Basic Information

Insect
Dorcus hopei
Gene Symbol
-
Assembly
GCA_033060865.1
Location
CM065419.1:40518860-40521244[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.1 1.2e+02 4.9 0.3 2 20 160 178 159 180 0.94
2 16 0.078 8.7 8.5 6.0 1 23 184 206 184 206 0.98
3 16 0.18 20 7.4 0.2 2 20 325 343 324 345 0.94
4 16 0.024 2.7 10.1 2.7 1 23 349 371 349 371 0.96
5 16 0.0031 0.35 12.9 2.2 2 22 421 441 420 441 0.95
6 16 0.0053 0.58 12.2 2.7 1 23 445 467 445 467 0.96
7 16 0.004 0.44 12.6 0.9 1 23 475 497 475 497 0.94
8 16 1.2e-06 0.00013 23.7 3.4 1 23 503 525 503 525 0.98
9 16 8.6e-06 0.00096 21.0 0.3 1 23 534 556 534 556 0.98
10 16 6.9e-05 0.0077 18.1 1.8 1 23 562 584 562 584 0.97
11 16 0.0028 0.31 13.1 2.0 1 23 590 612 590 612 0.97
12 16 4.6e-07 5.1e-05 25.0 1.7 1 23 618 641 618 641 0.97
13 16 0.00036 0.04 15.9 0.4 1 23 647 669 647 669 0.94
14 16 0.00017 0.018 16.9 5.4 2 23 676 697 675 697 0.96
15 16 4.9e-06 0.00054 21.7 2.3 1 23 703 725 703 725 0.97
16 16 1.1e-05 0.0013 20.6 4.7 1 23 731 753 731 753 0.98

Sequence Information

Coding Sequence
ATGGCCAAAGTATGTAGGCTCTGCTTACAAATTACAGGAGATTTGTGCTTTACCATCGATGAAAACGCTGTGGTAAAAAGCCGAAATAAAATCATGGTTTTAATGCCAGAACTTGAACTTAACATTGTAGCCGAACCCGTTCTTTGTGAGTTGTGCTATGGTACACTACATGCCGCTTATGAATTCAAGTGCATCTGTCTGGCTAATGAACAAAGAATTATCGAGTATTTGAAGAATGGAAAACACCCTCCAATAAACTTGTGCGATTTATTAGAAGTTGACTCAAAAAATGCAATTGCAATGACGTTACTGGAGGAAAATTTTAAAGGGAATGTGAGCGCAGACATCGTAAAGAAGGAGCCATTCGAGTTTGAGAATGTATACGAAGACTCGTACAAGGAAATGAATGTGATTgttaatgatgaaaataatgAGACAGATAAAAGTGATGAGACTTCAGTTAAATGTGGTGGCATTAAGTGTTCAAATTGTTCCAGCGAGTTTGTAGTTTTGAAGGAATATAGAAAACATCTGACACAATGTGCGCGCTATGAGTGTGACAAGTGCAGCAAAAAATTTATGCTGAAGCATAGATTTCTAAAACATCAGAAATTGCATCGTAAGAAAAATGCACAGGAAGGTTCAACAAATGTGAGTTTTAAGCCAGAACGAGATGAAAGCGATCATTCGGCAATTAAAGGATATATGAGTCCTAATCCAGAGCAAGATGAAAGTAATGAGTCAGAAATTAAAGAGTGTGCAAGTCCTAAGCCAGAGCAAAATAATGAATCAGAAATTAAAGGATGTGTAAGCCCTAAGTCAGAACAAGATAGAAGCAATCAATCAGGAATTGAAGAGTGTGTGAGTTCTGAGCCAGAACAAGATAAAAGCAGTCGATCAATAAATGAAGATTGTACAAGTTCTGAGCTAGAACAAGATAAAAACAATCCGGCAATAATTAAAGGGGGTGTTAAGTGTTCAAACTGCTCGGCTGAGTTTACGATTTCGAAGGAATATAGGAAACACTTAGAAGAATGCTCCCCCTACAAATGTGATatatgcaataaaaaatttatgttgGAGAGGCGATTTCTACGACACAAATTATCACATAGGACAGACAGAGGCAAAAGTAAAAGTGATGACTCGCAAATTAACCATAGTGTAGATAGCAATGAGCAGTTGGATAAAGTAATCGATGTGAATCTTGATATAGAACCAGAAAAAAGGAGTGaaactgaaattaaactgaACTGGATTAAGTGTTCAAACTGCCGTAATAAATTTACGTCTAACAAAGACTATAGAAGACACATAAGAAAATGTGCTCCCCATAAATGCGATGTTTGCAATAGAAAATTTATGTTGGAAAGCAAATTAGAGCGACACAAACTATTGCACAGCGCAGATTCAGAACAAACATTCCTGTGCGAAGTGTGCAGCAAAATGTTTCGAAGCGGTTATCGCTTGAGACAACATCTTTTGTTGCACACAGGGTTGAAACCCTTCAAGTGCCCGATGTGTGATAAAATGTTTCCAACGAAACATAACTTGAATTCGCATAAACAGAGTCACTTGAATAAGCAAAAGGAATGGCGGCATGTATGCGAAATATGTGGGAAAAAATTTGCCGCTCCTGTTGGTTTGCGAAGGCACAGAAACACACACATAAAAGAGAAGAagttcttttgtaaaatttgtgaTAAGGGCTTCAATATCAGCTTTTACTTACAGGAGCACATGAAGAGGCATATAGGTGAAAAACCACACGTATGCGATATTTGTAATTCACGGTTCATCACAAAGCAAAGATTAATAGAGCACTATCGCAGCCACACCGGTGAGAGACCATATAAGTGTAAGAAATGTGAGAAGAGCTTTGCACAAAGCAGTACTTTAAGAGAACACATGATGTACATACACTCGGATGAAAAACCTTTCAATTGTGACgtgtGTGAAAAAAGGTTCCCTATGAAGGGCGACCTTCAAAAACATTCACTTTTACACATGGAAAAGCCTAATCTTCCTTGTTCCTACTGCGACAAAACTTTCCACTCAAATCATACCTTAAGGCAGCACGTTAAGAGACATACAGAGGACCCGATGCACATGTGTAGTGTGTGTAGTAAAGCTTTCTTTAGATCTAGTGAATTGAAGAAACATATGCTGATTCACACTGGGGAAAAACCTTTCGAGTGTGATGTCTGCCATCAAAGATTCAATCAAAAATACAACTTGCACGTGCACATGAAAGTACATTTGAAGAGTTCATGA
Protein Sequence
MAKVCRLCLQITGDLCFTIDENAVVKSRNKIMVLMPELELNIVAEPVLCELCYGTLHAAYEFKCICLANEQRIIEYLKNGKHPPINLCDLLEVDSKNAIAMTLLEENFKGNVSADIVKKEPFEFENVYEDSYKEMNVIVNDENNETDKSDETSVKCGGIKCSNCSSEFVVLKEYRKHLTQCARYECDKCSKKFMLKHRFLKHQKLHRKKNAQEGSTNVSFKPERDESDHSAIKGYMSPNPEQDESNESEIKECASPKPEQNNESEIKGCVSPKSEQDRSNQSGIEECVSSEPEQDKSSRSINEDCTSSELEQDKNNPAIIKGGVKCSNCSAEFTISKEYRKHLEECSPYKCDICNKKFMLERRFLRHKLSHRTDRGKSKSDDSQINHSVDSNEQLDKVIDVNLDIEPEKRSETEIKLNWIKCSNCRNKFTSNKDYRRHIRKCAPHKCDVCNRKFMLESKLERHKLLHSADSEQTFLCEVCSKMFRSGYRLRQHLLLHTGLKPFKCPMCDKMFPTKHNLNSHKQSHLNKQKEWRHVCEICGKKFAAPVGLRRHRNTHIKEKKFFCKICDKGFNISFYLQEHMKRHIGEKPHVCDICNSRFITKQRLIEHYRSHTGERPYKCKKCEKSFAQSSTLREHMMYIHSDEKPFNCDVCEKRFPMKGDLQKHSLLHMEKPNLPCSYCDKTFHSNHTLRQHVKRHTEDPMHMCSVCSKAFFRSSELKKHMLIHTGEKPFECDVCHQRFNQKYNLHVHMKVHLKSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01258369;
90% Identity
iTF_00466655;
80% Identity
-