Basic Information

Insect: Diaphorina citri
Gene Symbol: MECOM
Assembly: GCA_000475195.1
Location: CP125333.1:51426434-51440562[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.85 75 5.5 0.0 2 23 460 482 459 482 0.95

2 8 1.3e-08 1.2e-06 30.0 1.4 1 23 516 538 516 539 0.96

3 8 1.9e-05 0.0017 20.1 2.5 1 23 545 567 545 567 0.95

4 8 8e-05 0.0071 18.1 7.0 1 23 573 595 573 595 0.99

5 8 0.0038 0.33 12.9 0.9 2 21 603 622 602 623 0.95

6 8 6.2e-09 5.5e-07 31.1 0.6 1 23 942 964 942 964 0.98

7 8 1.1e-06 9.4e-05 24.1 1.7 1 23 970 993 970 993 0.97

8 8 8.7e-06 0.00077 21.2 3.4 1 23 999 1021 999 1021 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.85	75	5.5	0.0	2	23	460	482	459	482	0.95
2	8	1.3e-08	1.2e-06	30.0	1.4	1	23	516	538	516	539	0.96
3	8	1.9e-05	0.0017	20.1	2.5	1	23	545	567	545	567	0.95
4	8	8e-05	0.0071	18.1	7.0	1	23	573	595	573	595	0.99
5	8	0.0038	0.33	12.9	0.9	2	21	603	622	602	623	0.95
6	8	6.2e-09	5.5e-07	31.1	0.6	1	23	942	964	942	964	0.98
7	8	1.1e-06	9.4e-05	24.1	1.7	1	23	970	993	970	993	0.97
8	8	8.7e-06	0.00077	21.2	3.4	1	23	999	1021	999	1021	0.99

Sequence Information

Coding Sequence: ATGCCTCGCAACTACAAGACTCCAGCAGGCAGTGTTCAGTACAAAAAACAAGATCctggtttgatagagaaagcAGTTGAGTATCAGAAGGAAACAGGTAAGCCATTTAGACAAGTGGCACAAAAGTTTGGGATAAACTATTCTGTTTTATACAgacacataaaaaagaaaaatgtgcgGAAAATTGGAGGGCAAACTGTTCTAACCAGTGCTGAAGAATCACTTATTGCCACTAACCTAGCCAAATGTGCAGAATGGGGCTATCCATTAGATCTGTTTGATCTCAGACTAATTGTTAAATCATATTTGGACCGTGGTGGTCAAGTGGTAAAAAGATTCAAAAACAATATGCCAGGTAGAGATTTTGCACTAAGTTTCATGAAGAGACATGAGAAGGATCTGGCAAGTCGCCTTTGTCAAAATATCAAAAGGGCAAGAGCATCTGTATCCCCAGAAGTTATAGATGAATATTTTCAGAATTTAAGACCAACTTTGGAAGGGGTGCCACACTCAAACATCATAAATTATGATGAAACCAATCTTTCAGACGATCCTGGGAAGTCGAGATTAATTTTCAAACGTGGATGTAAATATCCTGAGAGAATTATGAACAATAGTAAGTCCAGTACTTCAATTATGTTTGCTGCTTCTGCAGATGGAACTGTTCTACCACCCTACACTGTTTACAAAAGTGTTCATCTGTATCAGAGCTGGACACAAGGAGGCCCACCAAAGGCTCGTTATAATAGAACAAAGTCAGGATGGTTTGATTCCATTTGTTTTGATGATTGGATTGAAGAGCTTGTGATACCTCATTCAAGCAATGTTAAAGCTGGATTCAAAAAAGCAGGTATTGTTCCAATTGACCCCAACCAAGTCCTGAATAGGCTTCCTAACAATGTAACAACAACTGATCAAGATAATTTGGAGACCACATTAAACATGAATAATTCATTTGAAGAGCTTTTGAAACAAATGAGATATAATGATAACAACTCATCAACCAGAAAGAGAGCAAACAACAAATGCAAAGTTCAAGCTGGGAAAAGTGTTTCCCCTGAGGACCTGTCTCCTGAAAGTGAAATGAACCCTGATGATCCAGAGCCACTTTCTGAGTCTCCTGAGCCACTTCCTGAGTCTCCTGAGCCACTTCCTGTAAATCCATCTAATGAACTTGGGTTTATTAGCTCAGATGAAATAACTCCAGTAAATTGTCAGGCTGAAGTCCAAATTGATGACTGGGTGCTAGTTTACTTTGACCAAGAATGTTCTCACAAAACTAAGAAAAGGGGGTTCATTTGCCAGGTTATAGTATCTCAACACTCAGGCACAGTAGAAGAGGACAGAGAAGATGAGTTAGACGAGGATGACGAGATCCGATGCGTTGTCTGTGCTTCTGTGTTCCAGGATATTTACCAATTGGAGGACCATCTAATCACCGGCCATCGCTACCCACCCGATCAGTACCGCTGTGAGTCTTGCTCTCAAACTTTCTGCTGGAGACCCCATCTCAACTTCCATCAAGCTCAGGTCCACGGACGAAAGTTCCCCTGTGAGAATTGCACCAAGgTATTCTCTGATCCCAGCAATTTGCAACGACATATCCGCACCCATCACGTCGGGGCGCGACAGCATGCTTGTCAGGAGTGCGGCAAAACCTTCGCCACATCGTCCGGTCTGAAGCAGCACACTCACATTCACTCGAGCGTCAAACCGTTCCGCTGTGAAGTCTGCCACAAGgcCTACACCCAGTTCTCAAATTTGTGTCGTCATAAACGAATGCATGCAAACTGTCGGATGCAGATCAAATGTGTCAAGTGTGACCAATCCTTCAGTACTGTAACGTCGCTGTCCAAACATAAGAGATTCTGTGACTCGACCACACCAGGCACTACGCCATCAGGGCAGAACTCTCTATCAGCAATGTCTCACCAAACCCCTGGCATTCCTAATCCTTACCTGATGTACCCCCGGCCCGGTGGTACTTTACCATTCTACCCACCATCCCTGATGCCACCTTACCCAGGACTATTTCAACCCAACCAGACACCAACACCTCATCATCCATTTCTTTCAAATCCATTATTGTTCAACCAATCCATGAAATCCAATGAAGAACTGGACAGAGCGAAGATAAATATCAACCTCAGTGTTGAAGCATATTATAGGTTTCAACTGCAGAAGAATGTTCAACAGtctgaggaaaaaaggaaaaattctccttctcctcgtaaATCAGATGTACCGAAAACGTCTGGTGGAAAGTTATTCGAGTTTTCCGAAAGTAAAGATTCGCCACCCACAGCAGAAGAAGCAAACTCAAATCAGAGACCATCACCTGCCCGGCCTACCATCAGTGCAAGCAATGCTGTCACTTATCCTGATCCGAGGGAGCAACTGGAAGTTGTCACCACAGATGTCAAGAGTGATGTGAATCAGAAACCACGAGATAAACTTACCAATTTCTCCATAGATAAACTTAGTGGGAAAATGGATTCACAAAAAGATGAAGATGCCAGTGAGGAAAGTAAACCCAAAAAGGCAAAATACTGTGATCAACCTTTAGACTTGAGCATAGCATCAAAATCGTCTATTGATTCAGACAAGCAAGACACAAATGACACTTTTGTAAAGACACCGGCTACGTCCCCGGACATAGGACTTATGAACGGTATCAACAATAGTTTAGGTGTAAACAGAACTCCTTATGAACATCTTTTGCGTTCACAGATATCTCCTTATGCAAACAAGCCATTTCAAGAAATCCTAACCTCTCAAAATAACGCAGTAAATGGAAGTTCTAGTAAAACGACAAAAGACAGATATGCATGTAAATACTGCGGTAAAGTGTTCCCACGTTCTGCAAATCTTACTCGGCATTTGCGGACACACACAGGGGAGCAACCCTACAAGTGCAAGTATTGCGAAAGATCTTTCAGTATCTCATCCAACTTGCAACGGCATGTAAGAAATATCCACAACAAAGAGAAACCGTTCAAGTGTCCTTTGTGTGATCGATGTTTCGGTCAGCAAACGAATTTGGATCGACATCTGAAGAAGCATGAAGCGGATGATGGCAGTGGTCTTGTATCCATGGCAGATAGTCCTGAGAGTAGCaatgagaatgaaagagaagatgCTTACTTTGATGAAATCAGGAGTTTCATGGGAAAAGTCACATACTCAGGGGATGTGGCTTACAACCAGGAGAATTTGTATACGGGTACtaaccctccctctcctctcatTGATGTcaaggatgatgatgataatgagtCTGAATTTCTCTCTGATGAAACTGAAGACACATTTATACCTCAGGATTTCAGGAAATCTCCATCAGAGATAGAGAATGGATCTCCTATTTCATATAGTCTGAAAACCAAAGGAGATCAGGAAATTATCAACAACAATACCTCAAGTGCTGCTGATGCCATTACATTACACGCATAA
Protein Sequence: MPRNYKTPAGSVQYKKQDPGLIEKAVEYQKETGKPFRQVAQKFGINYSVLYRHIKKKNVRKIGGQTVLTSAEESLIATNLAKCAEWGYPLDLFDLRLIVKSYLDRGGQVVKRFKNNMPGRDFALSFMKRHEKDLASRLCQNIKRARASVSPEVIDEYFQNLRPTLEGVPHSNIINYDETNLSDDPGKSRLIFKRGCKYPERIMNNSKSSTSIMFAASADGTVLPPYTVYKSVHLYQSWTQGGPPKARYNRTKSGWFDSICFDDWIEELVIPHSSNVKAGFKKAGIVPIDPNQVLNRLPNNVTTTDQDNLETTLNMNNSFEELLKQMRYNDNNSSTRKRANNKCKVQAGKSVSPEDLSPESEMNPDDPEPLSESPEPLPESPEPLPVNPSNELGFISSDEITPVNCQAEVQIDDWVLVYFDQECSHKTKKRGFICQVIVSQHSGTVEEDREDELDEDDEIRCVVCASVFQDIYQLEDHLITGHRYPPDQYRCESCSQTFCWRPHLNFHQAQVHGRKFPCENCTKVFSDPSNLQRHIRTHHVGARQHACQECGKTFATSSGLKQHTHIHSSVKPFRCEVCHKAYTQFSNLCRHKRMHANCRMQIKCVKCDQSFSTVTSLSKHKRFCDSTTPGTTPSGQNSLSAMSHQTPGIPNPYLMYPRPGGTLPFYPPSLMPPYPGLFQPNQTPTPHHPFLSNPLLFNQSMKSNEELDRAKININLSVEAYYRFQLQKNVQQSEEKRKNSPSPRKSDVPKTSGGKLFEFSESKDSPPTAEEANSNQRPSPARPTISASNAVTYPDPREQLEVVTTDVKSDVNQKPRDKLTNFSIDKLSGKMDSQKDEDASEESKPKKAKYCDQPLDLSIASKSSIDSDKQDTNDTFVKTPATSPDIGLMNGINNSLGVNRTPYEHLLRSQISPYANKPFQEILTSQNNAVNGSSSKTTKDRYACKYCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKEKPFKCPLCDRCFGQQTNLDRHLKKHEADDGSGLVSMADSPESSNENEREDAYFDEIRSFMGKVTYSGDVAYNQENLYTGTNPPSPLIDVKDDDDNESEFLSDETEDTFIPQDFRKSPSEIENGSPISYSLKTKGDQEIINNNTSSAADAITLHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -