Dros058496.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diplolepis rosae
Gene Symbol
topi
Assembly
GCA_030998225.1
Location
JAPYXD010000752.1:4501632-4504998[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.7 2e+02 4.5 1.5 1 23 246 268 246 268 0.90
2 16 1.5 4.4e+02 3.5 1.1 2 23 276 298 275 298 0.81
3 16 0.018 5 9.6 0.3 2 21 305 324 304 325 0.92
4 16 5.4e-05 0.016 17.5 0.8 1 23 332 354 332 354 0.96
5 16 2.9e-06 0.00084 21.5 2.8 1 23 360 382 360 382 0.96
6 16 0.00017 0.05 15.9 1.2 2 21 394 413 393 415 0.93
7 16 1.8 5.3e+02 3.2 3.1 1 23 430 452 430 452 0.96
8 16 8.3 2.4e+03 1.2 0.2 1 7 458 464 458 473 0.75
9 16 0.82 2.4e+02 4.3 1.8 1 22 490 511 490 514 0.89
10 16 0.13 37 6.9 0.4 1 21 527 547 527 548 0.94
11 16 7.6e-05 0.022 17.0 0.2 1 23 553 575 553 575 0.99
12 16 2.2e-06 0.00062 21.9 3.1 1 23 581 603 581 603 0.98
13 16 0.00011 0.031 16.5 0.5 1 23 609 632 609 632 0.97
14 16 0.053 15 8.1 0.7 1 23 638 660 638 660 0.89
15 16 2e-07 5.7e-05 25.1 1.1 1 23 666 688 666 688 0.99
16 16 6.7e-06 0.0019 20.3 4.9 1 23 694 717 694 717 0.96

Sequence Information

Coding Sequence
atgataagaGCAGATTCGATGAGTACAATGAGTGGTGATGATACTGGGATGGAAACTGTTGAAGGATCTATTATCTGGTCCCAGGACGATGCATTTTCTTCCAGTGAAATCTGGCAATTACAACCAGAACCAGAAAGCAACTCTTTTTCTCCATTATGTCGTTTATGCGCTGGTTTAGCAGAAAATCCTGTTTATATTTATTCCGAAATTGGAGAATCCATGAAGCTTGATCATAAAATCAACACATGTCTTAGTGTTAAGGTGAGGAAGACAGATCCTCTTCCAAAACAACTCTGCACCATTTGTGTGGAAAAAATCAACTGGTGCGACGAATTTGACTGTCAGTGCATTAAAGCAGAAGATACTctatcttcaatttttaaagaaaaacagACTTTTGAAAACTCAGAACAAATAACGAACGAGATAATTTGCGATGAGAAATCTTGTCCACTCTGTCTCGAAGGTAAAATGTCCACAAACCAAAGTAATGTAATTTCTCAGAGCCTCAGCCTCTACGAATCGGACATAATCATCGAGAGCAGCGACGAAGAACGAGTTCTCACCAATCTGAACATCGACCAGAAATCCTCTGAAAATTCCTCAATCATTTTTCAGTATCTAGGCAACTctgaaaaatatctaaaatgtACAGCTTGCATGAACCTCTACCATACAAAGGAAACTCTTGATAATCATAAATGCAAGCCTCCAACTCAAAATACTTCTAAAACCTACAAATGTACTTTATGCGAAGCTAATTTCTCGTTTGAGGAACGCCTGAATTTTCATCTTCAATTTCACAATAATATAATGAAACCTCTCTATTGTGAAATCTGCAAATTGACCTTTcctaaagaattaaaattgtattttcattataaaagaTATCATTGTGAAGATCAGGCTGTGTCTTGTCTTCAATGTGGGCAGCTTTTCCAGAGACAGGAAGAGCTTAAAGTGCACGTATGTGTTGATGCAAAAATAAGGCCTCACATTTGTGAGGTTTGCAATAAAGGATTTTCTGATGGATACACTTTAAAAAGACATGTTGTAACTCATCTTCCAGAGAAACCTTATAAATGTAATCAGTGCTCAAAGAGCTTTACTCAAAAGTCAAGGTTGAATAAGCATTTAGATGGTCATAAGATAATTATCCAGAGTTCTCAAATTCTTTGGAAATGTAAGGAATGTGGAAAGGTCTTTGCTTCTAACGAGGAAGCTGAAAAACACCTGAAATGTCATGACGAGACTGGAGAAGTTGAGGAAACTGTGGCTTCAAAGATATTCCAGTGTGAATTCTGCAACAGTTATTTTGTAGAGACTGAAGTTTTGAAAACTCATCGACATCAGCATCTTCTTGAGAAGCCGTATGAGTGTGAGGATTGTGAAATTGTTCACAAATCGTTCACTGAAGCTGTTCTAGATTGGAAGCAACATTCGAAAGGTTTCAAGGTCCAGATATACTTCATTTGTGAAAGTTGCAATAAAGAAATAAAGGAACTTTCCCTTCTTTATACACACTACCATAAAAGACTTCACTATCTTCCAAGGCCGACAGAATctggaaattcaaaatttgcTTGTGAATTTTGTGGATCAATTTTCAACGAGTTCGAAGAAttcaaaaatcataaaagagAACAGTGTTCAAAATTCAAATGCGATATCTGCGGAAGTTCTTTGCCCACTGCTAATTCCCTAAATGCTCATAAAAGACGTCACAATGGATTAAGACCCTACGTATGTAATATTTGTGGAAAAAGTTATACTCAGTCTAGTCACATGTGGACTCATAAAAGATTCCACATGGGAGTGAAACCCTACGCCTGTGAATATTGCGATCAGAGATTTACAATCAAACCTGATCTGGCTGATCATAGGAGGAAAAAACATACAAGGGAAAGACCTTTTAAATGCGATGTTTGCAACAAAGCTTTCCTTACTGGATCGGTTTTTTATCAACATAGACTAATTCACAGGGGAGACAGAAGATACAAGTGTAATTATTGCCAGAAAGCTTTTACAAGAACTGAAGCTTTGAATAATCATATTAAGATTCATACTGGAGAGAAGCCTCATGCTTGTGATGTTTGTGGTAGATGCTTCAGGCAAAAGGGTGATATGAGGAAACATAGGAGGACTCAACATTCTGCTAAAGAAATGGAATTGTAG
Protein Sequence
MIRADSMSTMSGDDTGMETVEGSIIWSQDDAFSSSEIWQLQPEPESNSFSPLCRLCAGLAENPVYIYSEIGESMKLDHKINTCLSVKVRKTDPLPKQLCTICVEKINWCDEFDCQCIKAEDTLSSIFKEKQTFENSEQITNEIICDEKSCPLCLEGKMSTNQSNVISQSLSLYESDIIIESSDEERVLTNLNIDQKSSENSSIIFQYLGNSEKYLKCTACMNLYHTKETLDNHKCKPPTQNTSKTYKCTLCEANFSFEERLNFHLQFHNNIMKPLYCEICKLTFPKELKLYFHYKRYHCEDQAVSCLQCGQLFQRQEELKVHVCVDAKIRPHICEVCNKGFSDGYTLKRHVVTHLPEKPYKCNQCSKSFTQKSRLNKHLDGHKIIIQSSQILWKCKECGKVFASNEEAEKHLKCHDETGEVEETVASKIFQCEFCNSYFVETEVLKTHRHQHLLEKPYECEDCEIVHKSFTEAVLDWKQHSKGFKVQIYFICESCNKEIKELSLLYTHYHKRLHYLPRPTESGNSKFACEFCGSIFNEFEEFKNHKREQCSKFKCDICGSSLPTANSLNAHKRRHNGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHRRKKHTRERPFKCDVCNKAFLTGSVFYQHRLIHRGDRRYKCNYCQKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHSAKEMEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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