Dlae001808.1
Basic Information
- Insect
- Diplazon laetatorius
- Gene Symbol
- ZFX_1
- Assembly
- GCA_963662125.1
- Location
- OY759153.1:329215-333955[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 1.4 1.1e+02 3.6 3.0 1 23 122 145 122 145 0.91 2 22 0.0098 0.76 10.4 7.8 1 23 225 247 225 247 0.98 3 22 0.013 0.99 10.0 1.6 1 23 256 279 256 279 0.96 4 22 0.018 1.4 9.5 2.8 1 23 283 306 283 306 0.96 5 22 0.025 2 9.1 1.4 1 23 321 344 321 344 0.96 6 22 1.3e-05 0.001 19.4 1.5 1 23 350 373 350 373 0.96 7 22 0.00071 0.055 14.0 1.7 2 23 379 401 378 401 0.94 8 22 0.033 2.6 8.7 7.0 1 23 406 428 406 429 0.96 9 22 0.00012 0.0097 16.3 0.0 3 23 437 457 436 457 0.97 10 22 2.1e-06 0.00016 21.9 0.6 1 23 463 485 463 485 0.98 11 22 4.8e-06 0.00037 20.8 0.2 1 23 491 513 491 513 0.98 12 22 0.0013 0.099 13.1 1.3 1 23 606 628 606 628 0.97 13 22 1.4 1.1e+02 3.6 3.0 1 23 665 688 665 688 0.91 14 22 0.0013 0.097 13.2 5.7 1 23 768 790 768 790 0.98 15 22 0.00044 0.034 14.6 2.6 1 23 799 822 799 822 0.98 16 22 0.077 5.9 7.5 3.4 1 23 837 860 837 860 0.95 17 22 0.00018 0.014 15.8 3.4 1 23 866 889 866 889 0.96 18 22 8.9e-05 0.0069 16.8 1.0 2 23 895 917 894 917 0.94 19 22 0.0061 0.47 11.0 2.3 1 23 922 945 922 945 0.97 20 22 2.1e-07 1.7e-05 25.0 1.5 2 23 952 973 951 973 0.97 21 22 2.4e-06 0.00018 21.7 0.9 1 23 979 1001 979 1001 0.97 22 22 4.9e-07 3.8e-05 23.9 0.4 1 23 1007 1029 1007 1029 0.98
Sequence Information
- Coding Sequence
- ATGGATCAGGAATCGCCGATTAACGAAATaaattggaaaaaatcgtgCAACCGGGCTCCGATGATGGACGATGATTACAAGGTCGAGATCGACCCGCTGCTGCAACCGTCGGAAATCAAGATCGAAGTCGAGGACGAACCGTTCCTGGCTACCGACGAAAATCGTCACGAAGAACCGAACGAATGGCCCACGTGTGACAATAGCGgtccaaaaatttcattgatggAAACGTTGAATCTCCACAGAGTCACGCACGATGACAATCGTGACGcgagaagaacgaaaaaatcggtaaaatccTCGGCCAAGTCGGTGAACGACGTGAAAACTCACAAACCTGATGCATCGTCGTCGGAATCACGATACAATTGCACGATCTGTGATTTCACATGCGCAAAACGTTCGATCTTCGTGACGCATTCGAAACGCGAGCACAAACGTGAAAAGCCATCGACGATCGTAAAATCCGACGTAAAATCGTTGCAACCGCGTTATCgcggaaacgaaaaatcgaagatgGTAACGCGTGAAAACGCGAACGAGCACGTTGACGGTGAACAACGTCGGGATTCGAAGCCACAAACTCGCGCGATCGACGATGCGGAAATCGAAAATTTGCCGATCGATCGGTCGACCGAtgcgagaatgaaaaaaaaaccgctcgTCCAAGCTTTCAATTGTGACACTTGTGATTTCAAATGCTCGAGAAAAAGCACGTTGCACACGCACGAACGTCGTCATCGTGGTTTCCACACGTTCGACGTTTATCACTGCGACGATTGCGATTTTCAAACACCGAGAAAACCAACATTGTCATCGCACATAACACGAAATCACAATTCCGTTTATCATTGCGACGATTGCGATTTCGTAACAACGAAGAAACCAACTTTGTACTCGCACATTTATCGCAAGCACAAACCCCCGAAAACCGTCGTCACGAACAATCCGaacgattattttcgttgcaCGCAGTGCGATTATCGTAACAAAAGCAAATACGCGCTGAATGTTCACGTTGCGCGTAAACACACGTACGATTACAAATTTACGTGCGAAATTTGtgcgaaaaaatacaaagtaaAAAGCGATTTGACGAATCACATGAGATTCAGTCATCGCGAACAACCGATCGTCTGCGACGTTTGCGGAAAAACCTTTCTCAACAGTCATTCGCTCTATCATCATCAAAAAGGTGCTCATTACAAATCCCAATTCAAGTGTCACGTGTGCAAACGTTGCATGGTGAGCCAGGAAAATTTGGACAAACACGTGTCGCGACATCACGAAAAACGCGACAACGTCGCGTGCGAGGAATGCGGCGAAATTTTTATCCGCGACGAACTTTTGAAACAACACATGCTCGTGCACACCGGTGAAAAACCTTACGATTGtggaatttgcaaaaaaacgtttgttcgtAGCAACGCGTTGAAGCAACATCTTCTCACTCACACGAATGTGCGTCCTTACGTCTGCGACGTTTGCGGCGAATCtttcaatcaaaaaaacgGACTCGCGAGCCATCGTAAATCACATCCGGGACCGCTTCCGCCGCTTCCGCGAGTACTCATCGATCCCATTCTTCACGACGTTCTCAGACCTGACACaaattggaaaaatgcgAGCGATCGGatttcgacgatcgacgacgatCACAAGGACGATCGTGGAAATGATGGTTCGTGGATACGATCGAGACTCAATGGGAACGAGGTCGACCCGCTGCTGCAATCGTCGGAAATAAAGATCGAAATCGTGGAACATAAATTACGAtctaccgaaaaaaatcgttacgaaaattccatcgaatgGCACAAGTGCGACAAATGCGGTCTTAAATTTCCATTGATGGGAATGTTGAATCGTCACAGAGTCACTCACGATTACAATCGTGACTCGagaggaacgaaaaaatcggttAAATCCTCGGCCAAGTCGGTGAACGACGTGAAAACTCACAAACGTGATTCATCGTCCGCGGAATCACGATACAATTGCACAATCTGCGATTTCACATGCGCAAAACGTTCGATCTTCGTGACGCATTCGAAACGCGAGCACAAACGTGAAAATccatcgacgatcgtcgaatcCGACGTAAAATCGTTGCAACCGCGTTAtcgcgaaaacgaaaaatcgaagatgGAAACGCGTGAAAACGCGAACGAGCACGTTGACGGTGAACAACGTCGAGATTCTAAGCCACAAACTCGCGCGATCGACGATGCGGAAAGCGAAAATTTGCCGATCGATCGGTCGACCGAtgcgagaatgaaaaaaaaaccgcttgtccaaattttcaattgcgACACTTGCGATTACAAATGCTCGAGAAAAAGCACGTTGTACACGCACGAACGTCGTCATCGTGCGTCCCACACGTTCGACGTTTATCAATGCGACGATTGCGATTacaaaacaacgaagaaacaaacatTGTACTCGCACATAAATCGCAAACACAAAACCGTGAAAATCCCGATTACGAACAACtcgaacgattattttcattgcaatcaGTGCGattatcgaaacaaaaacaaatacgaGCTGAAAGTTCACGTTGCGCGAAAACACACGGACGATTACAAATATTGTTGCGACGTTTGtgcgaaaaaatacaaagtaaAAAGCGATTTGACGAATCACATGAGATTCAGTCATCGCGAACAACCGATCGTTTGCGACGTTTGCGGAAAAACGTGTTCCAACAGCAATTCGTTGTACGTTCATCAAAAATTTGCACATTACAAATCGAAGTACGAGTGTAAGATGTGCAAACGTTGCATGGTTAGCCAGGAAAATTTGGACAAACACGTTTTGCGACAACACGAAAAACGTGAGAACGTCGTTTGCGAGGAATGCGGAAAAACTTTTACCCGCAATCATCGTTTGAAGATACACATGCGCATACACACGGGTGACAAACCTTACGATtgtaaaatttgcaaaaaaacgtttgcccGTAGAAACGCGTTGAAGCAACATCTTCTCATTCACACGGGCATGCGTCCTTACATGTGCGACATATGCGGAAAATCTTTCACCCAAAAACCCGGACTGATAAGCCATCGTAAATCGCATCCGGGACCGCTTCCGCCGCTCTCGCGTGTTCTCATCGATCCCATTCTCAACAACGTTCTCAGTTCTGCTTCGTGA
- Protein Sequence
- MDQESPINEINWKKSCNRAPMMDDDYKVEIDPLLQPSEIKIEVEDEPFLATDENRHEEPNEWPTCDNSGPKISLMETLNLHRVTHDDNRDARRTKKSVKSSAKSVNDVKTHKPDASSSESRYNCTICDFTCAKRSIFVTHSKREHKREKPSTIVKSDVKSLQPRYRGNEKSKMVTRENANEHVDGEQRRDSKPQTRAIDDAEIENLPIDRSTDARMKKKPLVQAFNCDTCDFKCSRKSTLHTHERRHRGFHTFDVYHCDDCDFQTPRKPTLSSHITRNHNSVYHCDDCDFVTTKKPTLYSHIYRKHKPPKTVVTNNPNDYFRCTQCDYRNKSKYALNVHVARKHTYDYKFTCEICAKKYKVKSDLTNHMRFSHREQPIVCDVCGKTFLNSHSLYHHQKGAHYKSQFKCHVCKRCMVSQENLDKHVSRHHEKRDNVACEECGEIFIRDELLKQHMLVHTGEKPYDCGICKKTFVRSNALKQHLLTHTNVRPYVCDVCGESFNQKNGLASHRKSHPGPLPPLPRVLIDPILHDVLRPDTNWKNASDRISTIDDDHKDDRGNDGSWIRSRLNGNEVDPLLQSSEIKIEIVEHKLRSTEKNRYENSIEWHKCDKCGLKFPLMGMLNRHRVTHDYNRDSRGTKKSVKSSAKSVNDVKTHKRDSSSAESRYNCTICDFTCAKRSIFVTHSKREHKRENPSTIVESDVKSLQPRYRENEKSKMETRENANEHVDGEQRRDSKPQTRAIDDAESENLPIDRSTDARMKKKPLVQIFNCDTCDYKCSRKSTLYTHERRHRASHTFDVYQCDDCDYKTTKKQTLYSHINRKHKTVKIPITNNSNDYFHCNQCDYRNKNKYELKVHVARKHTDDYKYCCDVCAKKYKVKSDLTNHMRFSHREQPIVCDVCGKTCSNSNSLYVHQKFAHYKSKYECKMCKRCMVSQENLDKHVLRQHEKRENVVCEECGKTFTRNHRLKIHMRIHTGDKPYDCKICKKTFARRNALKQHLLIHTGMRPYMCDICGKSFTQKPGLISHRKSHPGPLPPLSRVLIDPILNNVLSSAS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -