Dhop004427.1
Basic Information
- Insect
- Dorcus hopei
- Gene Symbol
- -
- Assembly
- GCA_033060865.1
- Location
- CM065419.1:18150733-18159804[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 3.1 3.5e+02 3.5 0.1 2 17 52 67 51 68 0.90 2 13 0.032 3.5 9.8 0.0 2 23 149 170 148 170 0.95 3 13 0.0013 0.14 14.2 1.2 2 23 177 198 177 198 0.97 4 13 1.1 1.2e+02 4.9 0.6 12 23 201 212 200 212 0.88 5 13 1.6e-05 0.0018 20.1 0.2 3 23 220 240 218 240 0.96 6 13 1.1e-05 0.0013 20.6 0.3 2 23 247 268 246 268 0.97 7 13 1.5e-05 0.0017 20.2 5.6 1 23 274 296 274 296 0.97 8 13 7.2e-06 0.0008 21.2 2.1 1 23 302 324 302 324 0.96 9 13 3.6e-07 4e-05 25.3 0.4 1 23 330 352 330 352 0.98 10 13 5.7e-06 0.00063 21.5 0.3 1 23 358 380 358 380 0.98 11 13 1.3e-06 0.00014 23.6 1.0 1 23 386 408 386 408 0.97 12 13 2e-06 0.00022 23.0 0.8 1 23 414 436 414 436 0.97 13 13 0.11 12 8.1 0.0 1 17 442 458 442 459 0.89
Sequence Information
- Coding Sequence
- atggaAGAAGTCTGCATAAGAAATAGTGATACGGTTTGCAGGGCATGTCTActggaaaaagaaattatgcaTTCTTTGTTAGAAGAAAACGTGAAACACATGTTCGTTTCGTGCACATCCCTAcaaGTGGACGAAGCCAAGCTATCTTTCTTGATTTGCGAAGAGTGCAAAGCCAGCTTAAATAATGCTTACAATTTCAAGCAGCAGTGTTTAAGATCACAGAACATTCTAGAACGTTACCACAGCTCAAGTAAAATAGAGCCCATCAGGTCAAATGAATCTAGCCTATTGGAATATTTAAAAACTGATGAATTCCTAGGAAATTCAACTGAGAATGATCTGTTTAATCTAGATGACAGTGAAAGTGTATTTGAATCATTGGATGTTGATCAGAAGATAGTAAAAccaaaaagaaacaagaaacttGTGAAAGACTTTCCCATTAAATGTCCATTTTGTTTTGAGGGGTTTGACTTACAATCTGACCTAGACATACACTTGATTGCACATCCAAAGGATGAAGAGCCTACATGCACTTTGTGCAACAaagaatttatgaatttaaaggtTTTAAGGCGGCATGTAAAGATTCATATGAAGAAATCGGGTAGTTTAACAAGGCATTTACGGAAGCATAGTGGTGAAAAGAGACACCTGTGTCCTGTGTGTGGCAAAAGTTTTTATGAGGCTAATGTCCTCGCAGTTCACATGAGAACACATACTGGGGAGAAGCCAATAGAATGTAATATATGTTCTAGAAGATTTTCTGATCCAAATGGTCTGCGTAGTCATTTGAAGTCACACACTGGGGAAAAGAATCATTCGTGCAATATTTGTAATAAATCCTTTTCACATTCTTTCGTGCTTAAGAAGCATTTAAGAGTGCACAGTGGTGAGAGACCCTATTTATGTTCAGTTTGCGGGAAAAGCTTCACTCAGAGCCATTATGTGTCGGTTCACATGCGTCAGCATACTGGTGAACTGCCTTTCGTTTGCAAGATCTGCAATAAAGGTTTCGCACAAAACAGTCAAATGGAAATGCATATGCGTGTACACACCAGAGTCAAACCATACATTTGTGCTGTTTGTGGTAAAGGCTGTGCAAGATCTGGTGATCTGTCTACTCACATGAGATCTCATACTGGTGAAAAGCCATTTGCTTGTGCACTTTGTCCAAAAAGATATGTAACTTCGAGTCACCTGACGGTTCACATGCGTAGTCACAGAGGGGAAAGGACCCACATGTGCACGACATGTGGAAAGACATTTGTAGAAGCGCAAGGTCTTAAGGCTCACATTCGAACTCATACTGGTGAGAAGCCGTACATGTGTGCTGTGTGTGGACATCGATTTGCACAGTCAGGTCAGTGGAAAGTTACATTTCACTTCCTGAAGATGCTCGGAATAAGAGAACTAAACTTCCAAGTGTTAAAAGATCAAGTGAAGGGGACGCTTACGAAAAAAGAAATCCATGCTTACGAAGAAAAAGACAACGACAACAACGTCAACCGAAAGAACAAAGCATTTCTACCATCCCCTTCGTGTTGA
- Protein Sequence
- MEEVCIRNSDTVCRACLLEKEIMHSLLEENVKHMFVSCTSLQVDEAKLSFLICEECKASLNNAYNFKQQCLRSQNILERYHSSSKIEPIRSNESSLLEYLKTDEFLGNSTENDLFNLDDSESVFESLDVDQKIVKPKRNKKLVKDFPIKCPFCFEGFDLQSDLDIHLIAHPKDEEPTCTLCNKEFMNLKVLRRHVKIHMKKSGSLTRHLRKHSGEKRHLCPVCGKSFYEANVLAVHMRTHTGEKPIECNICSRRFSDPNGLRSHLKSHTGEKNHSCNICNKSFSHSFVLKKHLRVHSGERPYLCSVCGKSFTQSHYVSVHMRQHTGELPFVCKICNKGFAQNSQMEMHMRVHTRVKPYICAVCGKGCARSGDLSTHMRSHTGEKPFACALCPKRYVTSSHLTVHMRSHRGERTHMCTTCGKTFVEAQGLKAHIRTHTGEKPYMCAVCGHRFAQSGQWKVTFHFLKMLGIRELNFQVLKDQVKGTLTKKEIHAYEEKDNDNNVNRKNKAFLPSPSC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00466615;
- 90% Identity
- iTF_00466615;
- 80% Identity
- -