Dfeb002518.2
Basic Information
- Insect
- Dilophus febrilis
- Gene Symbol
- grau_2
- Assembly
- GCA_958336335.1
- Location
- OY284468.1:18149677-18155086[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 1.2 69 4.6 0.7 2 23 51 73 50 73 0.96 2 19 1.2e-06 6.9e-05 23.5 1.0 1 23 105 127 105 127 0.98 3 19 0.00044 0.025 15.4 3.9 1 23 135 158 135 158 0.98 4 19 0.0013 0.073 14.0 0.5 1 23 166 189 166 189 0.96 5 19 0.0073 0.42 11.6 0.3 2 23 197 219 196 219 0.93 6 19 2.2 1.3e+02 3.8 0.7 2 23 228 250 227 250 0.92 7 19 0.00073 0.042 14.7 3.6 2 23 256 278 255 278 0.97 8 19 4.5e-06 0.00026 21.7 0.3 1 23 285 307 285 307 0.98 9 19 2.8e-06 0.00016 22.3 4.4 1 23 313 336 313 336 0.98 10 19 0.56 32 5.6 0.6 2 23 509 531 508 531 0.96 11 19 7.9 4.5e+02 2.0 0.1 6 23 540 557 540 557 0.94 12 19 0.0013 0.075 13.9 0.6 1 23 563 585 563 585 0.98 13 19 0.0011 0.061 14.2 3.7 1 23 593 616 593 616 0.97 14 19 0.00086 0.049 14.5 0.1 1 23 624 647 624 647 0.97 15 19 0.0021 0.12 13.2 0.2 2 23 654 676 653 676 0.95 16 19 0.16 9.2 7.3 1.0 2 23 685 707 684 707 0.96 17 19 0.049 2.8 9.0 0.9 2 23 713 735 712 735 0.95 18 19 0.00042 0.024 15.5 0.9 1 23 742 764 742 764 0.97 19 19 6.9e-06 0.0004 21.1 2.8 1 23 770 793 770 793 0.98
Sequence Information
- Coding Sequence
- ATGGATTTCATTTGTCGTTTATGCTTGACGAAATGTGAAGAatttattggtatatttaGTGAATACGGTAAAGAACAAAATATAGCCgcaataatatcaaaatatttttggtttgaGGAAGCCAAAGAAATGGGTcaatattttgaaatgaaatgtgAGTTATGTGAAAGAGTCTTAGAATCATTACCTGATGCCCATCAACATTATCGTCGTACACATAAAACTATGGGTTACTTAAAATGTTGTGGACGGAAATTTTTTAAACGTTGCCGAGCCCTGGAACATATTGCATATCATTTAAATCCAGACGTATTtagTTGTACAGGTTGTAACAAGTCATTTTTCGATAAAAGCGGTCTTAATAGTCATATGGAAATGCATGCACCAATTGAAtcaagaaaatataaatgcagtatatgtacattaacgtttgtaaaaaaatgtaaattaacaCAACATGAACGAACTGGTCATAGTGATATACagaagaaaaattttatatgtgatatttgtgataaatgTTATATAACCAAAGCAATTTTAGCTGGACATATTCGTCGTACCCATCAGGGGCGTTCCGTTTACCAAGTTTGTGATATCTGTGCAAGAACATTCAAAAGTAAAAAAGTATTAGAAGAACATCGCGGTCGGGCACATTTCAACATCATTGAACCACGTGTACAATGCACTATTTGTGGATCATgGTTGGCGCATTTAACGGCTTTGCGAAAGCATACAACAAGACAACACATAACTGATCCTCAGAAATGTACGCATtgtggaaaatttaaaaagaataagGATGCATTACGAAGACATATTAAATCTGCGCACCAACTTCTATCCGAAAAGTATAAATGCTCAATTTGTGAAAAAGCATTTAAAAAGTCAATTGCATTAAAGGAACACATGGCATCGCATACCGGTCAGTTTTTATATACTTGTCCACATTGTCCGAAAACATTCAATTCAAATGCAAATTTGCATTCGCATCGTAAAAAAATTCATCCCGTGGAATGGGAAAATGCACGATTAAGGCCACAACACACTAATAGTGGAAAACAATTATTTGAATTCCCATTTATTGGTATATCATCAACAATATCAAATAATGAATATGCAGATTTTGACGAATCAAATCTTGTCATCAATAAGATTTCATCAAATCaatctattattattgataataataatacgattGATGTTAAAACAGAATGTTTCAATTTAAATGATCAGAATAATGCTGTCGATGGcaatgctgatgatgatgatgctttGGACGAAGATTATGATCCGATAGACGATATTAGTACAACAAAACacaaattgataaaaaaaacaaaaaccacaATTAGAAAACGTAAACttaaaaaatctaaaacagaaccaatagaaaaaaagaaatgtaataAACTTTCGGTAGATGAAAGATTAGCGTTAAGAAATGAAAAGTTAGAAAAACGAAATGTTAATCAAGAGAAATTCCAACAAGAAGCCAATGAAATGCGTCAATATTTTGATATGAAATGTGAATTGTGTGATGCTTTATTTGAATCGTTAACCGATGCCCATCAACATTATCGCGTTCAACATAATCATAAGGGCTATTTAAAATGTTGTggaagaaaatttttcaaacgTGGCAGTGCCCTGGAACACATTGCCTATCATTTAAATCCGGATACCTTTAAATGCACAATTTGTGATAAAAAGTACCTCGATAGAAAAGGTCTGGATAATCATATGGAAGTGCATGTACCAATTGAATCAAGGCAATTTAAATGTAGTATATGCACATTATCGTTtgcaaaaaaatgtaaattaaccCAACACGAACGAGTTAGTCATAGTGAAAAACAAGAAAAGATTTTCGAATGTGATATTTGCAAGAGAAGctataCAACAAAAGGAATTATGGCAGCCCATATACGTTCTATTCATCAAGCACCGGTATGTCTAGTATGTGATATGTGTgcaaaaacatttaaaagtAAAGCGGTTCTGGAAGAACATCGCTCCCGTGAGCACCTGAACATTGTTTTACCACGAGTACAATGTAGCATTTGTGGATCATGGTTAACGCACATAAGAGCTTTACGAAAACATATTCGACGACGACACATGAGTGAACCACAAACGTGTGTCCATTGCGGTAAACTTAAACCAAATAAAGATGCATTACGTAGACATATCACTTCTGTACATGTTCATACAACAGAAATGCATTCCTGTACAATTTGTGAGAAATCATTTAAACGGgcaattatattaaaaGAACATATGGCATCGCATACCGGTCAGGCTCTATATACATGTCCGTATTGTCCGAAAACTTTTAATTCTAACGCTAATATGCATTCGCATCGTAAAAAAATACATCGAACAGAATGGGAAAATGCGAGATTAAAACGTACTCTTCAGTAA
- Protein Sequence
- MDFICRLCLTKCEEFIGIFSEYGKEQNIAAIISKYFWFEEAKEMGQYFEMKCELCERVLESLPDAHQHYRRTHKTMGYLKCCGRKFFKRCRALEHIAYHLNPDVFSCTGCNKSFFDKSGLNSHMEMHAPIESRKYKCSICTLTFVKKCKLTQHERTGHSDIQKKNFICDICDKCYITKAILAGHIRRTHQGRSVYQVCDICARTFKSKKVLEEHRGRAHFNIIEPRVQCTICGSWLAHLTALRKHTTRQHITDPQKCTHCGKFKKNKDALRRHIKSAHQLLSEKYKCSICEKAFKKSIALKEHMASHTGQFLYTCPHCPKTFNSNANLHSHRKKIHPVEWENARLRPQHTNSGKQLFEFPFIGISSTISNNEYADFDESNLVINKISSNQSIIIDNNNTIDVKTECFNLNDQNNAVDGNADDDDALDEDYDPIDDISTTKHKLIKKTKTTIRKRKLKKSKTEPIEKKKCNKLSVDERLALRNEKLEKRNVNQEKFQQEANEMRQYFDMKCELCDALFESLTDAHQHYRVQHNHKGYLKCCGRKFFKRGSALEHIAYHLNPDTFKCTICDKKYLDRKGLDNHMEVHVPIESRQFKCSICTLSFAKKCKLTQHERVSHSEKQEKIFECDICKRSYTTKGIMAAHIRSIHQAPVCLVCDMCAKTFKSKAVLEEHRSREHLNIVLPRVQCSICGSWLTHIRALRKHIRRRHMSEPQTCVHCGKLKPNKDALRRHITSVHVHTTEMHSCTICEKSFKRAIILKEHMASHTGQALYTCPYCPKTFNSNANMHSHRKKIHRTEWENARLKRTLQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -