Dcae024662.1
Basic Information
- Insect
- Diloba caeruleocephala
- Gene Symbol
- Bcl11a
- Assembly
- GCA_947459985.1
- Location
- OX381618.1:3567269-3586883[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.015 1.3 10.2 5.2 1 23 275 297 275 297 0.96 2 12 5.1e-06 0.00042 21.1 1.7 2 23 305 326 304 326 0.96 3 12 0.07 5.8 8.1 0.4 1 23 330 352 330 352 0.97 4 12 3.3e-05 0.0027 18.6 2.5 1 23 357 380 357 380 0.97 5 12 0.001 0.082 13.9 0.1 3 23 386 407 385 407 0.96 6 12 0.006 0.5 11.5 0.1 2 20 423 441 422 447 0.92 7 12 0.0031 0.26 12.4 1.2 3 23 457 478 457 478 0.98 8 12 6.4 5.2e+02 2.0 1.2 2 23 494 516 494 516 0.91 9 12 0.093 7.6 7.7 2.6 2 23 528 549 527 549 0.96 10 12 0.0058 0.47 11.5 3.2 1 23 555 577 555 577 0.99 11 12 3.7e-07 3e-05 24.7 0.5 1 23 583 605 583 605 0.98 12 12 0.00057 0.047 14.7 1.0 1 23 611 634 611 634 0.98
Sequence Information
- Coding Sequence
- ATGGAAGACGTTAAAGTATGCCGTATTTGTTTAAATATGGATATAAAAATGCATGACCTGCATTCATACCCATTGGAATCATATTTTGCGTCAGTCTTGATCGATAGCAAGCCCTGGTTTACCACACAAATGCCACCATATGCCTGCTATGAGTGTGCAGCACTTGTGAAAAAGTTTTATTTTTTCAGGCAAAAGTGTCTACGTACTCAGGAAATACTCTGTGAAATAATAGATGATTGTGGGAAGATAACACATGCAGCAATAAGGGAAAATAAAAGAGAAAGTCTTCTTGTAATATCAAATCTCACGCATATTGATATCAAAGAAGAAAATGACATTGATTGCCTAAACATAGAGCCTGGATTTACTGTAGAAATTATAAAAAAAGAAGATCATGATAATGATGACATACCTGACAACACAATACCCAGTCCTAGTCAATCTAGTGATGATGAACATACAGAGAAGAATGATAAGGAGAAAATTAAGGATGTAGATATGGAGAAATTAGACTTTACTGTAAAGTTGAACATTAATGTGGAGTTGGAAGACCCTGAGTTGGCCCCAGCCACGGAAAATGAATCTGTATCAGTTCCGCCACCCAAAAAAACTCGTATGGCACAGCCAAAAAAGCGAAGCAGAACTAAGAAGACTGGCATGACAGTTGGCAAGAAGAAGGTGCCGAAAGTCGCTAAAGAAGACGGCCCATGCTCCGATGACAAGACTCAAATGGAAGATATTACTGTGGTTACGTTGTCGttggaagAGCAAATTGAAGAGATAAACAAGCGTAAGCAGTCGTCCAACTACCTGAACTGTCCATACCAGTGTCACTTGTGCTACAAGGGGTTCAATAACACACAAGCCTGGAAACATCACGTCACGAAGCATTCTCCCATCATAGGTGATATAGAGTGTACAATATGCAAGTACAGATTTAAAACCAAACGCAATCTTCAGAGACATGTACTGAACCATGGGAAGAAATATGTATGTAAATTATGTCCGTACAACTCGAGTAACATAACCACGGTGAAGCAGCATCAAGGTTCGCACAAAGGTATCACGCACAAGTGCAACTATTGTGATGAAGTCTTCACTGTAAGGACAACCTACGTGAGCCACATGCGCATCAAGCATCCATCGGAGAACATCTGCGGTTTGTGCGGTTACTCGTTTTACAGCAAGCAAGGTCTGCTCGTGCACAAGAATATGGTGCACAAAGATATACTGATAAAAGTTGAGGAAAACAAAGACGAAGGATTGTACTGTGCGGAGTGCGACGTCAGGTTCATATCAACGGAGGCGTTCAAGCGACACATGGTGATGTCCGTCAAGCACACCGAGAGTACAGACACTATTAACGGCTGTCGGGTATGCGGCGCAAAATTCTCGGGCCCTGAGAAACTACGTCTCCACCATCGCAAGGAGCACCCCGAGAAACAACCCAAGAATTACCGCGTGAACAAGTGGCCCGCCAAGTGCGAACATTGTTCGGAAGAGATGCCGAGTACGCGCGCGTATTTGAAACACTTCCGCCTCGTGCACCCCGAGGAGAACTACCCTCTGCAGAAGAAGTGCGTGTGCGACATATGTGGCAAACTTTTTATGTGCAACGCTCTCCTGGTGATGCACAAACGCACCCACTTCGGGGAGCGGCCCTACAAATGCTCCCAGTGCGATACAGCATGCTTCACTGGCTTCGACCTTCGCGTCCACCAACAGAAGCACTCTGATATCAGACCGTTTCCTTGCACCGTGTGTACTAAAGCCTTTAAGCGGAAAGAAGCGCTGGAGAGACACTTAAAAATTCACTCGGGCGATAATTTATACAAGTGTGAAATATGCGGCGTAGCGTTCAACAAGCCGTGCACGCGCACGCTGCACGTGCGCACCGAGCACGCGCGCGCGCCCGCTCCGGCACGCGCCCGGCGCATGCGCAAGCCCGCCGGCTGCGTCTGA
- Protein Sequence
- MEDVKVCRICLNMDIKMHDLHSYPLESYFASVLIDSKPWFTTQMPPYACYECAALVKKFYFFRQKCLRTQEILCEIIDDCGKITHAAIRENKRESLLVISNLTHIDIKEENDIDCLNIEPGFTVEIIKKEDHDNDDIPDNTIPSPSQSSDDEHTEKNDKEKIKDVDMEKLDFTVKLNINVELEDPELAPATENESVSVPPPKKTRMAQPKKRSRTKKTGMTVGKKKVPKVAKEDGPCSDDKTQMEDITVVTLSLEEQIEEINKRKQSSNYLNCPYQCHLCYKGFNNTQAWKHHVTKHSPIIGDIECTICKYRFKTKRNLQRHVLNHGKKYVCKLCPYNSSNITTVKQHQGSHKGITHKCNYCDEVFTVRTTYVSHMRIKHPSENICGLCGYSFYSKQGLLVHKNMVHKDILIKVEENKDEGLYCAECDVRFISTEAFKRHMVMSVKHTESTDTINGCRVCGAKFSGPEKLRLHHRKEHPEKQPKNYRVNKWPAKCEHCSEEMPSTRAYLKHFRLVHPEENYPLQKKCVCDICGKLFMCNALLVMHKRTHFGERPYKCSQCDTACFTGFDLRVHQQKHSDIRPFPCTVCTKAFKRKEALERHLKIHSGDNLYKCEICGVAFNKPCTRTLHVRTEHARAPAPARARRMRKPAGCV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -