Basic Information

Gene Symbol
Prdm15
Assembly
GCA_034092305.1
Location
JASJET010000043.1:8510221-8523641[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.072 10 8.5 0.4 1 20 247 266 247 271 0.91
2 12 0.00053 0.076 15.2 3.5 1 23 277 299 277 299 0.99
3 12 4.7e-07 6.6e-05 24.8 3.0 2 23 306 327 305 327 0.97
4 12 0.00067 0.095 14.8 1.8 1 23 333 355 333 355 0.98
5 12 0.0032 0.45 12.7 1.7 3 23 362 382 361 382 0.98
6 12 0.00024 0.034 16.3 0.4 1 23 399 421 399 421 0.98
7 12 9e-05 0.013 17.6 0.6 1 23 426 449 426 449 0.95
8 12 3e-06 0.00042 22.2 1.8 1 23 454 476 454 476 0.98
9 12 1.8e-05 0.0026 19.8 0.5 1 23 482 504 482 504 0.99
10 12 0.0021 0.3 13.3 2.3 1 23 510 532 510 532 0.99
11 12 3.7e-05 0.0053 18.8 0.4 1 23 538 560 538 560 0.96
12 12 1.7e-05 0.0025 19.8 1.8 1 23 566 588 566 588 0.97

Sequence Information

Coding Sequence
atgaATATGTCTGGTAATTACCTTGTAGCAGTACCAACAAGCGAAGCGAACAGCCAAGCAAATatgaataaatatgaaatattacCCTCTAGTTCTTTCCACAATATTTGTCGGACATGTTTAATGCAtgatgaattgtttttaattcatgAAGTAAACAGAGAAGACATAAGCTTAATAGAAATTATACAGGATTGGACACCCCTACAGtttaCAAATGATGATCAATTGCCACACAATATGTGTAAAGATTGCATAAAATATATGTATCAGACATACCGTTTTATGTCAAAATGTAAAAGTtcagaaaaagttttgaaaaatattttaataaaagaatcaataaaaattgaaGTGGACGACTCAACAATAGAATTAACAACAGTGAGTGAACAAATCGAAAATACAAATATTAAGTCTGAGAATGATATGGATAGTTTAGCTGGTAATAATGATCAGCGTATGGAggaaaattttttagttaaaactaATGATAATTACTCTGATATCAATTATCCAACTGAAGTTAAAAGTGAAATCTCTAATAGTGAAGAACAAACTGAGGATATAAATCttgattataatatattaaataagataCCAAGTACTAAGAATCAAATAAGTAAAATTAGGGTAAAGAATATAGTTAAATTGCGACAGATGGCGAAAGCACAATTAGTTGATTATAGTGATTTACCAAAAAGTCATAAAAGGATTGTGTTTAGAaaagGGCCACCTTATATTTGTGTCACTTGTGACTCATCATATCAAACCCAGGAAGAACTGAAAGAACACAAAATcgaaacaaaacataaaaaatctcTTAGGTTTACATGCCCACattgtgaaagaaaatatggcgattattattattataaagagcATGTGAGAACCCATACAGGGGAAAAACCAAATAAATGCACTATTTGTGGTAAATGTTTTAATTCTAAAGCTAACCTAAAAAGGCATGTGGTTACGCATATGGATGTTAAACCATATAGTTGCCGATTTTGTAACAAAGGATTCGCTAGAATACAATATCTTAGGGACCACGAAAGAAAACATACAGGGGAAAAGCTGCTTTGTCCGTTTTGTGGAAAAGGCTTCAACTcgcattcaattttatttaatcatGAAAAGACTCACAAGAGACCATCTGGAAGCGTTGAAGATCCATTGGCAAAAGATTGGTTATTTCagtgtcatatatgtgataaagtTCTAGGGACTGATCAGACTTTAAAAGCTCACATTTTACTACATGGATCTCGAGACTTTACCTGTGAAATCTGTGGAAAAACTTACATTAGTGAAAATAGGTTACAAGATCATATTAAATTTACCCATCAAGaaaacaaatattCGTGTCACTTATGTGATAAAGAATATAAGCAAAAGAGTGGATTGGTAGTTCATTTGAGATCACATTCTGGCCAAAATAATTATCGATGTGAAACATGCGGCAAACAGTTTGCATTGAAAGGTTCATTGGTTCAACATAAAAGGGTGCATACAgGTGACACAACATATCAGTGCAAAGAATGCCTTCAAATTTGTATTAATAAGCGCCGTCTGGAAATTCACCTACGTACTCACACAGGAGAAAAACCGTTTGCTTGCGAGTTTTGTGGGAAACTTTTCGcacaaaaatcaaatatgcaagCGCACTCAAAAATCCACGCCGAAGAAAAAACTCATAGATGTAAATTGTGCGAAAAAGCCTTTTATGATGCTCGAGGATTGAAAAAACACATGAGTATTCATGAAAAGAATGGTGATGTAGAAAATGTGTAA
Protein Sequence
MNMSGNYLVAVPTSEANSQANMNKYEILPSSSFHNICRTCLMHDELFLIHEVNREDISLIEIIQDWTPLQFTNDDQLPHNMCKDCIKYMYQTYRFMSKCKSSEKVLKNILIKESIKIEVDDSTIELTTVSEQIENTNIKSENDMDSLAGNNDQRMEENFLVKTNDNYSDINYPTEVKSEISNSEEQTEDINLDYNILNKIPSTKNQISKIRVKNIVKLRQMAKAQLVDYSDLPKSHKRIVFRKGPPYICVTCDSSYQTQEELKEHKIETKHKKSLRFTCPHCERKYGDYYYYKEHVRTHTGEKPNKCTICGKCFNSKANLKRHVVTHMDVKPYSCRFCNKGFARIQYLRDHERKHTGEKLLCPFCGKGFNSHSILFNHEKTHKRPSGSVEDPLAKDWLFQCHICDKVLGTDQTLKAHILLHGSRDFTCEICGKTYISENRLQDHIKFTHQENKYSCHLCDKEYKQKSGLVVHLRSHSGQNNYRCETCGKQFALKGSLVQHKRVHTGDTTYQCKECLQICINKRRLEIHLRTHTGEKPFACEFCGKLFAQKSNMQAHSKIHAEEKTHRCKLCEKAFYDARGLKKHMSIHEKNGDVENV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01239433;
90% Identity
-
80% Identity
-