Dlae013446.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diplazon laetatorius
Gene Symbol
PRDM1
Assembly
GCA_963662125.1
Location
OY759163.1:5145925-5152313[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 2.1e-05 0.0016 18.7 2.5 1 23 782 804 782 804 0.99
2 5 6.3e-06 0.00049 20.4 5.1 1 23 810 832 810 832 0.98
3 5 1.3e-06 9.8e-05 22.6 4.2 1 23 838 860 838 860 0.98
4 5 0.00084 0.065 13.7 1.5 1 23 866 888 866 888 0.97
5 5 5.6e-05 0.0043 17.4 0.2 1 22 894 915 894 915 0.96

Sequence Information

Coding Sequence
ATGGAGTCCAGCGAGTGGGATCACACGACCTTGACGGAAGAAGAATTCGAACAGCATGCGGTTTATTTGGTACCGGACGTATCGGCGACCCCGACCGATCCCAATCGTGCCGAGGGCTCGCTACCCCGAAATCTCGTACTCAAGCCCTCGCCCTCGCAATCGTCCAATGACGTGTTGGGCGTTTGGAGCACGAGTTACATTCCCAAAGGAACGCGTTTCGGTCCTCTGGTCGGACAGGTCTACACCAAGGACTCGGTGCCGGCCGACGCCAACCGCAACTACTTCTGGAGGGTGTACAAGGACAACGAACTGTTCTACTACATCGACGGTTACGACGTGCAAAAATCCAATTGGATGCGATACGTTAATCCGGCATATTCATCGACGTCGCAAAATCTCATAGCTTGTCAATATAAGatgcacatttatttttacaccGTGAAACCGATTCTGCCGAATCAAGAGCTTCTCGTGTGGTACTGCCGTGAATTTGCCGAGAGGCTCGGCTATCCACTGTCCGGCGAACTCATGCTACAACAAATACGACAACAAGCCGAGCAATCGACCCTGTCAACGGAAATCCCAGGTGTCCTGGATGTCGTTCCCCTGAAAGACACCTCGATCTACGAGAGACGTTGCCAAATGACGCCGACCGACGGTTCCGTGAGATCGGACGAGGGTTATCACTCCAACGGTTATCACGACGAGATTCTAACCCCACCCGAGGAAAGCAGCGAATCCGATTCCGAAAACAATTACGTCCTAGATTTCAGCAAAACAACACGCACGACAACCACAACGACCGAAGTAATCAGCAAACAAGAGAGCGTCGTcataaaaaatgcatacaGAAAAGTTAAAATAAAGATTCCAAAAGTTTACACGAATTTTCAAGTTGGCAAAGTCGACATTGACATGGTCAAGGACAaggatgaattttcatcgggCACGGTTACCCCGGAAATTCAAATTCCCATTAAATCATCGTCACCGATAATACTGCAAAAACAAACGGTCATATCAAcgtcgaacgacgacgacgacgacgacgacatgGACAAAACTTCGATGTCAAAACCTTTCTACGAACCCGAAGCCAAAGGTCCGCCATTGCCGATTACCGGAAGATCGCCCTACGTCACAAGCCCGAGCAGTTCGATATTGGAAAACATATTGTTGCGAACCAACAACACcgacagcaacaacaacaacaacaacaccagtCACATGCACAATCACAATTccataaacaacaacaacaacaatcatcatcatcacaacaacaacaatcatcaCAATCCACACCAGAGTCACAATCACGGTGTATTCGCGAGTCATTTGGACACGGTGACCCCACCCCCATCCAGTCCAACCGAAATGGCGTATTCCTACAAAAAATCCCACAGATACGGCAACATTCTCCCGTGCAGTCCGGATTCCAGTTCGAACCTGCAGCATCATCAAGAAATCTGCAATCCAACGTCAACGGTCGTCAATTCCACGACCTCATCGACTTCCATGCTCCAAAGTCCAGGAAATTTGCACTCAACTAGTGGCAATCACAACACAGTTAATCAATCACATTCTTGCGCAAATTCATTGACAAATTCGTCAACGATTAATTCCACGCAATTGTTGACATCAACGACGATCGGTGTGCATTCGTCGACGACCATCAACAACGGTTTGGTGATAAAATCATCGAGAAAATTGAAGAGTCCGTCACCCGTCGATGTTGGAAATGCTACGACGAGTTCGCCAAATTCCACGACAACGTCGTCGATGATAGGACCGTCGACGATTTTGTACACGTCGACTGTGAACCCGGTTGACGTTGAACCGTCGAGTTCGATGTATCATCACAATGGTTCCAACGCTTCTGGCAATGTTGGAGTTATTTCGCCCGTTCACTCGCCGGCTTCTTATCCGTACGGGCTTTATCATCAAAATGGCACGATGATGCATCAACACGTTGCACCTTTGTCCATCAATTGCGGCGCGGCTTATTCGCCAACGCCATCGGGCAATATGGCGTACGATCGCAACGATGCCAGAAGACACGATGGTAATGGACATCAATTGCCAACTTCGTCGACCATGCAGATCGATGGAGATCAATCTAATCTCATCGCTGGAACGCATAATTTGCATCTCGGACATTATCCCGGTTTGACAATTCATCCGaattcaacgacgatgaaTTCGCGTTATTCACCGGCCAGCTCGTTGTCGCCCGATGATCACGCTTGCTCGCAAAGCGGTTCGCTCAGTCCGAATTCACAGGGTTCGAGGGGTTACAGATCGTTGCCTTATCCGTTGAAGAAGAAGGACGGAAAGATGCATTACGAGTGCAACGTTTGTTGCAAAACTTTTGGACAATTGTCGAATTTGAAGGTACATCTGAGAACGCATTCGGGCGAGAGACCGTTCAAGTGCAACGTTTGCACGAAAAGTTTCACGCAATTGGCGCATCTACAGAAACATCATCTGGTTCATACAGGAGAAAAACCTCACCAGTGTGAAATCTGTAAAAAACGATTCAGTTCGACGTCGAATCTGAAGACTCATCTGAGACTTCATTCGGGTCAAAAACCATACGCTTGTGACCTCTGTCCCGCGAAATTCACGCAATTCGTTCATTTGAAGTTGCACAAGAGATTGCACACGAACGAGAGGCCTTACACGTGTCAGGGTTGCGACAAGAAATACATAAGCGCCAGTGGTCTGAGGACACATTGGAAAACGACGAGTTGCAGACCCAACAACATCGAGGACGAGCTCGTTCTGGCCGCGGCTGTGGGCTCGCCGAGTTACTACTCCGAATACGGATCCGATGGTAATGTTGGCAACATGCAGAAGGAATGCGATTTGGATCACATGGACAATTACGAGAGGCGCAACGTCGTTCATGGTGCGCACTCGACGTCGCTTCACACTCTCGAAAATTCCGTGGGACGTCCGAGCGTAATAGAAACGTCTCAGCCCCACATAATCGAGTGCACATAA
Protein Sequence
MESSEWDHTTLTEEEFEQHAVYLVPDVSATPTDPNRAEGSLPRNLVLKPSPSQSSNDVLGVWSTSYIPKGTRFGPLVGQVYTKDSVPADANRNYFWRVYKDNELFYYIDGYDVQKSNWMRYVNPAYSSTSQNLIACQYKMHIYFYTVKPILPNQELLVWYCREFAERLGYPLSGELMLQQIRQQAEQSTLSTEIPGVLDVVPLKDTSIYERRCQMTPTDGSVRSDEGYHSNGYHDEILTPPEESSESDSENNYVLDFSKTTRTTTTTTEVISKQESVVIKNAYRKVKIKIPKVYTNFQVGKVDIDMVKDKDEFSSGTVTPEIQIPIKSSSPIILQKQTVISTSNDDDDDDDMDKTSMSKPFYEPEAKGPPLPITGRSPYVTSPSSSILENILLRTNNTDSNNNNNNTSHMHNHNSINNNNNNHHHHNNNNHHNPHQSHNHGVFASHLDTVTPPPSSPTEMAYSYKKSHRYGNILPCSPDSSSNLQHHQEICNPTSTVVNSTTSSTSMLQSPGNLHSTSGNHNTVNQSHSCANSLTNSSTINSTQLLTSTTIGVHSSTTINNGLVIKSSRKLKSPSPVDVGNATTSSPNSTTTSSMIGPSTILYTSTVNPVDVEPSSSMYHHNGSNASGNVGVISPVHSPASYPYGLYHQNGTMMHQHVAPLSINCGAAYSPTPSGNMAYDRNDARRHDGNGHQLPTSSTMQIDGDQSNLIAGTHNLHLGHYPGLTIHPNSTTMNSRYSPASSLSPDDHACSQSGSLSPNSQGSRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFKCNVCTKSFTQLAHLQKHHLVHTGEKPHQCEICKKRFSSTSNLKTHLRLHSGQKPYACDLCPAKFTQFVHLKLHKRLHTNERPYTCQGCDKKYISASGLRTHWKTTSCRPNNIEDELVLAAAVGSPSYYSEYGSDGNVGNMQKECDLDHMDNYERRNVVHGAHSTSLHTLENSVGRPSVIETSQPHIIECT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01364931;
90% Identity
-
80% Identity
-