Dvan002797.1
Basic Information
- Insect
- Dione vanillae
- Gene Symbol
- ZEB2
- Assembly
- GCA_037178615.1
- Location
- JAZFAU010000029.1:4631360-4633069[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0007 0.078 14.5 0.3 2 23 145 167 144 167 0.92 2 9 0.0061 0.67 11.5 6.0 1 23 185 207 185 207 0.98 3 9 7e-06 0.00077 20.8 2.9 5 23 216 234 213 234 0.96 4 9 4.2e-06 0.00047 21.4 3.9 1 23 240 262 240 262 0.97 5 9 0.0014 0.15 13.5 1.5 1 23 267 289 267 289 0.98 6 9 2.9e-06 0.00032 22.0 3.0 1 23 295 317 295 317 0.98 7 9 0.003 0.33 12.5 4.5 2 23 324 345 323 345 0.97 8 9 8.1e-06 0.00089 20.6 2.8 1 23 351 373 351 373 0.99 9 9 2.2e-06 0.00025 22.3 2.9 1 23 379 402 379 402 0.97
Sequence Information
- Coding Sequence
- ATGGAAGTAGAACAGCCTATTATGAAGACACTGGACGCAAATATTTGTCGGATATGTTTACGAAATGAACAGAATTCTATAGGACTTTTTACTGCTGAGAAGGATTCTacggaaatattaaaaaagatttatgtTTGTTTTCAAATAACATTAACATATAAAGAGAATTTTCCCTCGTCTATATGCACTACTTGCATGAGAGACCTAAACATGGCTTATAATTTTCGTCAAAATTGCGAAACCTTcgaaaaacgttttattttattccaagATACTGCTACAGAAACTAAAGCTCctactaattattttagttatatggaTCGTTCAAAATTAGacagtaaacataaaaatgataaatgtgaaaatattacatttcatgAAGgTGATGGTAAACCAGCTAATGACATCgcaaatgattataataaatctttaatgtGTTCCATATGCAAAAAAGTTCTTAAGTCAGAAGCTTCATTGACTAAACATACTGTTTCTATgcatcaaaaaagaaaaaatcatggTAAAGTTTCAGGTTTTGGTATTAATCGTCGGTATCATTGTACTAAATGTTCATACAATACACCTCACAGTCAAACACTAGTAAATCATATGAGAAAACATAGCGGTGATCGTCCTTTTCAATGTGAATGTGGCAAATGCTTTACACAATCATCAAGTTTGAATGCACATCGTAAAACACatagtaatacaaaatattttacttgttcCAAATGTGGAAAGCAATTTAAACATGCATTTTCATTAAAGAAACATTTAGATGTACATGAAAAGGGCAAATTTAAATGTGATATATGCCTCAAGCAGTTGAAATCGAGACAAACTTTACAAGACCATATATATCGTCATTATAATGTGAAGAATTACAATTGCGAAGATTGTGGGAGGACCTTTGTAACTTGTTCTGAACTACTAAAtcataaaaagaaacataatgCAGTCAAGAATATGGAATGTCACTTATGTGGATATAAAACACATACTAAAAAAAGTTTGATTATTCACTTGAAGCGACATGCTGGGGATAAGTCTTACAAGTGTGATCTATGCCATGTGTCCTTCTTCACTAATGGAGACTTGCAACGTCATAAGCGAGTGCACACGCGAGACAAGCCTTTTCCCTGTCCAACTTGTACACAAAGGTTTACACACAGCACAAGTTTAAACAAGCATATGAAGTCAGTGCATGGCATAGAATGTAAGTGGGCAGACATTAAAATTAAGAACTTGACATAA
- Protein Sequence
- MEVEQPIMKTLDANICRICLRNEQNSIGLFTAEKDSTEILKKIYVCFQITLTYKENFPSSICTTCMRDLNMAYNFRQNCETFEKRFILFQDTATETKAPTNYFSYMDRSKLDSKHKNDKCENITFHEGDGKPANDIANDYNKSLMCSICKKVLKSEASLTKHTVSMHQKRKNHGKVSGFGINRRYHCTKCSYNTPHSQTLVNHMRKHSGDRPFQCECGKCFTQSSSLNAHRKTHSNTKYFTCSKCGKQFKHAFSLKKHLDVHEKGKFKCDICLKQLKSRQTLQDHIYRHYNVKNYNCEDCGRTFVTCSELLNHKKKHNAVKNMECHLCGYKTHTKKSLIIHLKRHAGDKSYKCDLCHVSFFTNGDLQRHKRVHTRDKPFPCPTCTQRFTHSTSLNKHMKSVHGIECKWADIKIKNLT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00778196;
- 90% Identity
- -
- 80% Identity
- -