Dbru027120.1
Basic Information
- Insect
- Diarsia brunnea
- Gene Symbol
- -
- Assembly
- GCA_949774965.1
- Location
- OX459018.1:4257018-4264294[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 5.2 5e+02 2.5 0.1 2 17 56 71 55 72 0.85 2 10 9.2e-05 0.0088 17.5 4.1 1 20 202 221 202 224 0.94 3 10 0.0002 0.019 16.4 0.6 1 23 230 252 230 252 0.96 4 10 1.2e-05 0.0011 20.2 2.0 1 23 258 280 258 280 0.98 5 10 9.2e-07 8.8e-05 23.7 0.8 1 23 286 308 286 308 0.98 6 10 1.6e-05 0.0016 19.8 0.1 1 23 314 336 314 336 0.96 7 10 1.2e-06 0.00012 23.4 1.3 1 23 342 364 342 364 0.98 8 10 0.00012 0.012 17.0 2.8 1 23 370 392 370 392 0.98 9 10 0.00037 0.036 15.5 1.6 5 23 401 419 399 419 0.94 10 10 6.3e-06 0.00061 21.1 5.5 1 23 425 448 425 448 0.97
Sequence Information
- Coding Sequence
- ATGGCATTAGACTTTACAAAAGTTTGTCGAATATGtctcgaaaaaaataaaataacatacgaTATTTACACAAGTTACTATGCGAAAAAGAATACTTTATATAGTGATATGTTAATAAACTACACTAAGTTGAAGCCACAAATAGGAGATGGTCTACCTCGTTTAATTTGTAAAGAATGTAGCCGACAGCTTAGACGTACATACGACTTTAATATACAATGCGAAGACAGTgatgaaattttaaaatattggttGGAAAACTCGCCTAAGGTGGACAATACAAAAAATGGTTGTTCTGACGACTTAGTCAAAGATGAACTGAATTTTGAAGATTTAAAATTAGAGAATAGCCATGAAGCGAACGGGGAACTACTGACGACGCAATATGATAATAATCAAGAAGATATCAAGGATATTAAACTAGAACTAAATGATGATGGTAATGATAGTTGCTGGGATGCTGATGATGACAACATGTTGTTAGgagaaatcaaaaataaaaaatcagAAAATACAGAGGAAAAGCCCAAAAAGAAAAGAGGTAGAAAGAAAAAAGTGTACCTAGAGGGCGAACTCCCGCACGTACCGGAAAGCAAGCTTCCTCATCAGTGCGACATCTGCGGCAAGTTCCTTAGCACGAAGAGCAACTTGAAGGCTCACAAATTGTGTCATACAGATCTCAGGCCGTATCTCTGTCCAGAATGTCCTGCTACTTTTAGAGGTCACAGTGCATTATTTCAACATAAGAAAGTACATACTGGTGAGACCCCGTACCACTGCACGTACTGTCCCAAACAGTTTGGCAGAAGAACTGGACTCGTCAACCATATACGTATGCACAAAGGAGAAAAACTGTACAGCTGTGAGATTTGCTTCAAAACGTTTGTACAGAGCGCTCAGCTGTCTATACATATGAAGCGACATAAAGGAGATAAGCCGTATTTATGTCAAGTTTGTGGAAAAGGTTTCCCAATAAAAGCAGAGTTGAAGGTTCACCAGCGAATCCACAACGGTGAAAAGCCGTACTCTTGTCACCTCTGCACCAAGACCTTCGCAACTTCAGGAAACTTGTCTATACATGTTAGGATACATAATAAGGAAGTTAGATACAACTGCAAAGAATGTCAACGCGGTTTTGTAACCTGCAGTGCTTACAACGTCCACCTGAAAAGACATAAAGGACAACGTGACTATCACTGCGAGTGTGGCAAGACTTTCTACACGTCTTCCGCGCTAAAACAACACAGGGTAGTCCACACAGGAGAAAAGAAGTACCAATGCAAAATATGCGACAGAAAGTTCACACAAACTAGTCATTTGAGTCGACATTTTAAAAGAGATCACGCTAAACCGAACGCACCTGTACCTTCCTCTGATCATTATAAAGTTGTGTTGCCagagaataaaaatgtttttaatctgTTAGATAATGCGATACAGAAGATTGGACAGAATATGAGTACGGATGTTAAGTGCGAAGGGTCGTAG
- Protein Sequence
- MALDFTKVCRICLEKNKITYDIYTSYYAKKNTLYSDMLINYTKLKPQIGDGLPRLICKECSRQLRRTYDFNIQCEDSDEILKYWLENSPKVDNTKNGCSDDLVKDELNFEDLKLENSHEANGELLTTQYDNNQEDIKDIKLELNDDGNDSCWDADDDNMLLGEIKNKKSENTEEKPKKKRGRKKKVYLEGELPHVPESKLPHQCDICGKFLSTKSNLKAHKLCHTDLRPYLCPECPATFRGHSALFQHKKVHTGETPYHCTYCPKQFGRRTGLVNHIRMHKGEKLYSCEICFKTFVQSAQLSIHMKRHKGDKPYLCQVCGKGFPIKAELKVHQRIHNGEKPYSCHLCTKTFATSGNLSIHVRIHNKEVRYNCKECQRGFVTCSAYNVHLKRHKGQRDYHCECGKTFYTSSALKQHRVVHTGEKKYQCKICDRKFTQTSHLSRHFKRDHAKPNAPVPSSDHYKVVLPENKNVFNLLDNAIQKIGQNMSTDVKCEGS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00746043;
- 90% Identity
- iTF_01064902;
- 80% Identity
- -