Basic Information

Gene Symbol
ECU03_0790
Assembly
GCA_963930735.1
Location
OZ005740.1:237199615-237217429[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.027 13 9.1 3.5 3 19 114 130 112 133 0.92
2 12 0.026 12 9.1 2.5 2 23 144 165 143 165 0.90
3 12 0.0029 1.4 12.1 0.1 3 23 174 195 173 195 0.95
4 12 4.7e-05 0.022 17.8 1.0 1 23 201 223 201 223 0.97
5 12 0.00049 0.23 14.6 0.9 1 23 229 252 229 252 0.97
6 12 2.8e-06 0.0013 21.6 1.4 1 23 257 279 257 279 0.98
7 12 0.086 41 7.5 0.1 2 23 289 310 288 310 0.96
8 12 0.065 31 7.9 1.5 1 23 328 350 328 350 0.97
9 12 0.0007 0.33 14.1 1.9 1 23 355 377 355 377 0.98
10 12 0.1 47 7.3 1.2 1 23 393 418 393 418 0.96
11 12 0.21 1e+02 6.3 1.0 1 12 424 435 424 436 0.92
12 12 0.048 23 8.3 0.2 1 23 437 462 437 462 0.96

Sequence Information

Coding Sequence
ATGACTATACAAACCAATGATTCAGAAGAGTTTGAGCATGTTGATTATTTAGATGAATATGATGAGAAAATTGACTTCAAGGAGTACAAAACTAAAGTCTTGCGTAGCAAGTTTTTAGATATTGTTTTTCCAGAATATATTAATTGCCGGATTTGTTCGGACACTTTAAATAAACATGTGGATATAATAGTGCACACACAAAAGGTGCACTGCGTGGATGACTTTGCATATCCATGTGTTATAGATGAAAGCTGCGAGCCACTTGAATCAGCAGCGGACTTATCCTTCCATTTAGTTTTTAAGCATTACGATTTAGAAGCTTTAGTCATTTATTCACATTGCCCAGAATGTAATAGACGTTTCAATGACTACATGTCTTATAATAAGCATTCTTGCTATCGAGGAGATAAAATATCTCGCAGTGCAATAGAATGTGAAATATGCAGCAAAACATTTAAATCAAATAAGAGGTACCGCTTTCATCAACAATTCCATCAGGAAAAACGACGTCCAAAAGCTTGCCTTATATGTGATAAACTCTTTCGGGATGAAGATGAATTTTATGAGCACATTATGTATAGCCATGAAAAAGATCTGGGTTTTGTTTGTGTAAGTTGCGATTGTTCATTTACATCAGCCGAAAACTTGAAAAATCATGAGAATATTCACAAAATATACCGACCGTATCGCTGCAAAGTTTGCAATAAATCTTATTTATACAATCAGCTTTTGAATGATCATATGcTATCAATTCATGGAAAGAGCTTATTCGAATGTCATATATGTGGCAAGAGCTTGGTGAAGAAAACTCTTCTAAACAAACATATTTTATCCCATAATAAACCCCAACCGGCTGAGGTTACGAGTTGCAGTATATGTGGCTTAATTACCAATGAAGAAAGTCAAGCAGAAAACCATTTGAAAGAGCATGATGAAAGTGATGATGAACCAAAAACTAAAACCGAAGTTCTGGAAATAGCGTATTGCTGCGAATATTGTGAGTTGGCATATAATTCCATTGAAAACATGTTTGGTCATCGAAAATTACACAACAAAAAGGAATATTATTGCGATATGTGTCCCTTGTCTTATGATcagtacaaaaaattgaaaacacaTAAATTAACGCATCTTAATTATGTGGACAAAAGGTCAACCTTTCCTGTACTTAGATATTACGTCTGTGATGCAGAgGGCTGTACGATGAGCTATTTGCAATGGACTAGTTTAAGATCACATAAAAGGCATAAACATAACGACATGCAAGCATTTAAATGCCCTAAATGTTCGGAGACTTATAAGAATGCttttatatgcCCATATACAGGATGTAAGAGTTCCTATCCTAATCAAGGAATTTTAAATTCTCATATACGCTCAAAACATCAAAACTCTGATAATATgccaattaaacaaaaaaacgcTACAGATGTTGTTATCCGCTCTCAATTTTTGATACCGCCAGCTGATATTTtcattgatgatgatgatggcttGGATGACGGTGTAATAGGAGAGCCACAGTGCAAAAAGATAAAGACTGAGGAAGATGAAAATAGTTTCGACGATCCTACGCTTTATATTAATCACGAATCAGATTCAGAGCCCGCTGTAATTGTCCTGAAAAATGAATCGGATCACGATTACATTGTTCGCCTAGATGAAAACAAGATCTATGGAAATATTATTGAAGAGTATAAGGTAGAAGATGATTACACTGCATAA
Protein Sequence
MTIQTNDSEEFEHVDYLDEYDEKIDFKEYKTKVLRSKFLDIVFPEYINCRICSDTLNKHVDIIVHTQKVHCVDDFAYPCVIDESCEPLESAADLSFHLVFKHYDLEALVIYSHCPECNRRFNDYMSYNKHSCYRGDKISRSAIECEICSKTFKSNKRYRFHQQFHQEKRRPKACLICDKLFRDEDEFYEHIMYSHEKDLGFVCVSCDCSFTSAENLKNHENIHKIYRPYRCKVCNKSYLYNQLLNDHMLSIHGKSLFECHICGKSLVKKTLLNKHILSHNKPQPAEVTSCSICGLITNEESQAENHLKEHDESDDEPKTKTEVLEIAYCCEYCELAYNSIENMFGHRKLHNKKEYYCDMCPLSYDQYKKLKTHKLTHLNYVDKRSTFPVLRYYVCDAEGCTMSYLQWTSLRSHKRHKHNDMQAFKCPKCSETYKNAFICPYTGCKSSYPNQGILNSHIRSKHQNSDNMPIKQKNATDVVIRSQFLIPPADIFIDDDDGLDDGVIGEPQCKKIKTEEDENSFDDPTLYINHESDSEPAVIVLKNESDHDYIVRLDENKIYGNIIEEYKVEDDYTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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