Basic Information

Insect: Dorcus hopei
Gene Symbol: -
Assembly: GCA_033060865.1
Location: CM065426.1:41436521-41437750[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.05 5.5 9.1 6.2 1 23 110 133 110 133 0.91

2 8 5.1e-06 0.00057 21.7 0.8 1 23 137 159 137 159 0.97

3 8 0.00026 0.029 16.3 3.6 1 23 165 187 165 187 0.95

4 8 6.2e-06 0.00068 21.4 0.5 1 23 193 215 193 215 0.98

5 8 0.0015 0.16 13.9 0.7 1 23 221 244 221 244 0.96

6 8 1e-05 0.0011 20.8 4.4 1 23 253 275 253 275 0.98

7 8 1.7e-06 0.00019 23.2 3.0 1 23 281 303 281 303 0.97

8 8 0.0002 0.023 16.6 1.9 1 23 309 332 309 332 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.05	5.5	9.1	6.2	1	23	110	133	110	133	0.91
2	8	5.1e-06	0.00057	21.7	0.8	1	23	137	159	137	159	0.97
3	8	0.00026	0.029	16.3	3.6	1	23	165	187	165	187	0.95
4	8	6.2e-06	0.00068	21.4	0.5	1	23	193	215	193	215	0.98
5	8	0.0015	0.16	13.9	0.7	1	23	221	244	221	244	0.96
6	8	1e-05	0.0011	20.8	4.4	1	23	253	275	253	275	0.98
7	8	1.7e-06	0.00019	23.2	3.0	1	23	281	303	281	303	0.97
8	8	0.0002	0.023	16.6	1.9	1	23	309	332	309	332	0.96

Sequence Information

Coding Sequence: ATGACGGAAAACAACCTAACGGACAAAGTAACATGCAGAACGTGCTTGTCGCTCATCGACAAAAGATCGACCGTGTCAATTTACGATGTCTCCGAAATGATAATGCTTTGCAGCTCGATAAAGATTCTAGAGCTCGACGGCCTTCCCCCTCACATTTGCAGAAGTTGCCATAACATGGCAGAGAATGCTTACAAGTTTCGCCTACTCTGCGAACAATCTGACAGAAAGTTACGGGCGAGTTTAACCCCTCAACTTAACGTTGAGATTATCTTGAAGGATGAGTCTGATAGTATATCGGAGAAAAGTAGTATAGAAGAATCAAACCAATTTAATTGCAAAGTTTGTTGTAAATCATTTTCCAATGAAACTCAACTTAAACAACATGAATCTCATAATCATGATGTCACATTTAATTGTAACGAGTGTGGTAAAGCATGTGCAAATCCTCGTTACCTAGCGAAGCACATGAGTTTGCATCGTCCGAGGACTCCTTTTTTGTGTAATACATGTGGAAAGCAGTTCACATGCAAGAGTAACCTCATAAAGCATGAGAAGATTCACAGTGGATTAAAGCCATTCGAATGCACGGTGTGCAACAAGCGATTCATTGAATCCAGAGATCTGAAAGGCCACATGATCACACACAGTCAAGAAAAATCATATCTCTGCAATTACTGCGGGGATAAACTAGCAAGAAAAAACGCTCTGCGAATGCACATAAGAAGAAAGCATGCCTTGCGCAAGGAACCTCCATCTTATAAGTGTGATTTATGCGGGAAGTGTTTTACAGatagGACTGTTTTGAACAGACACAAGTACACGCATACTGGTGAAAAAAAGCACGTCTGCAATGTATGTCACAAGGCATTCAATCGGCGAAGCAATTTATCAGTACACGAGCGAATACACAGCAACCTTCGGCCTTTCATCTGTACAATATGTCAGCGAGGATTTAACCAGAAACACGTCTTAAACACCCACATAGAAAAAACTCATCAAGTCAAcacttaa
Protein Sequence: MTENNLTDKVTCRTCLSLIDKRSTVSIYDVSEMIMLCSSIKILELDGLPPHICRSCHNMAENAYKFRLLCEQSDRKLRASLTPQLNVEIILKDESDSISEKSSIEESNQFNCKVCCKSFSNETQLKQHESHNHDVTFNCNECGKACANPRYLAKHMSLHRPRTPFLCNTCGKQFTCKSNLIKHEKIHSGLKPFECTVCNKRFIESRDLKGHMITHSQEKSYLCNYCGDKLARKNALRMHIRRKHALRKEPPSYKCDLCGKCFTDRTVLNRHKYTHTGEKKHVCNVCHKAFNRRSNLSVHERIHSNLRPFICTICQRGFNQKHVLNTHIEKTHQVNT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01258512;
90% Identity: iTF_00466792;
80% Identity: -