Dcae024659.1
Basic Information
- Insect
- Diloba caeruleocephala
- Gene Symbol
- topi
- Assembly
- GCA_947459985.1
- Location
- OX381618.1:3516088-3533457[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0019 0.16 13.0 1.3 1 23 263 285 263 285 0.98 2 12 0.0039 0.32 12.1 1.1 2 20 293 311 292 314 0.92 3 12 0.7 57 5.0 0.3 1 23 318 340 318 340 0.94 4 12 9.5e-05 0.0078 17.1 0.8 1 23 345 368 345 368 0.98 5 12 0.0006 0.049 14.6 0.2 1 23 372 395 372 395 0.94 6 12 0.015 1.3 10.2 0.2 3 20 411 428 410 434 0.92 7 12 4.4e-05 0.0036 18.2 1.2 3 23 445 466 445 466 0.97 8 12 0.15 13 7.1 0.8 2 23 486 508 485 508 0.96 9 12 4.6e-06 0.00038 21.3 0.5 1 23 519 541 519 541 0.99 10 12 1e-06 8.3e-05 23.3 1.9 1 23 547 569 547 569 0.99 11 12 0.42 34 5.7 5.8 1 21 575 595 575 597 0.94 12 12 1.7e-05 0.0014 19.5 0.5 1 23 603 626 603 626 0.98
Sequence Information
- Coding Sequence
- ATGGAAGACATGAAAGTGTGCCGTATTTGTTTAAATATGGATGTGAAATTGCACGATCTCCGGTCATACCCTTTAGAATCGTACTTTGAGTCAATAATAGGAAATAATCCTCTGTACACCAACTTGCCACCATACGCTTGCTATGAGTGTGCAGCTCTTGTGAAAAAGTTTTATTTTTTTAGACAGAAGTGTCTTAGGGGTCAGGCTGTGCTCCATGGAATTACAGATCAGAATGGAAAGCTGATACCTGCAGATATAAAAGCAATTGACAGAAAGAGTCTGCACATAGCTTCATACCTCAAAGTCATCTCTATACCAGAAGTAAACATTATAGACTATCAGTACACAGACAAAATAGTGAAACAAGAATCAGTTATTGATGATGGCAAACCTAACTATAATGTAGCTTTTGAAGTAAAAGAAGAAGATAATGATTATGATAGCTTCCCATTACTGGACCACGGTCTATCAATATCTAGTGATGATGATGAGCCGCTATCACATCATAAGAAGAAGAAAAGACGAAAGGGAGGAAAGGATGTGGAGGAGTATTTGGCCTTAAATGAGGAAATGGAAGGTCTTGAATTACCGCAAGCCACAGATGACCTATCAGAACTGCCTTCTGAATTATCTCAGATAGTTGAAACACAGAAGAGAGCCAGGCCTAAGAACCCAAGGCGGATTGGAGACATCTGGCAATATGTCACTGTTATAACTCTGTCAATGGAAGAGCAAATAGAAGAGGTAAACAAACGCAAGGAGTCCTCCAACTACATCAACTCTCCGTATCAATGCAACCTATGCTTTAAAGGGTTCATCGACACAGGCGCCTGGAAACACCACGTCAGTAAACATTCTCCGAGTGCAGGTGACGTAGAATGTTCAGTCTGCAAGTTCCGGTTTAAAACTTTGCGCGCCCTCAAGAAACACACGCCCAGCCACGAAAAGAAGTATGCCTGCAAATCATGCCCATATATCTCTACTAACACAACACAAGCAAAGCAGCATCAAGGATGGCACAAAGGAGTTACGTTCAAGTGTAAATATTGTGATGAAATATTTTCTATATGGACTTCGTACATGAGCCACGTGCGGATCAAACACCCATCGGAGTTTATATGCGGAATATGTGGCTACTCGTTCATAAGCAAGTTGGGGCTCAACATGCACAAAACAATGATGCATAAGGATGTCTTGGAAAGCACTGACGAGAACAAAGAAGGACCGTACTGTGCAGAGTGCGACGTCAAGTTCATATCAATGGAAGCGTTCAAGCGACACATGGTGATGTCCGTCAAGCACACTGAGAGTACAGAACTTATCAACAAAGGCTGTCGTTCCTGCGGCGAAACATTCAAGACTTCTGAAGAGTTAAGGCTTCATCAACGTAAAGAACACACGCGGAAAAGACCCAAGAACTACGGCAAGAAACCGTCCAACATCGTATGGCCGACCAAATGTGAACATTGTTCAGAAGAAATCCCAAATGCGCGGGAGTACTGGACCCATTTCCGTCGCGAGCATCCTGATAAGAAATATCCCGTACAGAAAGACTACGTGTGTGACATATGTGGAAAAAGTTTCAGGGGCAATGCATTCCTAGTGTACCACAAACGTACACACTTTGAGGAGCGTGCATTCAAATGTTCCCAGTGCGGCAAGGCGTTCTTCAACCGCACTAACTTACAGGTGCATGAGAAAACGCACTCCGAAGACAGGCCATACCCTTGCAGCGTGTGCTGTAAAGGTTTTAAGTTCAAAGCAGCGCTCAATAGACACTTTAGATGTCACACAGGTCAAAAACCATACGAATGTGAGTTATGCGGCAAAGGCTTCTCGCAATCAAACAGCAGGAAGCTTCACGTACGTACGGTGCACCTGAAGCAACCCGCGCCCTACGTCAGTCGCACTCGGGTCGAGCGACGCACCAAACAGAGCCAGAAGGATCCATCTGCACAGCAGTTTATATACTGA
- Protein Sequence
- MEDMKVCRICLNMDVKLHDLRSYPLESYFESIIGNNPLYTNLPPYACYECAALVKKFYFFRQKCLRGQAVLHGITDQNGKLIPADIKAIDRKSLHIASYLKVISIPEVNIIDYQYTDKIVKQESVIDDGKPNYNVAFEVKEEDNDYDSFPLLDHGLSISSDDDEPLSHHKKKKRRKGGKDVEEYLALNEEMEGLELPQATDDLSELPSELSQIVETQKRARPKNPRRIGDIWQYVTVITLSMEEQIEEVNKRKESSNYINSPYQCNLCFKGFIDTGAWKHHVSKHSPSAGDVECSVCKFRFKTLRALKKHTPSHEKKYACKSCPYISTNTTQAKQHQGWHKGVTFKCKYCDEIFSIWTSYMSHVRIKHPSEFICGICGYSFISKLGLNMHKTMMHKDVLESTDENKEGPYCAECDVKFISMEAFKRHMVMSVKHTESTELINKGCRSCGETFKTSEELRLHQRKEHTRKRPKNYGKKPSNIVWPTKCEHCSEEIPNAREYWTHFRREHPDKKYPVQKDYVCDICGKSFRGNAFLVYHKRTHFEERAFKCSQCGKAFFNRTNLQVHEKTHSEDRPYPCSVCCKGFKFKAALNRHFRCHTGQKPYECELCGKGFSQSNSRKLHVRTVHLKQPAPYVSRTRVERRTKQSQKDPSAQQFIY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -