Basic Information

Insect: Diaphora mendica
Gene Symbol: Znf296
Assembly: GCA_949125395.1
Location: OX421312.1:17195268-17214804[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.14 19 7.4 2.7 2 20 48 65 48 69 0.92

2 12 0.032 4.4 9.4 0.2 2 23 107 128 106 128 0.96

3 12 2.6 3.4e+02 3.4 1.4 3 23 200 221 199 221 0.94

4 12 0.022 2.9 9.9 0.2 2 20 227 245 226 247 0.92

5 12 0.00012 0.016 17.0 0.9 1 23 255 278 255 278 0.98

6 12 0.00019 0.025 16.4 4.5 1 23 299 321 299 321 0.98

7 12 9.1e-06 0.0012 20.6 4.5 1 23 328 350 328 350 0.98

8 12 3.9e-08 5.3e-06 28.0 0.7 3 23 364 384 363 384 0.98

9 12 2.3e-05 0.0031 19.3 3.2 1 23 390 412 390 412 0.99

10 12 2e-06 0.00027 22.6 2.6 2 23 419 440 418 440 0.96

11 12 1.1e-07 1.5e-05 26.5 1.5 1 23 446 468 446 468 0.99

12 12 0.0028 0.38 12.7 0.1 1 23 474 496 474 496 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.14	19	7.4	2.7	2	20	48	65	48	69	0.92
2	12	0.032	4.4	9.4	0.2	2	23	107	128	106	128	0.96
3	12	2.6	3.4e+02	3.4	1.4	3	23	200	221	199	221	0.94
4	12	0.022	2.9	9.9	0.2	2	20	227	245	226	247	0.92
5	12	0.00012	0.016	17.0	0.9	1	23	255	278	255	278	0.98
6	12	0.00019	0.025	16.4	4.5	1	23	299	321	299	321	0.98
7	12	9.1e-06	0.0012	20.6	4.5	1	23	328	350	328	350	0.98
8	12	3.9e-08	5.3e-06	28.0	0.7	3	23	364	384	363	384	0.98
9	12	2.3e-05	0.0031	19.3	3.2	1	23	390	412	390	412	0.99
10	12	2e-06	0.00027	22.6	2.6	2	23	419	440	418	440	0.96
11	12	1.1e-07	1.5e-05	26.5	1.5	1	23	446	468	446	468	0.99
12	12	0.0028	0.38	12.7	0.1	1	23	474	496	474	496	0.97

Sequence Information

Coding Sequence: ATGGAGTGCCCAGTGGGAGTCAAGACTGAAGATATGTTACTAAATGATCATGATGACTATACTGATGGTGATTACAGCATGTCCCTGAGTAGTGGAACAGATTTAAATGATTTGGttgAATGTGATGATTTAAATGGCAACTATTGTCCGCTGTGTGGCGTATGTTATGATGAGGAAAGTTTAACTAAACATATGTGGAAGTGTCATTCAGATGTTATGGGCCCCAAGAAAAGAGGCAGGCCGAAGAAATTATTGACAAGTACAATTATTGACAAGTTATCAGAAAACGGATTTTTTATCACATCTTTAAAAAAAGTCGAATGCTTATTTTGCAAAGAGTATTTTGGCACCAAAGAAGAATTAGGAACTCATCTGTTAAGCCATAAAGATATGAATATATTATGTTGTGAACTATGTAAAAAGATGTACCTGGAACGAAAAAATATTGATCAACACAGTTGCAGTCCTGGAAAAGTTgttGATCTGCCCAGAACAGAAGGAGTCGAATTGAAACAATTTAGCTTCTATtcagaaataaaattacaagAACTTATCGAATCCAACACTGATCtggaaAATATCGCATTACTGCAAATATGTAGCGCATGCGGGTGTGTATTTCTATTTGAAAAAGATCTCATTAATCATCACGATACTGAACATCCAGAACTGTCAATGCGTTGTAATTTCTGTACGAAGGTGTTTGCCACTTTGAGGTCGGCTGCTCGTCATAGAGACGTATGTAAAgaaattgaaagaaaatataaatgtacaacCTGTGGACTTCAATTTGAATACGAAATATctctaaataaacatattttaaggTATCACAAAGGCCAAAGCGTGTCTGTCAAATTCATTGACACGAAAACTAAACGTGATGAGAGACAATTCCAATGTGATACTTGCAGTAGATGTTTCTATAAGAGGGATTTACTAGTTAGACATACCAAAATACACATGCCCAACGAAAAAAGTTTTGAATGCGATGTTTGTAAAAAACGATTCCATAGAAGAGATAATTTACGTTCTCACAAGCGGGTACATGAAGTGGCGCGCGATAAAGGTTCTCCAAGCTCATCCTTGTGCCTATACTGCGGCCGCAGTTTCTCTAATTCATCCAACTTGATAGTGCACATGCGTCGTCACACAGGAGAGAAACCTTACAAATGTGATTTTTGCGGCAAAGGATTCCCAAGATCATCAGATTTACAATGCCACAGAAGATCACATACCGGAGAAAAACCTTGCATATGTCGTGTTTGTGGAAAAGGTTTTTCTCGCAGCAACAAGCTGTCCCGTCATATGCGGGTCCACACGGGGCAAAGACCGTACAAGTGTACTTATTGCGAAAAGGCATTTTCACAGAGTAACGACCTCACCTTGCACATTAGGAGACACACTGGTGACAGGCCTTACATCTGTGAAGTATGCGGAGATAGATTCATTCAGGGAACAGCCTTGCAGAATCATAGGCGAGCTCACGGCCACTTTCCGCCAACGCCTGCTGAGACTCCTGCCGTGGTTCAAGCTCTCACTTATGCGGTTCAAACCATTAACCACAGTAGTCACTAA
Protein Sequence: MECPVGVKTEDMLLNDHDDYTDGDYSMSLSSGTDLNDLVECDDLNGNYCPLCGVCYDEESLTKHMWKCHSDVMGPKKRGRPKKLLTSTIIDKLSENGFFITSLKKVECLFCKEYFGTKEELGTHLLSHKDMNILCCELCKKMYLERKNIDQHSCSPGKVVDLPRTEGVELKQFSFYSEIKLQELIESNTDLENIALLQICSACGCVFLFEKDLINHHDTEHPELSMRCNFCTKVFATLRSAARHRDVCKEIERKYKCTTCGLQFEYEISLNKHILRYHKGQSVSVKFIDTKTKRDERQFQCDTCSRCFYKRDLLVRHTKIHMPNEKSFECDVCKKRFHRRDNLRSHKRVHEVARDKGSPSSSLCLYCGRSFSNSSNLIVHMRRHTGEKPYKCDFCGKGFPRSSDLQCHRRSHTGEKPCICRVCGKGFSRSNKLSRHMRVHTGQRPYKCTYCEKAFSQSNDLTLHIRRHTGDRPYICEVCGDRFIQGTALQNHRRAHGHFPPTPAETPAVVQALTYAVQTINHSSH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01152409;
90% Identity: iTF_01360919;
80% Identity: -