Basic Information

Insect: Dorcus parallelipipedus
Gene Symbol: topi
Assembly: GCA_958336345.1
Location: OY284475.1:1331845-1336041[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.21 19 7.4 0.0 1 23 95 117 95 117 0.96

2 27 0.02 1.9 10.6 1.2 1 23 121 143 121 143 0.95

3 27 0.56 52 6.0 0.5 1 23 149 171 149 171 0.86

4 27 0.015 1.4 10.9 1.0 1 23 177 201 177 201 0.96

5 27 0.00036 0.033 16.1 2.2 1 23 207 230 207 230 0.96

6 27 0.0005 0.046 15.6 2.6 1 23 236 258 236 258 0.98

7 27 0.064 5.9 9.0 1.7 1 23 263 282 263 282 0.77

8 27 2.8e-05 0.0026 19.5 2.2 1 23 288 310 288 310 0.98

9 27 1.8 1.7e+02 4.4 2.3 1 23 355 377 355 377 0.97

10 27 0.0038 0.35 12.8 1.6 1 23 383 405 383 405 0.98

11 27 0.0013 0.12 14.3 0.3 1 23 411 433 411 433 0.99

12 27 0.015 1.4 11.0 2.7 1 23 439 461 439 461 0.98

13 27 0.0034 0.31 13.0 7.8 1 23 467 489 467 489 0.98

14 27 5.9e-05 0.0055 18.5 0.7 1 23 495 517 495 517 0.98

15 27 0.0038 0.35 12.8 1.8 1 23 521 543 521 543 0.98

16 27 0.0055 0.51 12.3 1.3 1 23 549 572 549 572 0.96

17 27 0.061 5.6 9.0 0.3 2 23 579 600 578 600 0.96

18 27 8.3e-06 0.00076 21.2 2.4 2 23 629 650 628 650 0.97

19 27 0.003 0.28 13.1 5.1 1 23 656 678 656 678 0.98

20 27 2.8e-07 2.6e-05 25.8 1.7 1 23 684 706 684 706 0.99

21 27 0.53 49 6.1 0.6 2 23 713 735 712 735 0.90

22 27 0.00021 0.019 16.8 1.9 1 23 740 762 740 762 0.97

23 27 0.001 0.093 14.6 1.0 1 23 772 795 772 795 0.97

24 27 0.00011 0.011 17.6 0.1 1 23 803 825 803 825 0.97

25 27 7.2e-07 6.6e-05 24.5 0.5 2 23 832 853 831 853 0.98

26 27 1.5e-05 0.0014 20.4 1.0 1 23 859 881 859 881 0.98

27 27 0.089 8.2 8.5 1.0 1 23 887 910 887 910 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.21	19	7.4	0.0	1	23	95	117	95	117	0.96
2	27	0.02	1.9	10.6	1.2	1	23	121	143	121	143	0.95
3	27	0.56	52	6.0	0.5	1	23	149	171	149	171	0.86
4	27	0.015	1.4	10.9	1.0	1	23	177	201	177	201	0.96
5	27	0.00036	0.033	16.1	2.2	1	23	207	230	207	230	0.96
6	27	0.0005	0.046	15.6	2.6	1	23	236	258	236	258	0.98
7	27	0.064	5.9	9.0	1.7	1	23	263	282	263	282	0.77
8	27	2.8e-05	0.0026	19.5	2.2	1	23	288	310	288	310	0.98
9	27	1.8	1.7e+02	4.4	2.3	1	23	355	377	355	377	0.97
10	27	0.0038	0.35	12.8	1.6	1	23	383	405	383	405	0.98
11	27	0.0013	0.12	14.3	0.3	1	23	411	433	411	433	0.99
12	27	0.015	1.4	11.0	2.7	1	23	439	461	439	461	0.98
13	27	0.0034	0.31	13.0	7.8	1	23	467	489	467	489	0.98
14	27	5.9e-05	0.0055	18.5	0.7	1	23	495	517	495	517	0.98
15	27	0.0038	0.35	12.8	1.8	1	23	521	543	521	543	0.98
16	27	0.0055	0.51	12.3	1.3	1	23	549	572	549	572	0.96
17	27	0.061	5.6	9.0	0.3	2	23	579	600	578	600	0.96
18	27	8.3e-06	0.00076	21.2	2.4	2	23	629	650	628	650	0.97
19	27	0.003	0.28	13.1	5.1	1	23	656	678	656	678	0.98
20	27	2.8e-07	2.6e-05	25.8	1.7	1	23	684	706	684	706	0.99
21	27	0.53	49	6.1	0.6	2	23	713	735	712	735	0.90
22	27	0.00021	0.019	16.8	1.9	1	23	740	762	740	762	0.97
23	27	0.001	0.093	14.6	1.0	1	23	772	795	772	795	0.97
24	27	0.00011	0.011	17.6	0.1	1	23	803	825	803	825	0.97
25	27	7.2e-07	6.6e-05	24.5	0.5	2	23	832	853	831	853	0.98
26	27	1.5e-05	0.0014	20.4	1.0	1	23	859	881	859	881	0.98
27	27	0.089	8.2	8.5	1.0	1	23	887	910	887	910	0.97

Sequence Information

Coding Sequence: ATGAGGATatttaaaaaaagcagCAAAAAGCGACCGAGAAACGAAAGCGAAGGCGACGGCATCAACTTGCCCCTGGAAGTGATCATAAAAGTCGAAGCCGATAAGGAGGCGGCCAATTCGAATTTGCCCCGAAAAGGCAAAATCAAACGGAAGAAGCAAGACGCAATGAAAACGTATACCTGCACGATATGTTCTGTGAGCGCGAGGATGACGAAGAGAGAAATGAATGCGCACTATAGAACTCACAGGGGTAAGAAGTCGCACGAGAAACCGAACAGGATGTTCGTGTGTGACATTTGCTTGGAGAACCTACCCTCCGCCGAAGCCCTAGAGGATCATATAGAAGAACACGAGGACCAATACAAGTGCAAGATCTGCCAGAGGGGGTTCAAGAAGATACTGGATTACACGTACCACGTACAGGCCCACAGCGACGATAAGCTTTACAGGTGTCCGATATGTGACTACACCATGCCAAGCCGACATAGAGTTAGGCCTCACATTGCAACGCACAACTTCTTCAAAAAGTACGAGTGCCCCATCGATGGCTGCAAGAAGGGCTTCACGGTGCTAACCCACTACGAGGAGCACAAGAACTTCCACACCGGCGAAAAACCGTTCGTCTGCGAAATCTGCGGGACGTCTTTCATGTACTCGCACTACCTCACCATACACAGGACCAAGCAGCACAAGCCGGAGAGGCAGTACAAGTGTTCGGTTTGTTCGGAGACCTTCACCGGTTTTAAGAACCTCAGGACGCACAAGCTACGCCACGAACGGTCGGACCACATCTGCAAGATTTGCGGCAAAAGCTATAAGCAACTGAACTCGCACGAGCTGACGCACACCGACCATAAGCCGCACAAGTGCAACTATTGCGAGAAAACCTTCAGGCTGAAGGGGAATTTGGTTGACCACGAACGGATTCACACCGGTTGTAGGCCGTACAGTTGCACGGTaaAGTACTTCGCTCACGTGGAAGGTAACGAGGAAATCCCCGAAGTAAAACCACAATCACCCCTCCAGGAACTGCCCACGTCACTCCGATCCAAAGACAAGGCGTACAACTGCGATTCCTGCAATTTTAAAACGACCATGTCCGACCGTTTTAAACTGCACTTAATAAAACATGCAGCCGAAAAGCCTTACGCTTGTAACTTTTGCGATTATAAGAGCAGATTCCGTTCGAATTTAGGCGTGCACTTGAAACGacacaccggcgaaaagccgTTCAAGTGCGCCACGTGCGATTACGAAGCCACCGAATCTGCGAAGCTCAGGAGACACATGATAACACActccgacgagaaaccgtttcAATGCGGCACGTGTGAGTTTAGATGCAAGGACGCGGTGCGCTTGAAATCGCACATGTTGAGGCACACCACCGAAACGCCGTTCCAGTGCGAATCGTGCGACTACAAATGTAAAACGTCTTCTTGCTTAAAGAGGCACCTCTTGAAACACACCAGCGGAGGGCTGTTTAGGTGTGGGGAGTGCGATGCGAAATTCACCGAGCCCGCGCACTTGAAGCAGCACGTGTCGACACACGGCGGGCGGTTTAAGTGTAAGAAGTGTGATTTTAAAACTGCCGAATCTAAGTCGTTGAAGGAGCACGTGCTGACGCACGCCGGCGATCGGCCTTTCAAGTGCCCGATTTGCGGTTTTAAGGCGAGTAAATTCAAAACCTTGAAGAACCACGTCAAGTGGAGGCATACGGGTAGGGAACTCATCAAGTGCAACCTCTGCGATCATAAGGTGGTCCGACCTAGGGATTTGAAGCCCCATATGGTAGTACATACCGGTGAGAGACCTTATCAATGTAATCTTTGCGACTGCAGGCAAGAGGATCTCGCCCCCGCAAAACCATCGAAAAACGTCAGCCAGTGTCACGTTTGTTCGAAGACTTTCGCCCGCTGGCGCCTCCTAAAGCGTCACCTGGTGACACACACCAGCGAAAGGCCTTTCAAATGCGACCTCTGCTCGAAGCACTTCCGGCGCAACTTCGAGATGCTCGCGCACAGGAAATACCACAGCGACGCCAAACCCTTCAAGTGCGATGTGTGCGATAAGTCGTTCAAACGGAAGGGCGCTCTCGAGAACCACCGGAAGAGACACGTGAAGGATTACAAAGTTGTGTGCGAGGTTTGCCAGGTCGGCTTCTATTCGAACTGCGAGTACAAGCTCCACCTCGGCTATAAGCACGGGCAGGGCAAGTTTATTTGCGAAATTTGCGCCAAGTCCTTCTACAATAAGTTCGGACTCAATCAGCACATGCACCTGCACCGGGAGTGCTACAAGGACGAAAGGAAATACACGTGCGACATATGCAATAAGGGATTCTTGCGGCCGATTTATTTGAGGGCGCACCACAACAAAGTGCACAAGGACAGTTCGAGGAAGCACTACGTTTGTGATTTGTGCGGGAAGGAGGTTTCTTCGAGTACTAGTTTGAGGGAACATCAGCTGCTACACGAGGGCGTTAAACCCAATAAGTGCGACGTGTGCGAGAAGAGCTTCGCGTCCAGGTCGAATCTCGTCGTGCACTTGCGGACGCACACCGGTGAAAAGCCGTACGAATGTCGGGACTGTGGCAAGTCGTTTACTCAGAGGAACACTTTCGTCATACACGCGCGTCAACATTCCGGGGAACGTCCTTATATTTGTCAGTTGTGCCGTGAAGGTTTCATCAGCAAAAATATGTTGAATTTCCATCTTAGGAGCAAACATAATATACTTAAGATGAACAGTCTCAAATAA
Protein Sequence: MRIFKKSSKKRPRNESEGDGINLPLEVIIKVEADKEAANSNLPRKGKIKRKKQDAMKTYTCTICSVSARMTKREMNAHYRTHRGKKSHEKPNRMFVCDICLENLPSAEALEDHIEEHEDQYKCKICQRGFKKILDYTYHVQAHSDDKLYRCPICDYTMPSRHRVRPHIATHNFFKKYECPIDGCKKGFTVLTHYEEHKNFHTGEKPFVCEICGTSFMYSHYLTIHRTKQHKPERQYKCSVCSETFTGFKNLRTHKLRHERSDHICKICGKSYKQLNSHELTHTDHKPHKCNYCEKTFRLKGNLVDHERIHTGCRPYSCTVKYFAHVEGNEEIPEVKPQSPLQELPTSLRSKDKAYNCDSCNFKTTMSDRFKLHLIKHAAEKPYACNFCDYKSRFRSNLGVHLKRHTGEKPFKCATCDYEATESAKLRRHMITHSDEKPFQCGTCEFRCKDAVRLKSHMLRHTTETPFQCESCDYKCKTSSCLKRHLLKHTSGGLFRCGECDAKFTEPAHLKQHVSTHGGRFKCKKCDFKTAESKSLKEHVLTHAGDRPFKCPICGFKASKFKTLKNHVKWRHTGRELIKCNLCDHKVVRPRDLKPHMVVHTGERPYQCNLCDCRQEDLAPAKPSKNVSQCHVCSKTFARWRLLKRHLVTHTSERPFKCDLCSKHFRRNFEMLAHRKYHSDAKPFKCDVCDKSFKRKGALENHRKRHVKDYKVVCEVCQVGFYSNCEYKLHLGYKHGQGKFICEICAKSFYNKFGLNQHMHLHRECYKDERKYTCDICNKGFLRPIYLRAHHNKVHKDSSRKHYVCDLCGKEVSSSTSLREHQLLHEGVKPNKCDVCEKSFASRSNLVVHLRTHTGEKPYECRDCGKSFTQRNTFVIHARQHSGERPYICQLCREGFISKNMLNFHLRSKHNILKMNSLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -