Basic Information

Gene Symbol
-
Assembly
GCA_963555665.1
Location
OY743091.1:1460252-1461781[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.31 27 6.1 0.4 3 23 63 84 62 84 0.95
2 12 3.4 2.9e+02 2.9 0.3 1 23 107 130 107 130 0.88
3 12 0.0031 0.26 12.4 0.7 2 23 154 175 153 175 0.96
4 12 0.068 5.8 8.2 0.4 2 21 180 199 179 200 0.93
5 12 0.14 12 7.2 0.1 1 23 241 264 241 264 0.95
6 12 0.22 19 6.6 1.0 2 23 290 312 289 312 0.95
7 12 0.0025 0.22 12.7 0.3 2 23 336 357 335 357 0.94
8 12 5.8e-05 0.005 17.9 0.0 1 23 361 384 361 384 0.97
9 12 0.0012 0.1 13.7 0.8 1 23 388 411 388 411 0.98
10 12 1.1 95 4.4 0.6 1 23 416 441 416 441 0.89
11 12 0.072 6.2 8.1 5.4 1 22 450 471 450 473 0.88
12 12 0.0011 0.094 13.9 1.6 1 23 483 506 483 506 0.96

Sequence Information

Coding Sequence
atgacatggttcttttcttttttaggACCCACAAAGGATATTGACGGACTAACAGAGAAAgagagaaaacaaaaaaaagggtTATTTGAAAGATCCGTTAAACATAACCCACAGCGACGTAATGCTGTATTGATTCTAAGGCATTCCTCGGCCATTCCTTTTAAAACACGATTTAATAGAATACTTTGCTCGTATTGCCATGATGAATTTGAACCTATGGATGCTCTCAGAGTCCATATCAAAGACAAACACACGAATGCCGATTTTAACAGTGCTTTCTATAAAGTTGTTGATGACCTCAAAATTGATATAAGCCACTTCAGATGTAATTTATGTTCTCAAGATATAGAAAATGTTGAAAGATTTATGATTCACTTATCTCGGGAACATGGCAAATCAGTCAATTTCGAAGTACCTTTTGGTGTTTTACCTTATAGACAAAATGAAACCGGTGCATGGATGTGCCTGCATTGCGAAAAAGTTTATCCTGAATTCTCCCAAATGAACGGCCATTTACGAACTCACGCTAAGATATCTACTTGTGATAAATGCGGGGCTACGTTTCTCTCCGAACATGGACTTAAACAACACGAGCGAAACTTTCAATGTTACAAAGCCACCTATAAGCCCCGATTTGGCAAAGCATTGAAACATAAGtttaatactgaaataatCTTACAGTGTTCAACAGCATGTCCCTTCAGGACGTGGGGTCAAAATTTTAACTGCGTTTTTTGTCGAGTTCAATCCAATGATCCAAATGGCTTGCGGGCTCATATGGCATCAAGGCACGCTAATTTTGATATCCAACTTGTATTTAGTAGAAAATTGCGAAAGGAATTTCTAAAAGTTGATATAACAGACTTACAATGCAAACTTTGCTTCATGCACATTGATACATTGGACGATCTTTTGACGCATCTCAAAAATGACCACAAACAACCGGTGAACGTGGACGTCCAGCCTGGAGTCCTtccgtttaaattaaatgatggCTCCTGTTGGAAGTGTGCTATATGCAAGATACAATTTTctgattttatatcattaaaaaaacacacagCAGAACACTATCAAAATTATGTTTGTGACACCTGCGGAGAAGGTTTCATAACGGAAGTCGCCCTCCGAGCGCACACGAAGATACCTCACGACAATAAATACACTTGTAGCAGATGCGTCGCTACATTTTCAACTTTAGAAGAGAGGAACATACACATGAAAACACAACATACTAACCTTCCTTATATGTGCACTTACTGCAAGGACAAGCCGAGGTTCGCAACATGGGAGCTTAGAAAGCggcatttatatgaaattcataattataaatctggGGCGGAAATGTATGAATGTACCACTTGTCATATGATGTTCAAGACGCGGTCCCAGAAATATCATCATAACGTTAAAGTACATAGAACAAAGAAGGAAATTGATTTTGGATTCTCTTGCGGTCACTGCGCTAGAGGATTCACTACAAAGCTCTCTTTGGACAGACATAtagcaaaaaaacattttcatgtcTGA
Protein Sequence
MTWFFSFLGPTKDIDGLTEKERKQKKGLFERSVKHNPQRRNAVLILRHSSAIPFKTRFNRILCSYCHDEFEPMDALRVHIKDKHTNADFNSAFYKVVDDLKIDISHFRCNLCSQDIENVERFMIHLSREHGKSVNFEVPFGVLPYRQNETGAWMCLHCEKVYPEFSQMNGHLRTHAKISTCDKCGATFLSEHGLKQHERNFQCYKATYKPRFGKALKHKFNTEIILQCSTACPFRTWGQNFNCVFCRVQSNDPNGLRAHMASRHANFDIQLVFSRKLRKEFLKVDITDLQCKLCFMHIDTLDDLLTHLKNDHKQPVNVDVQPGVLPFKLNDGSCWKCAICKIQFSDFISLKKHTAEHYQNYVCDTCGEGFITEVALRAHTKIPHDNKYTCSRCVATFSTLEERNIHMKTQHTNLPYMCTYCKDKPRFATWELRKRHLYEIHNYKSGAEMYECTTCHMMFKTRSQKYHHNVKVHRTKKEIDFGFSCGHCARGFTTKLSLDRHIAKKHFHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01360094;
90% Identity
iTF_00420041;
80% Identity
-