Dhop036726.1
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- -
- Assembly
- GCA_033060865.1
- Location
- CM065425.1:76688941-76691266[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.75 83 5.4 2.4 3 23 48 68 44 68 0.91 2 11 0.00025 0.027 16.4 1.3 2 23 96 118 96 118 0.96 3 11 2.9e-06 0.00032 22.4 2.0 2 23 124 145 123 145 0.97 4 11 7.8e-05 0.0086 18.0 1.3 1 23 151 173 151 173 0.98 5 11 0.0014 0.16 14.0 4.8 1 23 179 202 179 202 0.97 6 11 6.2e-05 0.0069 18.3 2.2 1 23 207 229 207 229 0.97 7 11 4.9e-05 0.0054 18.6 0.6 1 23 238 260 238 260 0.97 8 11 6e-05 0.0067 18.3 0.3 1 23 265 287 265 287 0.98 9 11 3.8e-06 0.00042 22.1 0.8 3 23 295 315 293 315 0.97 10 11 4.3e-05 0.0048 18.8 1.9 3 23 323 344 321 344 0.95 11 11 8.7e-06 0.00097 21.0 3.2 1 23 350 372 350 372 0.98
Sequence Information
- Coding Sequence
- ATGGCGCGGGACGTCCTTGCGCACAAGGGTGAATTAGTCCTCGGATTTGCCTTGGCATTGACTAAAGCAAAAGCAGAAAATAAATTGGTGCACAAAGATGAAGGTTTTATTACCCCGAGGGAAACGCAGGAGTGCCCCATATGCAGGACGTGCGGTGGGATCTTCACCACCGTAAACCAGCTGAAGTGCCACATGACTCTCCATAGGTTCGATTCGCCCGTCAAATTTATGCTGTCGGAAGACAAACCGAGTTTTCTGCTAAACGAAAACGAGAAGAAAGGCCCCAAGTGTAGGACCTGCGGAAACACGTTCGTCAATTCCAGCCAACTGAAGTACCACAACATGACCGCGCACAAAGATAAGGTGTGTAAGTGCGATTTGTGCCCCATGTCGTTCTACACGCCGTACCTATTGAAAGTGCACATGCGCCGCCACGACACAAACAGGAAGTACAGTTGCGACATGTGCAAGGTCTCGTTTAAGCAGAAGTTCAATTTGGATCTTCACTTGTTGTCCCACGAGGGCAAGTACCCGTTCGCGTGTCAAATCTGCGACAAGGGGTTCATGAGGAAGGCGGTGTTGGAACACCATCACAACACCTGCCACCTGAACATCAAGTACAAGTGCGAGTTTTGCGAGAAGGAGTTCCGAAGCTCCGCCTACCTGAAGAGTCACTCGAAGCTGCACGATCCCAATCACATCCCCGAGTTGTACACGTGCGAGCTCTGCGGTTTGGACTATAAAAATCGTAAGGGTCTTCAACGGCACAGGAACGCGCACAGTGGAAAGGTCTACATCTGCGACGTGTGCGGGAAACAATTTCTTTCCACCGACAAGTTGAACGAGCACATGAGGAtccacaccggcgagaagccttaCGGGTGCGACACGTGCGGGAAAAGGTTCACCAAGAAGGACTTGCTCATTACGCATACGAGGGTGCACACGAAAGAAAAGCCGTACGGCTGCAAGGTGTGTGGGAAGTGCTTCACGCAACGCTCTTCGGTGAGAATCCACGAGAAAAACGTGCATTATGGGGATCGACCTTACCCGTGCTGCGTTTGCGGTAAGAAGTACAGCACCAAGAGTCTCCTCAACATGCACACCAAGTCACATGGGAATATTTCGAGTGAGATTACAAGTGAAATTAATTACTAA
- Protein Sequence
- MARDVLAHKGELVLGFALALTKAKAENKLVHKDEGFITPRETQECPICRTCGGIFTTVNQLKCHMTLHRFDSPVKFMLSEDKPSFLLNENEKKGPKCRTCGNTFVNSSQLKYHNMTAHKDKVCKCDLCPMSFYTPYLLKVHMRRHDTNRKYSCDMCKVSFKQKFNLDLHLLSHEGKYPFACQICDKGFMRKAVLEHHHNTCHLNIKYKCEFCEKEFRSSAYLKSHSKLHDPNHIPELYTCELCGLDYKNRKGLQRHRNAHSGKVYICDVCGKQFLSTDKLNEHMRIHTGEKPYGCDTCGKRFTKKDLLITHTRVHTKEKPYGCKVCGKCFTQRSSVRIHEKNVHYGDRPYPCCVCGKKYSTKSLLNMHTKSHGNISSEITSEINY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00466681;
- 90% Identity
- iTF_00466681;
- 80% Identity
- -