Dhop019599.2
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- -
- Assembly
- GCA_033060865.1
- Location
- CM065422.1:28869370-28871814[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 5.2e-05 0.0057 18.5 1.5 1 23 144 166 144 166 0.98 2 11 0.0002 0.022 16.7 6.8 1 23 178 200 178 200 0.99 3 11 0.00019 0.022 16.7 1.3 3 23 208 228 206 228 0.96 4 11 0.0014 0.15 14.1 0.0 2 23 235 256 234 256 0.97 5 11 1.1e-06 0.00012 23.7 1.4 1 23 262 284 262 284 0.96 6 11 0.00041 0.045 15.7 2.3 1 23 290 312 290 312 0.98 7 11 2.5e-07 2.8e-05 25.8 4.4 2 23 319 340 319 340 0.98 8 11 8e-06 0.00089 21.1 0.4 1 23 346 368 346 368 0.98 9 11 3e-07 3.3e-05 25.6 2.1 1 23 374 396 374 396 0.97 10 11 6.7e-06 0.00074 21.3 2.6 1 23 402 424 402 424 0.98 11 11 0.0045 0.5 12.4 1.8 1 23 430 453 430 453 0.93
Sequence Information
- Coding Sequence
- atgaaagaatttatGTCAGCAGAAGCGTGTAACATTTGTCGCAGCTGTTTAACTCTTTGCAATAAAGACAATTACATTAATATCTTTGATCAAGACAAGAAATTCGCTTTAATGTTGATTCAATGCGTTTCTGTTGGGATATCCGAAAATGACGGTTTGACTAAGCTTTTGTGTGAAAAATGTGccgaaacattaaatacagctTACAAGTTCAAGAAACAATGTGAGAAGTCAGATGTATATCTACGCAACCaattaaaacgatttaattGCAAGAACCAAGGTGATGAGAGTCCCCCTAATGAATCAGAGGAAAAAAGCAGCGATAATGTTTATTATGATAATGAGGTACCATATTTAGATAATGATTGGTCCTTGTGTGAGACTGAtgctaacaaactgaaagaaaaaTCAATTATCAAAGATAGATTTTCCTGCAAGTTATGTAAAAAGAGTTTTGCAagaataaattctttaaatgttCACTTGACACGTCATGAAGATAAAGGCAAATCTTCTGTCATTCGTCCATATAAGTGTATGCaatgttcgaaatgtttttTCACCACAGATAGTTTGAGTAAACATATGAAGAGACATACTGGAGAGAAGCCACACCTGTGTTCCACTTGTGGAAAAGGATTTGGAGCTGCAAGCACTTTACATATTCATATGCGAATTCATTCTGGAGAAAAGCCTTTACAATGCCCATCATGTCCAATGCGTTTTGCTGCTCAAGCTGGCTTGAGTGTGCACTTAAGAAAACACACTGGAGAGAGACCTTACTTATGTTCAAACTGTGGTCAAAGTTTTAAGTCTAGTTCTGATTTAACAATTCACTTTCGCACACACACCGGAGAGAAACCATATTCATGTGATTTATGTGACAAAAAATTCCGAACGTCCTACATGAGATTAATGCACAGACGATGGCATACTGGAGAAAAGCcagcaaaatgtaaaatttgtcagAAAAGTTTTACATCGAATGGTCATTTAAACATGCATATGCGTACACATGCGACAGTTAAACCTTACAATTGCACAACATGTGACAAAGCCTTTATAACATCTAAAGACCTAGAATTGCATACAATGGTACATACTGGAATGAGGCCTCACATTTGCCCAAAATGCAATAAAGGCTTTAACAGATCCAACAATCTGGCGAAACACATGCGTTTGCACCTCGGCTTAAAACCACATACCTGTGAGGTGTGTAAGAACTCGTTCAGCACTAGCAGTCAGTTAAAAATTCATGTTCGGAGTCATACAGGTGAAAGACCTTACTCTTGCATTTTATGTAAGAAAGGATTTGTGAGTTCAGGTAGTCTGGCAAGGCATAAACGTCATCAACATATAAGTGAAAAAGCTCCTGTAATTTGA
- Protein Sequence
- MKEFMSAEACNICRSCLTLCNKDNYINIFDQDKKFALMLIQCVSVGISENDGLTKLLCEKCAETLNTAYKFKKQCEKSDVYLRNQLKRFNCKNQGDESPPNESEEKSSDNVYYDNEVPYLDNDWSLCETDANKLKEKSIIKDRFSCKLCKKSFARINSLNVHLTRHEDKGKSSVIRPYKCMQCSKCFFTTDSLSKHMKRHTGEKPHLCSTCGKGFGAASTLHIHMRIHSGEKPLQCPSCPMRFAAQAGLSVHLRKHTGERPYLCSNCGQSFKSSSDLTIHFRTHTGEKPYSCDLCDKKFRTSYMRLMHRRWHTGEKPAKCKICQKSFTSNGHLNMHMRTHATVKPYNCTTCDKAFITSKDLELHTMVHTGMRPHICPKCNKGFNRSNNLAKHMRLHLGLKPHTCEVCKNSFSTSSQLKIHVRSHTGERPYSCILCKKGFVSSGSLARHKRHQHISEKAPVI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00466680;
- 90% Identity
- iTF_00466680;
- 80% Identity
- -