Dbru031836.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diarsia brunnea
Gene Symbol
-
Assembly
GCA_949774965.1
Location
OX459025.1:4764523-4766832[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.45 44 5.8 1.3 1 23 99 122 99 122 0.93
2 10 0.0067 0.65 11.6 0.4 2 23 149 171 148 171 0.94
3 10 0.015 1.4 10.5 3.0 2 23 194 215 193 215 0.97
4 10 0.012 1.1 10.8 0.0 1 23 219 241 219 241 0.96
5 10 0.0031 0.3 12.6 3.2 1 23 246 269 246 269 0.98
6 10 0.013 1.3 10.7 0.9 1 23 275 298 275 298 0.91
7 10 0.0099 0.95 11.1 1.6 2 23 306 328 305 328 0.96
8 10 0.00092 0.088 14.3 1.5 1 23 334 356 334 356 0.96
9 10 0.00019 0.018 16.5 0.2 1 23 362 384 362 384 0.99
10 10 4.8e-05 0.0046 18.3 5.3 1 23 390 413 390 413 0.98

Sequence Information

Coding Sequence
ATGTACTCAATGCGACATGGCGTTCTATTCGACGACAAAGTTGAAAAGTCATATGGTAAACCTCAAGCAGATACAGTCGCAATTAAAAAGGAGGCCTGCCAACCGCATACTACGAAAGGAAAAAATGCACCCCCGAAAATTGGTGCTGGACATCCTAGGGTAGCGGGATCAAACTGCAACAACCCTATAGCATCGAAATGGTTCAGTTATGAAATTTACAAACATAAGTcgaatattattgaaataatgCAGTGTTCCAACGCTACACCAATTAAAATGTGGGGAGATAAAGGTTACATGTGTTGTCACTGTGAAGATCAATACCCTGAAGCGGCAGATCTCAAGAAACACACCCTAGAAGAGCATGAGGACGTCTCCAAAACATGCTTCTTGAAAAACATGAGCATGTACCATTACTTAGTCAAATTAGACATCACCGATCTACATTGCAAGATCTGTAACAAAAGTATCGACACTGTTGAAGAACTTATGGAACACTTGCAGAATGAACACAAGAAATTAATATATACTGACATTAAAAACCATGTAATCCCTTTCAAGTTAAACACAAAACCTCTGGAATGTTTCATTTGTAAGAATGTTTTtcacaaattcaaattattaacCATACATATGAATAAACACTACAGGAACTATGTATGTGATATCTGCGATGCCGGTTTCGTCAACATTTCTGGAATAAGGCTTCATAAATCGATACACAAAATCGGAAATTACAGCTGCACAACTTGTTCTATGACTTTTGATACAAAAGTTAAGAGAAACCGACATGTTAAAACTAAGCATGCCAAAGAGATTCGCCACACATGTGGTTACTGcaaagaaagtttcaacgaTTATAGGAAGAAGGAAGCTCATCTGATTGCCGCTCACGGAATGACACAGCCGAAGTTAAAATGCCAAGCGTGCGACAAATTATTTGATCACCAAAAACGGTTAGCCGTTCACTTAAAGAGAGATCACTTAATGGAAAGGCCACATGCTTGCACAGTGTGTGAGAAGAAGTTCTTCGCTTTGGGCGAGCTTAGAAATCATATGACGAAGCATACAGGAGAGAGACCTTATAAGTGCGAAGTTTGTTTAAAGGCGTATGGATTGGCGAAGACATTGAAGGAGCATATGAGGATTCATAATGATGATCGGCGTTTCAAATGCGATCATTGTGGACAGGCTTTCGTCCAGAAGTGTAGCTGGAGGAGTCATATGAAAAGTAAGCATGGGCAGAAAgtttaa
Protein Sequence
MYSMRHGVLFDDKVEKSYGKPQADTVAIKKEACQPHTTKGKNAPPKIGAGHPRVAGSNCNNPIASKWFSYEIYKHKSNIIEIMQCSNATPIKMWGDKGYMCCHCEDQYPEAADLKKHTLEEHEDVSKTCFLKNMSMYHYLVKLDITDLHCKICNKSIDTVEELMEHLQNEHKKLIYTDIKNHVIPFKLNTKPLECFICKNVFHKFKLLTIHMNKHYRNYVCDICDAGFVNISGIRLHKSIHKIGNYSCTTCSMTFDTKVKRNRHVKTKHAKEIRHTCGYCKESFNDYRKKEAHLIAAHGMTQPKLKCQACDKLFDHQKRLAVHLKRDHLMERPHACTVCEKKFFALGELRNHMTKHTGERPYKCEVCLKAYGLAKTLKEHMRIHNDDRRFKCDHCGQAFVQKCSWRSHMKSKHGQKV