Basic Information

Insect: Diaphora mendica
Gene Symbol: ush
Assembly: GCA_949125395.1
Location: OX421317.1:26727559-26731732[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0079 1.1 11.3 0.2 1 20 109 128 109 130 0.94

2 9 1.9e-05 0.0026 19.5 1.7 1 23 168 190 168 190 0.99

3 9 0.076 10 8.2 0.3 3 20 221 238 220 240 0.93

4 9 0.019 2.5 10.1 3.9 2 21 483 502 482 503 0.95

5 9 0.016 2.2 10.3 0.2 3 20 532 549 530 551 0.91

6 9 1.9 2.5e+02 3.8 0.1 2 23 580 601 579 601 0.94

7 9 0.0095 1.3 11.1 1.3 1 23 607 629 607 629 0.99

8 9 0.09 12 8.0 1.1 1 23 668 691 668 691 0.96

9 9 0.12 17 7.6 0.5 2 20 724 742 724 744 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0079	1.1	11.3	0.2	1	20	109	128	109	130	0.94
2	9	1.9e-05	0.0026	19.5	1.7	1	23	168	190	168	190	0.99
3	9	0.076	10	8.2	0.3	3	20	221	238	220	240	0.93
4	9	0.019	2.5	10.1	3.9	2	21	483	502	482	503	0.95
5	9	0.016	2.2	10.3	0.2	3	20	532	549	530	551	0.91
6	9	1.9	2.5e+02	3.8	0.1	2	23	580	601	579	601	0.94
7	9	0.0095	1.3	11.1	1.3	1	23	607	629	607	629	0.99
8	9	0.09	12	8.0	1.1	1	23	668	691	668	691	0.96
9	9	0.12	17	7.6	0.5	2	20	724	742	724	744	0.92

Sequence Information

Coding Sequence: ATGGCCGCTTTGTTTTTTCCTCTACgtGAGGACGAGGAATGGGGAAACGAGAGCGAGGCGATGCCGGGAGAACCTCGCACACCAAGCTCAGGAGCCGAGAGGGCTGCTTCCAGCGGAGGTGCATCACCTGCGTCTGGAGGTTCGCCCGATGCGTCACCGCCTCGAATACGCCTAAACGCCAGTCTCGCTACAGACCCTGCACTCGCTCCGCAAGCGACGTCGCTCAAACGGGAGCCACCTTCACCATCGCCGCCGCCACCACCTGCTCCGCAGGCACGAACGGATTATCTTACCTTCCCTGCGTTTCTGTCTTCTCCCCCAGGTTACATTTGTAAGCCTTGCGGTATTCGCTATTCATCCCTTAGTACATTACAAGCTCATCAAGAACACTATTGTTCAAATAGAAGGCCTAAACCCACAGAAGCTACAGATACACCAGCTGATCCAGCTGTAGATGAATCCAGTAGCGATGCAAAGACACCCCGGCCTCCTAGCAAGCAGTATACTTGTACCTACTGCAATTACAGTGCTGATAAAAAAGTCAGTTTGAATAGACATATGAGAATGCATTCCTCGTCCCCTGTGAGCAGTGGAACCCCGGTACCCACACCAGCGTCAAACGGTGAAGTCACCGAGAGTCCACCCATACAGGATCGCTATTGTGCTGATTGTGACATCCGCTTCAGCTCTATAAAAACATATAGAGCTCACAAAGCGCATTACTGCAGTACAAGACAGGTTGTAAAACCAGTTTTAGCCACCGCTAGAGGTGGCTCTGCCACATCAGGGTCCTCACCGCCATCTCCAGGAGCCACGCCTCCTGCACAAAACTCGCAATATGCACTTGCTTTGCCGACAAATCCAATTCTTATTGTGCCCTACTCTTTGTTAAGAGGAGCCAGTACTCTCCCAGGTGCTACATTGCCTGATCCAGATACACCTTGCTTTTTGTTACCAAATGGAACATTTCAGCCAATAAGCCGTGCTTTGTCTTCGTCTGGTGCCACCGCTGATGGAAAGGAATCTGACGTTTTAAAAGCAGCTAATAGGCCAAGAGAGGCATCAAGAGATGGTGCTACTCCTTTAGATCTCAGTGTGCGCCGTTCCCCAGAATCCGTAGTGGCCGACGAACATGAGAAAGAGAACAGAATACGATCGACAACACCCGAGCAAATCGTATGTGCCCCATCGTTACCAGGATCTCCAAGTACTCCATCTCCGTCCCGGCGATCTTCATCGCCGAGTGGAGAAAGTTCACCAAAACGAAAACGACGCAATTCTAGGGGACCGACTCCAAAACCTCCTAGTGTGGCATCGCCTCCAGAAGAAAAATTCGCCCCTGTAATTGCACCTGCAATAATACCCCCTGCCCTAGCACTGCGCTTGGCAACAGAGTTACCTTTAAATGCAGTATCTCCTCAGGTTCTTGTAAAACAAGGGGTATCAAAATGTAAAGAATGCAACATAGTGTTCTGTAAATACGAAAACTATCGAGTTCATAAACGGCACTATTGTTCAGCTGGTGCAGGTGATGAGCGCGTTAGTCCGGCACCACCAGAGCCGGGCCCACCGCCGCAATACCGGCAGTTGATCTGCGTGGCATGCGGCATTCATTTCAATTCACTGGACAATCTGACGACGCACCAGTCGTTTTACTGCACAAAACGGGAGACACGGTCACCTCGTAGCGCCCCTACCGAGACTCCTCGACCAACGTCTGGTTCGGAAGGTGGCTGGAAGTGTCCTTGCTGTGACATGGTATCTCAAACTGCAGCGGCTGCACAACGTCACATGGAGGCCCATGCTGGAGTCAAGGCCTTTCGCTGCACTATTTGTCGATACAGAGGAAACACGCTACGAGGCATGCGTACGCACATACGCATGCACTTCAACAACAAGAAGCCTGCTGACTTGCAGGAAGAAAGCTACATCGCTTGCGTTATCGAAGAAGACAGTCGCGAGACGACATCTCCAAGCCCAGCTGTGGGCGGCGAGCGAGTTCATCGCTGCAGCAACTGTGCCTACACCTCTACTTACCGAGGCAACGTAGTCCGGCACGCTCGCCTTGTCCACGCCACCGATGAACCAGAGGAAGAACAGAGCTCGCCTCCTGTTCCACCAGtagacataaaaaaagaaccagAAACGGAAATGGAGGAAACTCCAAACTACTGCAAGTCTTGCGACATTTCGTTCAAGTATGTGGAAACTTATAAAGCGCATAAGCAATTTTATTGCACTGCGAACAACCAGGATGCTGCTGCAAATAATAACGTACCAACACCAACGAGAGTCACTGATACACCTATAGTATGA
Protein Sequence: MAALFFPLREDEEWGNESEAMPGEPRTPSSGAERAASSGGASPASGGSPDASPPRIRLNASLATDPALAPQATSLKREPPSPSPPPPPAPQARTDYLTFPAFLSSPPGYICKPCGIRYSSLSTLQAHQEHYCSNRRPKPTEATDTPADPAVDESSSDAKTPRPPSKQYTCTYCNYSADKKVSLNRHMRMHSSSPVSSGTPVPTPASNGEVTESPPIQDRYCADCDIRFSSIKTYRAHKAHYCSTRQVVKPVLATARGGSATSGSSPPSPGATPPAQNSQYALALPTNPILIVPYSLLRGASTLPGATLPDPDTPCFLLPNGTFQPISRALSSSGATADGKESDVLKAANRPREASRDGATPLDLSVRRSPESVVADEHEKENRIRSTTPEQIVCAPSLPGSPSTPSPSRRSSSPSGESSPKRKRRNSRGPTPKPPSVASPPEEKFAPVIAPAIIPPALALRLATELPLNAVSPQVLVKQGVSKCKECNIVFCKYENYRVHKRHYCSAGAGDERVSPAPPEPGPPPQYRQLICVACGIHFNSLDNLTTHQSFYCTKRETRSPRSAPTETPRPTSGSEGGWKCPCCDMVSQTAAAAQRHMEAHAGVKAFRCTICRYRGNTLRGMRTHIRMHFNNKKPADLQEESYIACVIEEDSRETTSPSPAVGGERVHRCSNCAYTSTYRGNVVRHARLVHATDEPEEEQSSPPVPPVDIKKEPETEMEETPNYCKSCDISFKYVETYKAHKQFYCTANNQDAAANNNVPTPTRVTDTPIV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00050390;
90% Identity: iTF_00405472;
80% Identity: -