Dhop024282.1
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- -
- Assembly
- GCA_033060865.1
- Location
- CM065423.1:43219803-43224089[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00024 0.027 16.4 0.4 1 23 222 244 222 244 0.98 2 10 3.7e-05 0.0041 19.0 1.0 3 23 252 272 250 272 0.98 3 10 6.4e-05 0.0071 18.2 2.3 1 23 278 300 278 300 0.99 4 10 0.25 27 6.9 0.3 1 23 306 328 306 328 0.93 5 10 0.00041 0.045 15.7 1.1 1 23 334 356 334 356 0.95 6 10 5e-05 0.0055 18.6 1.6 1 23 362 384 362 384 0.98 7 10 0.00014 0.015 17.2 4.8 1 23 390 412 390 412 0.98 8 10 8e-05 0.0089 17.9 2.0 1 23 426 448 426 448 0.95 9 10 0.001 0.11 14.4 0.2 2 23 454 475 453 475 0.97 10 10 1.5e-05 0.0017 20.2 0.2 1 23 481 503 481 503 0.97
Sequence Information
- Coding Sequence
- ATGGAAGAGCGCGCAAACATCTTGCGTGCGATGAACATTTGCAGATTTTGTCTAGACGACAAGGGGCCTCTTACCAACATCCACGAAAAGGACGGCGGCAGAGACGCAAAACAATCGGTTCCGCTCCCGCTTCAAATTATGGCCTGCGTTGCGATCGAAGTGTTTCAAAACGATGGTATGCCCCAGCTTATATGCAACACGTGTCGAAGCCACACCAACCAAGCGTACATCTTCAAAACTACTTGCAAGAAATCAGATGATGCACTCAAACTGTTCCTCGCCACTGGGAATATTCAGATATTAAAAGGGTCGGATAAGGATTTTCAAGCGAGCTTAATGGGATCACAGAAAAGAACAATGTCAGATAAAGACCAGCCACTGAAACAGGaatccaaaaaaattaagacgGAGAATGCAGTCGTCATGTTAAACAACACGAAGCCATTGGATGCCGGAAAACTGCTGGAAAGTGCAGAGCATTTTGGAGACGAGGAAAACTCCGAGCATATCATGGAACTAGATGAAGGTGAGAATGTCCACGAGGAAATAATCGAGAATATGTCAGATGAGCCGGAGGATGAAGACGAGGATGATGACGATGATGACGAAGATGAAATGAAAATCAATCCGATACTGAAGGTGCCCCAAGTGCAGACGGATGTTTTCCCTTGTCAGTACTGCGAACGGTCTTTTCCCCTGAAGCAACTGTTAGAATTGCACATTAAGAATCACACGAGGGAACGGAGCTACGGTTGTTCACAGTGTGGCCGAAGGTTTTTTACAAAGTATGATTTGGGCAAGCACATCCAAACTCACTCGGATGCGAGACCGTATACTTGCGTCGTTTGTCAGAAGCAGTTTGCGAGGGAGTCTCTCCTACATCGTCATGAAAAAACACACGTCGATGTGCCTAAGTATTTATGCTCTTCGTGTGATCGAACTTTTTTGAGTCGTGCTGACTTGGATGCCCACTCGGAGAAGCACAAGAAAAAAAGACCGTTTTCATGTCGCATCTGCAAGAAGAGTTTTGTTTTTAAGCAGGGCTTAGAGCGACATGAAGTCTCACACAGCGAGGAGAAACCACATAAATGCAACTATTGCGAGGCAAGCTTTACGTCGCCCATCAAATTGATGAGGCACATAACGTCTCACGCCGGGTTACGACCTTACCCTTGCAAGCTCTGCGGTCGCACGTTTTTGTTAAGCCATCATCTGACGAGGCACATGCGAAGTCACTATGCAGCTAAAAATGCGGAGTCACAACCGATAGGTCAACACAAGTGCGATATTTGCAGCATGTCCTTCAGACGTAAGGACTCTCTCATAAATCACAGCACCATACATTCGATGGTTAATCTAAAGTGTGTAATATGCAATACCGCTTTTGATAATGCCAAGCAAGTAATGAACCATATCACCACGCACTTATCCGGGTTGCCGTATCCATGTGATAAGTGCGATTATTCATTCGATACGCAAGATCAATTGGAAGAGCATGAAATCAAGCACGCTGAGATGGAATACGAGGACCAAATCGAACAGGAAGTCCACCTGGAGGCTACCCAGAACGCTTCAAGTGCAGACAAGGAAGAAGGCGATGATTCCGGGGATGACGTGGCAGAATTCACGATAACAAACCCAGAAAACCCAGAGATCGTGCGCAGGCCAAGGAGggcaacgaaaataaaaaactacgCACAGTTTTTGAAAGAAGAGCTCGGTTCCGATGTAGAAGACGATTTGATCCAAGAAGAAGAACCGTCGGAAATTACACCCGACTTAAACACACCGGAAGAGCAAGCGATCAAACCGATTGTTAGAATCGAAGGCACAAAGGTGTATGCCCGGAAGAATTTAATGGAGAAACCGAGGGTAATCCCGAATGTGAATGTCTCAAGACCACAAACCGCACAGCCCGAGCAGATAAATCAAAGGCTTACTACTTTGGAGAATTTAGGGTTGACGAAACAGGCGGTGAAGGCTTTGCCCAATAAGCAATTCGTCGATATGAAGATCGGTGACAAAACTGTGAGAGTGCAGAAGCTGATGATGACGAAAGCTGAAATCGATGCGATGGCGAAGGAAGGCAAAATAGAAATGAAAGGGGACACGATTCTTTTGAAGAAAGTGCCCGATAAGGCGATGCCATTTCGTCACACCATGGAATCGATTATAGACGACGTGAAACCAATGGTGAATCCGAAACCGGTCGTCAAGAAAACCTACATGAAAAAGATCAACATGGATAATTCACAGGAAAAAGCGGAGGCAGCCACGGAAGAGGAGCAAGGGGGGAATCAAAAAGAGCATGACGTTTAA
- Protein Sequence
- MEERANILRAMNICRFCLDDKGPLTNIHEKDGGRDAKQSVPLPLQIMACVAIEVFQNDGMPQLICNTCRSHTNQAYIFKTTCKKSDDALKLFLATGNIQILKGSDKDFQASLMGSQKRTMSDKDQPLKQESKKIKTENAVVMLNNTKPLDAGKLLESAEHFGDEENSEHIMELDEGENVHEEIIENMSDEPEDEDEDDDDDDEDEMKINPILKVPQVQTDVFPCQYCERSFPLKQLLELHIKNHTRERSYGCSQCGRRFFTKYDLGKHIQTHSDARPYTCVVCQKQFARESLLHRHEKTHVDVPKYLCSSCDRTFLSRADLDAHSEKHKKKRPFSCRICKKSFVFKQGLERHEVSHSEEKPHKCNYCEASFTSPIKLMRHITSHAGLRPYPCKLCGRTFLLSHHLTRHMRSHYAAKNAESQPIGQHKCDICSMSFRRKDSLINHSTIHSMVNLKCVICNTAFDNAKQVMNHITTHLSGLPYPCDKCDYSFDTQDQLEEHEIKHAEMEYEDQIEQEVHLEATQNASSADKEEGDDSGDDVAEFTITNPENPEIVRRPRRATKIKNYAQFLKEELGSDVEDDLIQEEEPSEITPDLNTPEEQAIKPIVRIEGTKVYARKNLMEKPRVIPNVNVSRPQTAQPEQINQRLTTLENLGLTKQAVKALPNKQFVDMKIGDKTVRVQKLMMTKAEIDAMAKEGKIEMKGDTILLKKVPDKAMPFRHTMESIIDDVKPMVNPKPVVKKTYMKKINMDNSQEKAEAATEEEQGGNQKEHDV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00466735;
- 90% Identity
- iTF_00466735;
- 80% Identity
- -