Basic Information

Gene Symbol
-
Assembly
GCA_034092305.1
Location
JASJET010000054.1:16529454-16571280[-]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 8.1e-11 8e-08 34.6 1.9 1 71 671 732 671 744 0.78
2 7 0.00023 0.23 13.9 0.2 1 61 811 868 811 892 0.74
3 7 1.4e-11 1.4e-08 37.0 0.3 1 84 1053 1134 1053 1136 0.78
4 7 1.2e-09 1.1e-06 30.9 0.2 1 69 1197 1261 1197 1278 0.74
5 7 6.2e-11 6.1e-08 35.0 0.5 1 62 1304 1363 1304 1384 0.80
6 7 1.7e-05 0.017 17.6 0.9 1 40 1407 1444 1407 1457 0.89
7 7 1.7e-08 1.7e-05 27.2 0.2 1 61 1480 1535 1480 1565 0.75

Sequence Information

Coding Sequence
ATGAACAAAATATGCAGACTGTGCCTAAAAGAAACGACTATAACGTTTAGTATCCATTATACAGATATTAATGGTATTTCAATTTCAAGTTTTGTAAAAGCTTTAATTCCAGAATtggtagATGATTCTGGAAAACCAATAATACTaaaccaaaatacaaatataagtgATCTTACTGAAAATGCTAGTGACACGGAAGACGATGTATTTTCAGAGGAACCTAGTACCAGTACTCAATATATACAGaaagataatatttatattttacaaaaagaaaagaCCACTTCTGAGTTGGATTCTCAGAAAAAAGACGGTCATGCTGCAGTGGATGATACCGTAATCGTGACGAAAATACCATTTAATACCGTAAAGATTCAATCAAATGAACGTATGGCTAAAAGTAAAACGGTAGAGTCTGAAATACCTGTTAATATTATAGAAAAGGTAGGTCCCATACGAACCTATATAAAGAAACCAAAAAACGTAGAGGAAGAGGCTGACAACACTAACTCACAAGAAACCTCCACATTGAAAGTGGTTAATGCTAAAAAACGGATTCATTTGGAACCATATGATGTAAATGACAAAGAAACAGCCTGTCTCATTGAGGAGTTACAAAAGACTGAGAACTTAGCGAAACTAGGGATCACTGCTAATGCTACGGATGAAGTTTACATTCTTAGAAAATTCCTTAATCCATCTGATAATGTAGTAAATTTTGCCCTGGTACCGAAAAGGATTTCCCAGAATGatagaaataaacaaatagaCGTATTGTTGAATGTCTTTAACCAAGGAAAAACATCGGTTAAAGCGGCTGGCAAATCAGGGGAAAAATCTGATCATAATGAGGACTTACCAAaagtaataaacaataaaatgttaAACCAAAATGCTTCGGGTATAACGGAAAATGTTGAATTTGATTCCAACTATACCCAAAAAGGGTTAACGTgttgtaaagtaaaaaaatattatagaaagttACCGCCAGGGAGTCATTCCATCAAATTTTCTAAAGAAGGTAATAAAGATAATAGCAGTATATCTGAAAATACTGGAAATTTGGACCCATCAGCTCAGAAAAGTGATAAAGAATCGTTAGATAGTATAACACTTTCTCTTGACTCTAAGAAGGCAGATGAAGCAATAAAGTCAGCAGATCCTACATCCGAATATAAATCTCGGTCAAAACCAATGCCAGTTATTCGAGTGCGTCCAGTGTCAACCCTCCAAAAAGTTCGTACCCTAAATCATGAActttggcctcaaaaaccaggATTTCTTAAGTTAGATTTTGAGCCAATTAAAAATCTAAATGAAACGAGCCCCAAAGTAATAAACTCAGAGTCAGCTTCCTCCGAACTTGTGAACTCCAATAAAACCCCAACGGCACGAATATTAAAAACTTATCTCAAAAGAGGCACTATTAAAACTAAAGGCAACGCATTCAAACCTATAGTCTTAAGAACTATAAACCCAGCAACGTTAAAAGCATCCGGGACAAGGCACAGGTTAATAAAACCAAAACCGGCTCCTCCTGCCACCACCGACAGTTCTCGGGAAGATAGTGTTAGTGAAGACGTCATTGATATTAAAGAAGAACCGTTGGATTATGCGGAAAGTAACACGTTGGATACGGCGAACTTTGGTTCAAATGGTAATAATCCTGTAACTTCTGCTGAATCTGATGGTGAGAAGACGAGAAGCGCTAGCGAAACGTCGTTTATGGACACATTGAGTAATCAAAATGAAATACTACAATCAATTGTAGCTAATATACCAGAACTGGGGGATGATCAGTACGACGAGCCCGAGTACATTCACATCAACAATGTCTCTTATTCAGACTTGGCAAAACTAGTAGATGAAAGCAAGAAACATCGAGACGAACTAGGGAAGGCACCGACAGAAAATCCCGACCCGGTGAATATAAAAACGGAAGTAAAAGTGCAAAAACCAGAATCGAGTGTCGACGGTAGTCCAGCGAGTTATTCCGTGCCTAGATACTGTTTCGTGCCAGGTTGTAAAAATAACTCGAAATCGTGTCCCGAAAAAATGTTTGTAAGGGTGCCGACAGACAAGGAAGAGCAAAGAGCTTGGTTCGATGTAGTTGGACGACGATTTTTTCCACTCTCCTCCATATCGTACTTTTGCTGTGAAGACCATTTTAATgttaaagaAGATATGGAAAATTATTCGGAATATAAAAAATTGGGTGGTTTCCGAAATCCCGAATTGACATTTAGTAAAAATAGCTTAGCGACAATATCTGAACTTCTAGATAGTTCTTTAATATTGAAAGAAACACCGGCGCAATCTATTGGTGAAACAAGCGAACCTACCCAACAAATACAACCACATATTGAAGTAAGCGAAGCCGGTACCAACGAGGATCAGACACAAGTAGCGTCTAACCGTGTTAGGTGTTGTTTTGTACCAGGTTGTAAGAGTAACTCGAGAACATGCCCGACTAAACGATTTACAGATCTACCTTCGGACAAGGAAATGCAGAAAGAATTATTTCGGGCATTTAGGATGCGGTATTATCCTATTCAAGATTACCAACTTTTTTCTTACTGCGAGGATCATTCTGAAATAAACAAAGATATCGAAAATTATCTGAAATATAGAATATTCGATGGTACAATAATGAAAAAAGGCGTTATGCCTCATAAACTTATTCGCGCTGCAAATCCAGGTTCGATATTTAATGATGATTTAGTTTTTGAAACTAAATCACCAAATGACAACGTCGTATCAATAGAACCATCAGTTGATTCTATCGATGAAAcgcgattaaaaataaataaaccttcTGGAGATTTAGAACCACCTTACAAAATTGATAAAGATGAACCGAAAACATCAGATGATGAGCCTATTGGTAAAACAAATGAATTTACCAAAGGGGTACAACCATATGCCGAAATAAGTGATGTTTGCAAAGATTCAGAAATATCTAATAAAGTTGAGCAAGAAGAACTGAAAATATcagatgatgataatgatgatgcgTTATTAGAATCTACAATTTATCATGAAGCTGAATCGATTGCAGAGAAACATGACAATAAAATACAAACATTCACTGAAATCAGTGAAACTTGTCCTAAAGAAAAAAATGCAACAGCAGCTTCTAGCCATATTAAGTACTGTTTTGTACCAGGTTGTCAGAGTAACTCAGAAAAATATCCCAATAAAATATTTGCAAGTCTGCCTACGGACAAAGAAACGCTAAAACGGTGGTTTGAAACAGTTGAACGACAGGATATTCCTTTTCAAGACTACCACCTTTATTTTTGCTGccaagatcattttgatATCGAAACAGATATGGAAAAGTATACAGAATATAAAAAGTTTGGCggtactgcaataataaaaacaGGAGTTATTCCTCATAAGCGTTTGTGTTTGGAAGAACTCGATACGGATAATTTGATTTCGGAACCTGAAGGGTCAGATGATGATGTGGTGATAATAGAACCTATTGGTGAAACACAATTAAATATCAACGAACCACCTTTTAAAGTTGGTGACAAAGTATCGCGTACTAAAAACAGTCGAATCACCTCCGTTAAGAAGTGTTTTGTTCGATCCTGCAACAACACTTCCAAATTAAATCCaaccaaaatatttgtaaatgtaCCGGCCAACAAGAAAGTACGGAAACACTGGTTTGATGTAGTTGGGCGATCTTATGCTCTTTCTAAAGGGGATTACAATTgctgtgaagatcattttgatTTGGAGaaagatatggaaaattatatgagCTATACATCATTTGGTGGCACATTAATAGTTAAAGAGGGAGTTATTCCTCACAAACTTCTTAATCCCGGAGAAGAAAATCTAGATCAAACAGAgaatcaatttaaattaattcgTACACGTTTTAAGTACTGCTTTGTACCAGGCTGCAAAAGTAATTCGTCATTGTATTCATCTAAAATATTCGTAAATGTGCCCATGGACACGGAAATCCAGAAACGATGGTTTAATGCAGTTTCACGACGACCTGCTAATGTTAAAACGAAATATGTTtgttgtgaagatcattttgatACGGAGctattaaaacaatataaaaactttggtgaTATTATACTGAGGAACGAGTGGTTCCTCCCTCGTGTTGCAAAACCTGAATCCTCAACAAACATCGAAGCGATTAAAAAAAACGCACCACAGCCCACATCCACCACCAAGTTCTGTTTCGTACCAAACTGTACAAATAACTCTGAAACAGATAACTCTCAATTATTTATGAAAGTACCCGAAGAATCTGAAGAGCAACAGTTTTGGTTTCAAGCAGTTGGACGGAAATTTTCAGGTGTTTTAGCGAACCTATGGTGCTGCGACGACTGTGGTAAAAAGTTGAGGGAAAAAGGAATTTTCCGTCACAAAGCCTGTTATGCGCGCCGTAAGCACTGTTTCGTTTCAAATTGTAAGAATAATTCGATATCAaatcattcaaaaatatttattaaagtgCCCCCTGAAGCTGAAGAGCAGAAACGGTGGTTTAAGGCAGCCGGAAAGCCCTATTCGGGTGTTACATCAAACCTATGGTTCTGCGAGGACcattttaataCCCTAAAAGATATCGACGCTTATTTGAATCGTGTTCCTTCCGATGGTTCAATACTTGAGAGAAAAGAAGTTCTCCCTAGTAAATCAGTTCCAGATTCAGAGCCACCAAgtaaaaaacttaaaagaaatAGCATGCAGTTAGATGATTTAAGGATAGGTATCGTCGATACGGAAAAGATTAAAGTGGAACCAAACTTGTAA
Protein Sequence
MNKICRLCLKETTITFSIHYTDINGISISSFVKALIPELVDDSGKPIILNQNTNISDLTENASDTEDDVFSEEPSTSTQYIQKDNIYILQKEKTTSELDSQKKDGHAAVDDTVIVTKIPFNTVKIQSNERMAKSKTVESEIPVNIIEKVGPIRTYIKKPKNVEEEADNTNSQETSTLKVVNAKKRIHLEPYDVNDKETACLIEELQKTENLAKLGITANATDEVYILRKFLNPSDNVVNFALVPKRISQNDRNKQIDVLLNVFNQGKTSVKAAGKSGEKSDHNEDLPKVINNKMLNQNASGITENVEFDSNYTQKGLTCCKVKKYYRKLPPGSHSIKFSKEGNKDNSSISENTGNLDPSAQKSDKESLDSITLSLDSKKADEAIKSADPTSEYKSRSKPMPVIRVRPVSTLQKVRTLNHELWPQKPGFLKLDFEPIKNLNETSPKVINSESASSELVNSNKTPTARILKTYLKRGTIKTKGNAFKPIVLRTINPATLKASGTRHRLIKPKPAPPATTDSSREDSVSEDVIDIKEEPLDYAESNTLDTANFGSNGNNPVTSAESDGEKTRSASETSFMDTLSNQNEILQSIVANIPELGDDQYDEPEYIHINNVSYSDLAKLVDESKKHRDELGKAPTENPDPVNIKTEVKVQKPESSVDGSPASYSVPRYCFVPGCKNNSKSCPEKMFVRVPTDKEEQRAWFDVVGRRFFPLSSISYFCCEDHFNVKEDMENYSEYKKLGGFRNPELTFSKNSLATISELLDSSLILKETPAQSIGETSEPTQQIQPHIEVSEAGTNEDQTQVASNRVRCCFVPGCKSNSRTCPTKRFTDLPSDKEMQKELFRAFRMRYYPIQDYQLFSYCEDHSEINKDIENYLKYRIFDGTIMKKGVMPHKLIRAANPGSIFNDDLVFETKSPNDNVVSIEPSVDSIDETRLKINKPSGDLEPPYKIDKDEPKTSDDEPIGKTNEFTKGVQPYAEISDVCKDSEISNKVEQEELKISDDDNDDALLESTIYHEAESIAEKHDNKIQTFTEISETCPKEKNATAASSHIKYCFVPGCQSNSEKYPNKIFASLPTDKETLKRWFETVERQDIPFQDYHLYFCCQDHFDIETDMEKYTEYKKFGGTAIIKTGVIPHKRLCLEELDTDNLISEPEGSDDDVVIIEPIGETQLNINEPPFKVGDKVSRTKNSRITSVKKCFVRSCNNTSKLNPTKIFVNVPANKKVRKHWFDVVGRSYALSKGDYNCCEDHFDLEKDMENYMSYTSFGGTLIVKEGVIPHKLLNPGEENLDQTENQFKLIRTRFKYCFVPGCKSNSSLYSSKIFVNVPMDTEIQKRWFNAVSRRPANVKTKYVCCEDHFDTELLKQYKNFGDIILRNEWFLPRVAKPESSTNIEAIKKNAPQPTSTTKFCFVPNCTNNSETDNSQLFMKVPEESEEQQFWFQAVGRKFSGVLANLWCCDDCGKKLREKGIFRHKACYARRKHCFVSNCKNNSISNHSKIFIKVPPEAEEQKRWFKAAGKPYSGVTSNLWFCEDHFNTLKDIDAYLNRVPSDGSILERKEVLPSKSVPDSEPPSKKLKRNSMQLDDLRIGIVDTEKIKVEPNL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-