEGCNRTFTISTHFEEHKKYFHTGEKSYICDVCGQRFMYERVLNRHKVVNHDVGPKQYKCKKCGEVFASYNLRRNHMNVHKQGVVCGTCGKTISTPYFKVHERMHTGERPYECKHCGKAFPCRMVLAQHVQTHTGYKPHKCDICGKCFTQRSSLVIHMRLHTGEKPYTVRSFRLVLNPEFSNDACGELKNINNANYLWKEITNEEYQAGAEAYLKGRRYRKNPEGLKKLQEPGRSFVCEICSRKFSSQETLDGHIVSHDEHYVCEVCEKGFKKVMDYTMHVQSHRDDKLYKCPLCDYNTPKAHHIESHLLSHQVNKKCESRPKKIRKLPDESVKRFLCELCSEPELMTLTELNRHYLTHDQRGLKKYRYRRRKEGQLFPCEICSENLDSLVDLHRHLETHEDQYSCDVCKRGFKQIIDYIMHMKIHTDDKLFRCALCDYSTENASKMKSHVLSHDRFRSYRCEVQGCNMAFTVSTHFEEHKKYFHTGEKSFVCDVCGQKFVYERMLNRHKETCHNVGSKRYKCRKCGEVFASFKERRNHLKVHQDGIVCGTCGKKVGIMHFKVHERMHTGERPFKCEHCGKAFPSKPILLQHERIHTGYRPYKCEICERCFTQRSSLVRHVRGHTGEKPFSCHFCSKGFVSKSALTTHVKNCTG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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