Dhop009437.1
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- -
- Assembly
- GCA_033060865.1
- Location
- CM065420.1:19498428-19505437[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.12 14 7.9 0.5 1 23 350 371 350 371 0.93 2 12 0.012 1.3 11.1 0.1 2 23 374 396 373 396 0.93 3 12 4.7e-07 5.2e-05 24.9 2.2 2 23 458 479 457 479 0.97 4 12 0.0005 0.055 15.4 0.4 1 23 485 507 485 507 0.97 5 12 3.9e-05 0.0043 18.9 1.3 1 23 513 535 513 535 0.98 6 12 3.3e-05 0.0037 19.1 1.5 1 23 541 563 541 563 0.98 7 12 0.00029 0.032 16.2 0.7 1 23 569 591 569 591 0.98 8 12 8.8e-08 9.8e-06 27.2 1.8 1 23 599 621 599 621 0.98 9 12 0.0038 0.42 12.6 0.2 1 23 627 649 627 649 0.96 10 12 2.7e-05 0.003 19.4 1.3 1 23 655 677 655 677 0.98 11 12 0.00032 0.036 16.0 0.6 1 23 683 705 683 705 0.98 12 12 6.7e-05 0.0074 18.2 2.1 1 23 711 733 711 733 0.98
Sequence Information
- Coding Sequence
- ATGGCGGTCGCGGACACGACGAGATATGGAGAGTTGTGCAGGCTGTGCGCATCAAAAACGAGCTTGGTTTTAGGCATTAATATATTCGAAAGCGAGGGCAGCATACgtgaaataaacaagaaaatcgAAGCTTGCCTTTCAATTCGGgtACATGAAACTGATGAACTACCAAAAATGGTGTGCGGTCACTGTGTCTACAAACTGGAAAAATTTTTCGATTTCAGACAGCATTCACTACACACAGAAAACTTACTCATAGACATGTATAAAGAATTAAATGCGACGAGACTCCAAAACGAGCAGATGAAAATGAATGTTGTCATAGACCACCCTGACCTAATCATGGTGCAACAGCACCACTTATTGAACGACACCATCCACGGCGTTACGGAATTGGATTTGAATCAGCTAAGCCACAGAGAAAATATGATAGTGGAACAGGTTGAGCACCAAATCATTTTGAGCCATCAAGATGTCGACATTAATGCCCACTCGTTGGATAATATTAGCTTACATCACCATGAATTGACTAATCAACATTTGTCCAATCACAGTTTACAAACGCAAGATACTATTTTAGTCGATGAATCTAGCAGTGTGCATACAACTTATTCGGAAGCTAACTTGGAGCTTATTCAACAGGACCATCAACTTGGAAATTATGCCTCGGAATATAGTTTGAGCGATTTAAATTTACATGAGGAAACAAATATTCAAACACATGATAAGGATAAACATCACACAATAATTCAAGAGAATCATGCTCTCGAGCCCCACATCCCACCAGTGCAGCAAATGAAATCACCCAGCAACAAAATCGATGGAAATCAAGAGACAGATATCAAATacgaaatagaaataaaaaatgacattttaaaaaatgaatacaAGGCTGACAACTTACATGAGTTGGTTAAACATGAAGACAGCAACAGTGAGAACCGTTTGCTGATTGACGAGAATGACAAAACCGATATGTTTGTGCTCAACGAAGTCGGAGATGATATTACTTACTCGAACGTTAGTTCAAGTGGTGATAAAGGAgtgtttttttgtaatttatgcgGTAAGGCCATCAACAAGGCGGATTTCCAAGTGCATTATGACCAGCATTTTAATAAATGCATGGTGTGTTTAGCAGTTTTTTCAAATAAGGATGCGCTTAATGCACATTCGAAAGAAGCTCACGGAGCAAGCCCTGAAAAAATTAGGCAAAATATAAGAGAAAGACTGAAAAGAGCCAGTGCTGATAATAATGACAGTAATAGTGATAGTGACGATTTAAATAATTCTGGACCGTTAAAAAATGAGGAGGACGAAGATGATCCGGTTACAGAACCGACGAGTAAAACTAAAAAGTGGTCACCTAAAGTTTGTAAAGAATGTGGGAAATCGTATAAAACTAATTATAAACTAACTGAGCATATGAGAAAGCATACAGGAGAGAAACCATATAAGTGTAGTTCTTGCGAGAAGGCCTTTCGTTCTAAGATAGGACTAGCACAACATGAAGCAAAGCACACTGGTCAGTATGACTATTCTTGTCCAATTTGTGGAAAAGGTTTCCAATGCAAAAGTTACCTTATGGTACACCAACGTGTACATTCAGATGTCAAACCCTATCCATGTACAACGTGCGGCCAAAATTTCAAGTCAAAACAGTCATTAATGGACCATACAAATAGGCACTTAGGAGTTAAACCGTACATGTGTGATATATGTGGAAGAGGTTTTATTACCAAAGGTCTGTGCAGAGCACACCAAAAAGTACACACAGGTTTAGATAATAGAAAATATTCATGTAAAGTCTGCAATAAAATGTTCGTGTCCAAGAGTTACCTGCAAACTCACATGAGAATACACACAGGAGAAAAGCCTTTTATGTGTGAGGTATGTGGTAAAGGATTTTTGACGAGAGTAGATCTTCGCATCCATTCCACGATGCACACGGGTGAGAAGTCTTACGTTTGTGAAATGTGTGGTAAAGCATTTGCACGAAGGGATGCTTTGAGGTGTCATCGAAGATCCCATACGGGAGAAAGGCCTTACACTTGTGATCAATGTGGGCAAACATTTACACAATTTTCCCCGATGGCAATACATAAACGCCTTCACACTGGAGAGAGACCGTATTCATGTGAAGTTTGTGACAAAAAGTTTGTTTCCAAGTCTACAATGATGACACATTCTAAAAAGCATGACTTCTCAAAATACCATAACGTTTCTCAGAATGGTACATcttaa
- Protein Sequence
- MAVADTTRYGELCRLCASKTSLVLGINIFESEGSIREINKKIEACLSIRVHETDELPKMVCGHCVYKLEKFFDFRQHSLHTENLLIDMYKELNATRLQNEQMKMNVVIDHPDLIMVQQHHLLNDTIHGVTELDLNQLSHRENMIVEQVEHQIILSHQDVDINAHSLDNISLHHHELTNQHLSNHSLQTQDTILVDESSSVHTTYSEANLELIQQDHQLGNYASEYSLSDLNLHEETNIQTHDKDKHHTIIQENHALEPHIPPVQQMKSPSNKIDGNQETDIKYEIEIKNDILKNEYKADNLHELVKHEDSNSENRLLIDENDKTDMFVLNEVGDDITYSNVSSSGDKGVFFCNLCGKAINKADFQVHYDQHFNKCMVCLAVFSNKDALNAHSKEAHGASPEKIRQNIRERLKRASADNNDSNSDSDDLNNSGPLKNEEDEDDPVTEPTSKTKKWSPKVCKECGKSYKTNYKLTEHMRKHTGEKPYKCSSCEKAFRSKIGLAQHEAKHTGQYDYSCPICGKGFQCKSYLMVHQRVHSDVKPYPCTTCGQNFKSKQSLMDHTNRHLGVKPYMCDICGRGFITKGLCRAHQKVHTGLDNRKYSCKVCNKMFVSKSYLQTHMRIHTGEKPFMCEVCGKGFLTRVDLRIHSTMHTGEKSYVCEMCGKAFARRDALRCHRRSHTGERPYTCDQCGQTFTQFSPMAIHKRLHTGERPYSCEVCDKKFVSKSTMMTHSKKHDFSKYHNVSQNGTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00466668; iTF_01258375;
- 90% Identity
- iTF_00466668; iTF_01258375;
- 80% Identity
- -