Dmen001211.1
Basic Information
- Insect
- Diaphora mendica
- Gene Symbol
- pol
- Assembly
- GCA_949125395.1
- Location
- OX421310.1:14929638-14933233[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.17 23 7.1 0.2 2 23 380 402 379 402 0.96 2 12 0.00029 0.039 15.8 1.6 2 23 407 428 406 428 0.97 3 12 0.24 32 6.7 3.2 2 23 432 452 431 453 0.94 4 12 0.93 1.3e+02 4.8 0.6 1 23 458 481 458 481 0.92 5 12 0.13 18 7.5 0.1 2 23 539 561 539 561 0.94 6 12 0.14 19 7.4 6.3 1 20 583 602 583 604 0.91 7 12 0.00011 0.015 17.1 1.3 1 23 612 635 612 635 0.97 8 12 2.4 3.3e+02 3.5 0.9 2 23 641 663 640 663 0.87 9 12 0.0038 0.51 12.3 0.4 2 23 673 694 672 694 0.94 10 12 0.22 29 6.8 0.1 2 23 719 739 719 739 0.94 11 12 0.0076 1 11.4 0.5 3 23 746 766 744 766 0.91 12 12 2 2.7e+02 3.8 0.6 3 23 772 791 771 791 0.90
Sequence Information
- Coding Sequence
- ATGGTGTCATCGCTAGTAGTTGCCGCACCAAGGCAGACTTCAACGGAATCTATCTCATCTATTCGCACTACCAAAAACGACACCATTAACCATCGCCTTCTACGAGAGTATCCTGACGTCACCCGACCTGCAGGTAGACCTGCCCCTGTCAAGCACTCGACAGTACATTATATTCGTACTACACCTGGCCCACCTGTATCCAGTCGTCCACGTAGCTTAGACCCTGAGCGCCTAAAGATCGCGAAGCAGGAGTTTGAGAATATGGTGCAAAATGGAACAGCCCGTAGATCTGACAGCCCATGGTCCTCACCGCTTCATTTGGTGAGGAAGAAAAACGATGGTTGCCGTCCATGTGGGGATTACAGAGCATTAAACTCACGCACGATCCCAGATCGGTATCCTGTCAAGAACTTACAGGATTTCACTCGTCAACTGGCAGGCAGTACAGTCTTCTCCACAATCGACTTAGTTAAGGCGTACCAGCAGTTGCGTTTAATAGACGATGAAGGTGTTTGTGGTGAACCAATATATGAAGTTCTGACAGCTGATGAAACCGACAAGGAAGTGGACAAGATACAAACAGCGACACAGACTGACGCTACACCAGCCGAGAAAACAGCCCCGACGTGTGACAAGTACACCAATAAGGAATACTGGAAATTGAAGCTGAAGCACATCCTCCACCACACGCAGTTCTGCGGAGTCTGTTTGGAGGCTGACGTCGACATGAACGCGCTCTCCCATGTGTTTGAGATCACTAATGAGGAAAGGACTTTGAGCACATCTCTCGCAGACATTGTACATAAGGTCTTCAGAGAGGGTGGGTATTGGCCGGCTAACTCACAAATATGCAACAATTGTACCAAGAAACTAATTCaatcttatatatttatacgcAATGCTGAAAAGACATCGAGAATGCTGGAGCGTCACTTAGATGAGTTGTATACTAAAACTTGCTACGTGCGAAACAATTCGCTGAAAGATGCCAACAGCCCACAACCAAGGATATACAATGTTGTTATTGCATTAGACAATAAAGTGATTTCACAGAACTTTGaaagtaatgaaattaaaatagaaacaccGGAACCAGTGCAAAGTGAAAGAAGTAAGATTCGTGCCAAAAGGAAACTGAGGTGTGTGAGTTGTAATGTGGTTGTACGGTCGTACAGAGCTTGGAGGAGGCACGAGAGAACAGCTCACAAACAGACTGTCAGATGTAGAATATGTCTCCAGAGCTACAAGACACAGCGGGCCTTGACTACACATTACAGGACGCATTTGAGGTCGCGCTGTCCGTTTTGTCACAGAACTGTGCGAGATGGTGCACTGTTGCAACATTTGAAGACGCACCACAAACACTCGATACACTCGTGTACGACGTGTAATGTCGCTCTCTACTCCGCCGAGGCTCTAGGGACTCATATAGAGGAGTGTCATCGTAGAGAGGGTTCTAAATGTGTGACGTGTCTGCAGAGTTTGTCGCGAGTCGAGTTGGAGCGGCACCAGTGCAGGTTCAAGTGTCCGGAGTGTGAGGAGTTGCCTTGTGTCCATCACCGGCACCTGACGTGGTACAGAGAGCAGATGGACCTGGACCCTGGACCCAGGGCCAAGTGTGCGGACTGTCGCTACGTGGCGTCCAGCAAGCAGGCGCTGTTAGCCCACGTCAACGCAACACATCTCAGTGGACAGCGCCTCTGTCGGCCAGCTCTGACTGCATCTGACAACGACAACAAAGATCTCCACGAGTGTCGATATTGTGACAAGACATTCAGCAATTTGTACATGTGTAAACGACACGAGAAACACTGTGAGGGTATTCAAAGGAAGTATCAATGCGACGATTGTCCAACTAATTTTGATTCGACAAAAGATCTCATGAAACATAGAAAACTTAAGCACCGCAAAGAGTTCCTCTCGTGCAGGTTGTGTGACAGAGTGTTTCTAAACAATCTGAAGAAGACGAGACACGAACGGCAAGCCCACGGCGAAGAGCGAGGAAGGGCGAGCTCAGTCTGTGCGGCGTGTCACACTGAGTTCTCCTCGAAGGCGGCCTTGGATCTGCACATGAGATACCATGGAGCTGAAGCAAGGGGTCAGCTCGACAGCTTGGGACagttaaaaagtaacaaacacagACGTTCGTTTGCGGTGTGCGAAGTTTGTGGCGCAGTGATGAGGCGGATTCTTTTGAAGAAACACATGAAAGGCCATTCTATGGCGACAGTGTCGTGTAAACCGTGCGGCAAATCCTTCCAGAGCTCGACTTTACTGAGACATAATCAGAGTGTTCACACGAGGACTGCGCCGTGTCCTAGATGTAAGAAATTGATCAGTTCTGCAAAGTTATGGCGACACTTCAGGAATCACCTCATTCGAGACTCTCTTAATGTCAAACTTGCTGCAATATATACTCTGTGA
- Protein Sequence
- MVSSLVVAAPRQTSTESISSIRTTKNDTINHRLLREYPDVTRPAGRPAPVKHSTVHYIRTTPGPPVSSRPRSLDPERLKIAKQEFENMVQNGTARRSDSPWSSPLHLVRKKNDGCRPCGDYRALNSRTIPDRYPVKNLQDFTRQLAGSTVFSTIDLVKAYQQLRLIDDEGVCGEPIYEVLTADETDKEVDKIQTATQTDATPAEKTAPTCDKYTNKEYWKLKLKHILHHTQFCGVCLEADVDMNALSHVFEITNEERTLSTSLADIVHKVFREGGYWPANSQICNNCTKKLIQSYIFIRNAEKTSRMLERHLDELYTKTCYVRNNSLKDANSPQPRIYNVVIALDNKVISQNFESNEIKIETPEPVQSERSKIRAKRKLRCVSCNVVVRSYRAWRRHERTAHKQTVRCRICLQSYKTQRALTTHYRTHLRSRCPFCHRTVRDGALLQHLKTHHKHSIHSCTTCNVALYSAEALGTHIEECHRREGSKCVTCLQSLSRVELERHQCRFKCPECEELPCVHHRHLTWYREQMDLDPGPRAKCADCRYVASSKQALLAHVNATHLSGQRLCRPALTASDNDNKDLHECRYCDKTFSNLYMCKRHEKHCEGIQRKYQCDDCPTNFDSTKDLMKHRKLKHRKEFLSCRLCDRVFLNNLKKTRHERQAHGEERGRASSVCAACHTEFSSKAALDLHMRYHGAEARGQLDSLGQLKSNKHRRSFAVCEVCGAVMRRILLKKHMKGHSMATVSCKPCGKSFQSSTLLRHNQSVHTRTAPCPRCKKLISSAKLWRHFRNHLIRDSLNVKLAAIYTL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00442067;
- 90% Identity
- -
- 80% Identity
- -