Dmen015104.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diaphora mendica
Gene Symbol
L
Assembly
GCA_949125395.1
Location
OX421315.1:17017792-17045026[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.7e-06 0.00023 22.9 1.7 1 23 87 109 87 109 0.99
2 16 0.71 96 5.2 5.8 1 23 115 137 115 137 0.97
3 16 9.6e-06 0.0013 20.5 4.1 1 23 143 165 143 165 0.99
4 16 3e-05 0.004 18.9 0.1 1 23 171 193 171 193 0.98
5 16 0.0014 0.18 13.7 0.0 2 23 209 231 208 231 0.94
6 16 6.8 9.2e+02 2.1 0.1 9 23 262 277 258 277 0.93
7 16 0.34 46 6.2 0.0 3 23 330 350 329 350 0.97
8 16 0.16 21 7.2 0.0 2 23 364 385 363 385 0.91
9 16 0.00062 0.084 14.8 0.3 1 23 393 416 393 416 0.95
10 16 0.11 15 7.7 0.0 1 23 421 444 421 444 0.92
11 16 0.04 5.4 9.1 0.1 1 23 505 529 505 530 0.93
12 16 0.00022 0.03 16.2 0.1 2 23 591 612 590 612 0.96
13 16 0.066 8.9 8.4 0.0 1 23 620 642 620 642 0.97
14 16 0.99 1.3e+02 4.7 0.3 1 23 746 768 746 768 0.94
15 16 0.004 0.53 12.3 0.1 1 20 776 795 776 798 0.95
16 16 0.17 23 7.1 0.3 1 23 805 827 805 827 0.94

Sequence Information

Coding Sequence
ATGGGTAAAAGAATTTTAAGGCGTCCGTGGACGCCTGAAACAACAGTGAATACCTGGTTCACCATTTTAGTCACTCTAATCAAATTAGGAGGAAGGAAGATCGAGGCGCTGGGCAGCGTGGGCAGTACGGCGGGTAGCTCTTGGCCGTCATCGACGCCGGAGCCGTCACCGTCACCAGCTTCGACGCCGACATCCGCCGATGCAGCCGATGGCGAAGCTGAACCGCCATTTACGCTTGGTGCCACCGAGCATACTCCgtatcaatgtcaattctgTGACAAAGCGTTCCCTAGACTCTCTTATCTGAAGAAACATGAACAGACACATTCTGACCAGATGCCGTTTCGGTGCGAGTTTTGCTCACGACTTTTCAAGCACAAGCGTTCCCGGGATCGCCACGTAAAGTTACACACCGGAGATCGCAAATACAGATGCGCACATTGCGAATCAGCGTTCTCCAGGAGTGACCACTTAAAGATTCATATGAAGACCCACGACAACCAAAAACCCTTCCAATGTACTGTGTGCAACCGCGGGTACAACACTGCAGCAGCTCTGACGTCACACATGCAGGGGCATAAACGGGATCGCGAAGGACGAGAGCCGGACAAACGGCGAGCTTTAAGGTGTTTGAGATGCGGCGATGCCTTCCGAAGACCTGACTTATTGCAGGCACATATGGTGAGCGCCCACTGTGTCGATGGTGCTGCGATGACACCACCTCGACGAGTCGCCTCTCAGCCACCACCCACCCTACTTGCCTGCATTTACTGCACGCGAGACACATTCACTAGCATGGAGCAACTACAACTTCACGTCCGAGCTGCGCATTCCGCATTACTCAACGGTGACCCACCCTTACAATCTGTGGAACAACCCGCACCGACTGATCTTAGTCGACGTGCGACCGAAGATGGGCCACAAGTAAAACGTCCTCGTTCAGGCTCTGGCACACCTCAAACGACGTTATCACCCAACACCTTATTATGCAACCAATGTGACGCTGCTCTGCCTGATTTCGAAGCATTTCGTGCTCATCTGAAAGGGCATCTCGAAGAAGGAGGAGAATTAAGTCGATCGAGCCCCGTTCCCTGTGTTCATTGCGGAGCAACATTTGCGGACGCAGCGGCCTCAGAACGACACCTCACAGCGCATTACTTGGCCGTCTCGTGTGAATACACTTGCCATAGTTGCGCTCGAAGTTTCGCTGCGCCGGATGACTTGCAGAAGCATCTTCTGGAATTACATGCACATCATCTGTACCGTTGCGCTTTGTGTAAAGAAATATTCGACTCTAAAGTCGCTATTCAGGTGCACTTCGCAGTGGCTCACAGCGGGGAGAACAAAGTATGGGTTTGTCGTTCGTGTGGGGCGGGTGGTGGTGCTCTGCGGTCGGAGGCGGAAGGCGCAGCGCACGTGCGCGCGCGCCACGCAGCGGCCGCCCCGCGCTGCGCGTGCGGCGCTCTGCTCGCCGGCGCCGCCGCCGCGCGACCTCCGCGGCACCACCGCGCCTACCGCTGCCCGGTACCTGCCTGCAGCGACGCCTTCGCCGTGCAGTACCTACTGGAGAGACACATGCAAGCGCACCACGCCGTGCCTCATCAGGTCATGAATGGTGAAGTAACAAGACCCAAAAGAGTAGACACTAGTAACAGCGGAGATCCAGTTGATGGAGAGCGATCTCCTTGCACCCCTGGGACCGAAAATGGAGGCCAGGTTGGGGCGCCAGCTGGTGAAGAACGTCGCCGTAAGAACGGAGCTGTTGCACTTCAATGTGCGTATTGTGGAGAACGAACCCGTAGCCGCGCAGAACTAGAAGCTCACACTCGAGCACATTCAGGAGCCGCCGCCGCTCGACACAAGTGCTTGATTTGTGATGAAGTTCTACCTTCAGCTGCGGTACTCGCCGAGCACAAGCTCACCCATTGCAAGGTGGTTgcaggcgatacgtgtgctcgttgcCGCGCAAGATTGCTGTCTGAAGAATCTTTCCTAAATCATATGGCTCGTCATCATCCTGCACTTCCAGCTCCCTGCGTCGTGTGTCGACAAACATTAGCTTCGGAAGCTGAAGCGCGTCTCCACGCGCGTTTCCATTTACGACCAGGAGATGATGAACAGAGATGTGCGATATGTCTTCGTGCACTTCCTGAAGGAGAGGCTGGTGAGGGTGCAAGAGCGTGTTCAGCGTGTTACGCTCGTCATGCCGCTCCAAGACTCCCGCCGCCGGCAGATCACGATTGTCGTCTTTGTCGACGTGCTTTAGGATCACCCACGCGATTACAAGCGCATCTTATCGAACACACGTTTGCTGGTATCGGAGCATTCACCTGCTACCTCTGCTCAGCTGTATTTACAAGTGCAGCAGGCCTCCAACGTCATCTTCCAGAGCATGCGTCAGCACCACGACCCTACGACTGCGCGCGATGCGGGTTGAAGTTTTTCTTCCGCGCCGAACTTGACAATCACGCCTTTGTCCATCTTGAAGAGGCCGAGATAGCTCAACGTGCTTTTTATGAAGCGTATGCTCGTGGAGCGGCCTCGGCTTGGGCTGCTCTAGCGCCTTCTGAACCACCACGCTCTTCTACGCCGCCTCCTGAAGTGAAACTAGAGACGGAGATAAAGGAAGAAAGAGGAACTGATGAATACATTGAAGTGTCGTCACCGCCGCCTGCTCAAGCACCCCCCGCACCTCTTGCACCTCCCACACCCTCGCCCGTTATTAAGCAAGAAAAACCTGACGAGGAGTAA
Protein Sequence
MGKRILRRPWTPETTVNTWFTILVTLIKLGGRKIEALGSVGSTAGSSWPSSTPEPSPSPASTPTSADAADGEAEPPFTLGATEHTPYQCQFCDKAFPRLSYLKKHEQTHSDQMPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDREGREPDKRRALRCLRCGDAFRRPDLLQAHMVSAHCVDGAAMTPPRRVASQPPPTLLACIYCTRDTFTSMEQLQLHVRAAHSALLNGDPPLQSVEQPAPTDLSRRATEDGPQVKRPRSGSGTPQTTLSPNTLLCNQCDAALPDFEAFRAHLKGHLEEGGELSRSSPVPCVHCGATFADAAASERHLTAHYLAVSCEYTCHSCARSFAAPDDLQKHLLELHAHHLYRCALCKEIFDSKVAIQVHFAVAHSGENKVWVCRSCGAGGGALRSEAEGAAHVRARHAAAAPRCACGALLAGAAAARPPRHHRAYRCPVPACSDAFAVQYLLERHMQAHHAVPHQVMNGEVTRPKRVDTSNSGDPVDGERSPCTPGTENGGQVGAPAGEERRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDTCARCRARLLSEESFLNHMARHHPALPAPCVVCRQTLASEAEARLHARFHLRPGDDEQRCAICLRALPEGEAGEGARACSACYARHAAPRLPPPADHDCRLCRRALGSPTRLQAHLIEHTFAGIGAFTCYLCSAVFTSAAGLQRHLPEHASAPRPYDCARCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAASAWAALAPSEPPRSSTPPPEVKLETEIKEERGTDEYIEVSSPPPAQAPPAPLAPPTPSPVIKQEKPDEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01437318;
90% Identity
iTF_00822228;
80% Identity
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