Basic Information

Insect: Dorcus hopei
Gene Symbol: Zfp42
Assembly: GCA_033060865.1
Location: CM065425.1:76622458-76629238[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.00013 0.015 17.2 0.7 2 23 108 130 107 130 0.94

2 21 0.021 2.3 10.3 0.6 2 23 184 205 183 205 0.96

3 21 0.29 32 6.7 0.2 1 23 225 247 225 247 0.97

4 21 0.57 64 5.8 1.3 1 20 251 270 251 271 0.95

5 21 0.47 52 6.1 0.9 1 23 279 302 279 302 0.94

6 21 0.31 34 6.6 0.2 1 23 308 330 308 330 0.96

7 21 0.011 1.2 11.2 0.9 1 23 338 361 338 361 0.96

8 21 0.0014 0.16 14.0 0.6 2 23 373 394 372 394 0.98

9 21 6.5e-06 0.00072 21.3 1.2 3 23 406 426 404 426 0.96

10 21 7.2e-05 0.008 18.1 0.9 1 23 432 454 432 454 0.98

11 21 6.3e-05 0.007 18.3 0.3 1 23 460 482 460 482 0.98

12 21 0.00062 0.069 15.1 0.8 1 23 1187 1209 1187 1209 0.96

13 21 0.003 0.33 13.0 3.8 1 23 1214 1236 1214 1236 0.97

14 21 0.00096 0.11 14.5 2.1 1 20 1242 1261 1242 1263 0.93

15 21 1.2e-05 0.0013 20.5 1.0 1 23 1271 1294 1271 1294 0.97

16 21 0.003 0.33 13.0 3.1 1 23 1299 1321 1299 1321 0.98

17 21 0.00062 0.069 15.1 1.3 2 23 1331 1353 1330 1353 0.95

18 21 3.9e-05 0.0043 18.9 0.6 1 23 1358 1380 1358 1380 0.98

19 21 2.8e-06 0.00031 22.5 0.0 1 23 1386 1408 1386 1408 0.98

20 21 0.00038 0.042 15.8 0.1 1 23 1414 1437 1414 1437 0.96

21 21 3.8e-05 0.0043 18.9 1.4 1 23 1443 1465 1443 1465 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.00013	0.015	17.2	0.7	2	23	108	130	107	130	0.94
2	21	0.021	2.3	10.3	0.6	2	23	184	205	183	205	0.96
3	21	0.29	32	6.7	0.2	1	23	225	247	225	247	0.97
4	21	0.57	64	5.8	1.3	1	20	251	270	251	271	0.95
5	21	0.47	52	6.1	0.9	1	23	279	302	279	302	0.94
6	21	0.31	34	6.6	0.2	1	23	308	330	308	330	0.96
7	21	0.011	1.2	11.2	0.9	1	23	338	361	338	361	0.96
8	21	0.0014	0.16	14.0	0.6	2	23	373	394	372	394	0.98
9	21	6.5e-06	0.00072	21.3	1.2	3	23	406	426	404	426	0.96
10	21	7.2e-05	0.008	18.1	0.9	1	23	432	454	432	454	0.98
11	21	6.3e-05	0.007	18.3	0.3	1	23	460	482	460	482	0.98
12	21	0.00062	0.069	15.1	0.8	1	23	1187	1209	1187	1209	0.96
13	21	0.003	0.33	13.0	3.8	1	23	1214	1236	1214	1236	0.97
14	21	0.00096	0.11	14.5	2.1	1	20	1242	1261	1242	1263	0.93
15	21	1.2e-05	0.0013	20.5	1.0	1	23	1271	1294	1271	1294	0.97
16	21	0.003	0.33	13.0	3.1	1	23	1299	1321	1299	1321	0.98
17	21	0.00062	0.069	15.1	1.3	2	23	1331	1353	1330	1353	0.95
18	21	3.9e-05	0.0043	18.9	0.6	1	23	1358	1380	1358	1380	0.98
19	21	2.8e-06	0.00031	22.5	0.0	1	23	1386	1408	1386	1408	0.98
20	21	0.00038	0.042	15.8	0.1	1	23	1414	1437	1414	1437	0.96
21	21	3.8e-05	0.0043	18.9	1.4	1	23	1443	1465	1443	1465	0.98

Sequence Information

Coding Sequence: ATGATCTCTCGGATTCTAGAAATTACGGGGTTTATATACAGTTTGGAACTCGAACAATTCCGAGTGTTAACGAAGGGAGTATGTACATTGTACATAAAAATACCTGTGATCATAAGAACTTTTAAGCCAGAGGTGAACAGCAAGGGGAAACGTATTTTCTCCAAACCGGTCACCCCCGACATCATACGACTTCCCCTAATCGAAGACTTCGTGAAGACGAGGACCAAGCTCGTCGGCGAAAGCGCTCGGAACGAGATCAAAAAACTGTTGGTCTACAGGGAGCactcttattcgaaatttaaatgTAGGGTGGGGCGGGTGACGTGCAGCGAGTGCGGCACCGTGTTTCGGACTGCCTATGGCCTGAAGATGCACAAGCGCTTTAAGCACAGGGCGAAGCCGTACGCCTGCAAACAGTGCGAGTTATTTCTGTCTACGTTCCTGAAAACGGAAAACCTTGAAGACTGGAGCAGATATAACATTTTCCTAAAGAGGAAGCGTCGTCGGGACTCGAAGATGGCCAGGAAGAAAATGAGGAAGGGCAAGTGGGAGTGCAAAAAGTGTAACGCGGTTTTCGACCTCGTCAAACAGCTGCGACAACACAGAAAGGAGCACAGGCTTAAACCCGATGAAGTCAAATACAATTACACTTACAATAAAACAGAGGACACGTACAGCTGCAATACATGCGATAGTGAGGCTAACACGCGAGAGGAAATGGAGAAGCACGTACAGTTACACGAAGACACTTACATCTGTCAGTCGTGCAAGTCGTCCTTCGAGACTGCTTACAACTACGCTTTACATCTTTGCCCCAAAAGCGAAGATGGGGCGTTCAAGTGTCCACTGTGCGATTTTAAAACCCTCAGGAGGCCCACCATTAGGAAGCACATCAATTCCATGCACTTCAACAAGTTCATTTATTACTGTAGCTTCTGTGGAAAGGGCATCGATGACGTCCTCAACTTCCGAGAGCACGAAGCCACTCACCTGCAGAGCGGAAAAAAGCAGTTTTCCTGCGTGGTCTGCGCCAAGGAATTTTCGTTCTCGCGGTACTTGCTGACGCACCAAATTCGAACGCACAAGGCCAACATAGAGGGCATAATTCTGCCAAATCAGTGCCCGATTTGCAAAAAGAATTTCGCCAAGCGCGTCAGCGTCGACAACCACATGCTCAAGCACGACCTAACCTTACCGCTCGAAAAGAAGCACCTGTGTGATATTTGCGGGAAAGGGTTCGTCAGGAAAGACAAGCTGAAAATCCACTACAGGGTGCACACCGGCATCAAGCCCTACACCTGCAGCTACTGCGCCAAGAGCTTCATCAAAAAGGACTACCTGATCATGCACGAGCGTATTCACAGCGGCGAAAAACCGTACGCCTGCGAATATTGCGGAAAGTGCTTTAACCAGGGGGCCCCCTTGAGAATACACGTGCGAATACACACGGGCGAACGGCCaTCTCCCGAAACGAGACGGCGCGTTAGGTGGACCCCCGATTCACTCATTAAAGCCTTGAATCTGGTAAAAACTGGCAAATCCATAAGGGTTGCGGCGCGCATCTCGAACGTACCGTACTCGACCCTCCAGGGACGGCTGCAGCAAGGAAATTTCGTGGCACCGCGGCTCGGAAGGCGCACTGTTTTCAATCCGGAGCAAGAAGAAGATATAGCTGCGCAAATTAGGTACCTTTCGAATTTCTTCTACGGCTTCACCGGTATCGAAATAAGAAAGATGGCTTACGAGTACGCCAGGAAAAATAACATCAAGCACAACTTTAATGAAACCTTCGAAATAGCGGGGATTGACTGGCTAAGAGGATTCTTGCGTAGGAACAATTTGCCCGTTCGCAGATCAGAAGGTGTAGGTCTGAATAGAAGGGCGGCCCCGAAGGAAGAGGAGGTCAAGTCGTTTTTTGCTTTGCTGAAGGATTTGATGGATAAGCACAAGTTCCAAGCTAAAGGTATATACAACGCAAGTGAAATTGGGATTGCGCCCGACAAAATGCTGAGCGGGGAAAGGAGTAACCTAACGGCTATGTGCGCAATGAGTGCTGAGGGTACGTACGTTCCCCCCATGTTCATCTACCCTCGCAAGAGACATTCCACCACGCTGGAAAGAAATGGCCCTACGGGTGCTAAATACGCGTGTTCGAGGGACGGCCAGATCAACGAAAACCTTTTCCTCACTTGGCTCAAACATTTTGCCAAGAACGTCAAGCCATCCGAAGGTGATCCTGTTTTGTTAATCCTCAGAAACCGCGCCAGCAAATTTTCTTTGCGAGCTTACGACTTTTGCCAAGAGAATCACATTGTGATGTTGTCAATTCCCCCACGCGGCGTTCAGCCATTGGCCGTATCATTTTTCGCATCGTTAAGAGCCGCGTATATAGAGAGGTGCAATCTCTTTAGGCAATTACAAGCGGGACGGGAGATTACTCACGCTGACATTGCATCACTTTTTAAAGAGGCGTTTGAGAGCGTTGCTTCTCCCGACAAGGCAGAAATTGGTTTTCTGGCTACAGGAATCCATCCTGTAAATCCAAAGGTGTTGAATGAACCTGGCTTTCTGCCTGTGGACGTCTTGAAGAATAGTGCTTTTCTTGAATGTATGGAAGAATACAAGCTGGTTAATAGAAAATCCATGGTGAAATACTACAAGGTTCTACTTAAGTCCGTGAACCAAGTGACCAAGAAGGTGGTGGAACAAACGTACCTTATACCGGAGTCCTCTTTAAGCCCAGATATACGAAAGAGATTCCGGAGAACGGAAGAATCTAATCCGAAGGCACAAACTCAACCTTTTATTCCGAATGTGGCTCTGGGCCAACACTTAAAATCGACGTTGCTGGCGAGCCTGAAGGATAAAACCCTGACATCCCGTCAGTCGCAAAATCTAATAATAATGGGCGCCACGAGCAGGGATAACGCGCAGAACCAACAGAATGTTGTTGCGAGTCGGAACAACACCCAAAGTCTTTTAATTCGGAAGTTTCCTTCACTTCGACAGTTCCAAGGGGGTATCGTCGGTTCGGTTCGGAGCAATTCACAAGCTCAGAAATTACCTGCAAGCCCACATTTCCCAGAGGCACTGCGGAGAAcccaaaaagttaattttaatagtttGACGTGCTATCAAAACAAGATCCAGGGTGTTACCAGCGGAAGTACCATGCTAGTCGTCAATCAAAATCAACTATATAATGATGGGGTTCAGAAGAAATCGCCAATTCCGTATCTACCCCCAAATCAAAGTTTGGTACTGCGTCGTGATTCAGAAGATAAGTTGAGAACTTTGACGTCCTCTGGGGCGCCACTAGTCAACTTGAAAACACCGTCTCAGACCCATAATGGGGGCAACTCACAAACTCTGATTTACAACCAACCGATCATAAAGAAGATAATCCTAAACCCAACGTTCTTGCAATCTAATTCCTCACAGAATGTTACCTTGGTACCGTTAATGTCCGGATCTGAGTTAAACCAAAGCGACCTGCCAAGTTTTCCCAAAATCAAGTTAATACCTAATAGTGGAGTGGTTCATTCCTTGCCTGAAACGTTCAGGTGCAAAATTTGTTCCCTAAGTTTCGAGACTCGTGGTAAGTTGAGAGGCCACATGTACGCACATAAAAAAAGGACGCACAAGTGCGATAAGTGTGGGAAATCCTTTCACGTGTTGAGTCGCCTCAATGTCCACAAGTTAATCCACACGGACGATCAGAAGTTCCCTTGCGACGTATGCGGGAAAATATACAAGTCGAAGCATTCGTTGAAGATTCACTCGTGCAGCAATATCATCCTGGAGAAGAATTTTAATTGTGAGGTGTGCGGCAAGAAATTCTACAGAGAGCAACAGCTTAAAAACCACGTCAACACGGAGCACCTGAACATGAAATACAAATGTGACGTTTGCAAAAAGGAATACCGTCAGATCTTCACGTTGAAAATGCACAAGCGCCAGCACGACCCCCATTTCGAAGCCATGTCGTTAAAATGCGACCAGTGCGATGCGAAATTCACGTACAAGACCGCCTTGAGGAAGCACAAGTTGAGGGTGCACGTGGGTAAGCTGTACATGTGCGATATTTGCGGCAAGGAGATAACTTCCTCGACTAGTTTCCAAAGTCACCTGAGGActcacaccggcgagaaaccgttcgtgTGCGAAATTTGTGGCAAAGCGTTCGCTTCAAAGCCGTTGCTGAGAATACACGTTCGTATACATACTAAAGAGAAACCGTATCCGTGCAAGTTATGCGGCAAGAGATTTTCGCAGGTGGGTTCGGTGACGATTCATGTACTGAGAGTTCACCGACGCGAAAAGCAATTTCAATGCAACATCTGCAGTAAAAAGTATGTGTCCAAAGTTCAGTTGAAGGCCCACACGAAATTACACGGCATTCCTTTATCTGAGTTGGGAACTGATAGGGAAGTTGAAAAACCACCTAAACGCTAA
Protein Sequence: MISRILEITGFIYSLELEQFRVLTKGVCTLYIKIPVIIRTFKPEVNSKGKRIFSKPVTPDIIRLPLIEDFVKTRTKLVGESARNEIKKLLVYREHSYSKFKCRVGRVTCSECGTVFRTAYGLKMHKRFKHRAKPYACKQCELFLSTFLKTENLEDWSRYNIFLKRKRRRDSKMARKKMRKGKWECKKCNAVFDLVKQLRQHRKEHRLKPDEVKYNYTYNKTEDTYSCNTCDSEANTREEMEKHVQLHEDTYICQSCKSSFETAYNYALHLCPKSEDGAFKCPLCDFKTLRRPTIRKHINSMHFNKFIYYCSFCGKGIDDVLNFREHEATHLQSGKKQFSCVVCAKEFSFSRYLLTHQIRTHKANIEGIILPNQCPICKKNFAKRVSVDNHMLKHDLTLPLEKKHLCDICGKGFVRKDKLKIHYRVHTGIKPYTCSYCAKSFIKKDYLIMHERIHSGEKPYACEYCGKCFNQGAPLRIHVRIHTGERPSPETRRRVRWTPDSLIKALNLVKTGKSIRVAARISNVPYSTLQGRLQQGNFVAPRLGRRTVFNPEQEEDIAAQIRYLSNFFYGFTGIEIRKMAYEYARKNNIKHNFNETFEIAGIDWLRGFLRRNNLPVRRSEGVGLNRRAAPKEEEVKSFFALLKDLMDKHKFQAKGIYNASEIGIAPDKMLSGERSNLTAMCAMSAEGTYVPPMFIYPRKRHSTTLERNGPTGAKYACSRDGQINENLFLTWLKHFAKNVKPSEGDPVLLILRNRASKFSLRAYDFCQENHIVMLSIPPRGVQPLAVSFFASLRAAYIERCNLFRQLQAGREITHADIASLFKEAFESVASPDKAEIGFLATGIHPVNPKVLNEPGFLPVDVLKNSAFLECMEEYKLVNRKSMVKYYKVLLKSVNQVTKKVVEQTYLIPESSLSPDIRKRFRRTEESNPKAQTQPFIPNVALGQHLKSTLLASLKDKTLTSRQSQNLIIMGATSRDNAQNQQNVVASRNNTQSLLIRKFPSLRQFQGGIVGSVRSNSQAQKLPASPHFPEALRRTQKVNFNSLTCYQNKIQGVTSGSTMLVVNQNQLYNDGVQKKSPIPYLPPNQSLVLRRDSEDKLRTLTSSGAPLVNLKTPSQTHNGGNSQTLIYNQPIIKKIILNPTFLQSNSSQNVTLVPLMSGSELNQSDLPSFPKIKLIPNSGVVHSLPETFRCKICSLSFETRGKLRGHMYAHKKRTHKCDKCGKSFHVLSRLNVHKLIHTDDQKFPCDVCGKIYKSKHSLKIHSCSNIILEKNFNCEVCGKKFYREQQLKNHVNTEHLNMKYKCDVCKKEYRQIFTLKMHKRQHDPHFEAMSLKCDQCDAKFTYKTALRKHKLRVHVGKLYMCDICGKEITSSTSFQSHLRTHTGEKPFVCEICGKAFASKPLLRIHVRIHTKEKPYPCKLCGKRFSQVGSVTIHVLRVHRREKQFQCNICSKKYVSKVQLKAHTKLHGIPLSELGTDREVEKPPKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00464732;
90% Identity: iTF_00464732;
80% Identity: iTF_00464732;