Dmen005033.1
Basic Information
- Insect
- Diaphora mendica
- Gene Symbol
- -
- Assembly
- GCA_949125395.1
- Location
- OX421311.1:9410665-9413705[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00066 0.09 14.7 1.6 1 23 38 61 38 61 0.94 2 19 6.2 8.4e+02 2.2 0.8 6 23 93 111 92 111 0.92 3 19 0.029 3.9 9.6 0.2 2 23 134 157 133 157 0.91 4 19 0.26 36 6.5 2.8 1 20 158 177 158 179 0.92 5 19 2.4 3.2e+02 3.5 0.7 2 23 183 205 182 205 0.92 6 19 0.00016 0.022 16.6 2.4 1 23 209 232 209 232 0.97 7 19 0.0013 0.18 13.8 2.3 2 23 239 260 238 260 0.95 8 19 2.1e-06 0.00028 22.6 1.0 1 23 266 288 266 288 0.98 9 19 5.4e-06 0.00073 21.3 1.1 1 23 294 316 294 316 0.96 10 19 0.0064 0.87 11.6 0.8 1 15 322 336 322 338 0.91 11 19 0.00036 0.049 15.5 1.1 1 23 426 449 426 449 0.95 12 19 0.029 3.9 9.5 1.3 2 23 480 501 479 501 0.95 13 19 0.0091 1.2 11.1 3.6 1 23 522 545 522 545 0.97 14 19 0.003 0.41 12.6 0.1 1 23 550 573 550 573 0.92 15 19 0.00011 0.015 17.1 0.9 1 23 578 601 578 601 0.97 16 19 0.28 38 6.4 0.9 2 23 607 629 606 629 0.93 17 19 2.3e-05 0.0031 19.3 4.9 1 23 637 660 637 660 0.98 18 19 0.015 2 10.5 2.4 1 23 666 688 666 688 0.97 19 19 3.8e-05 0.0051 18.6 1.7 1 23 694 716 694 716 0.98
Sequence Information
- Coding Sequence
- ATGGCCAGCAATCACATCGGCACAAAagcggaaattatcaaattaaaatctTACTTTAATAAAATCCTTCAACTATCCACCGCCGTACCTTTTAAGATACACGAAAACGAATACCAATGCTTCTATTGTGATAAAACGTTTCTTCAGCCATCTAAACTAAGAGAACATAGCACTAGGGCTCACAGCTTAACACAAGCTGATACTCAACTAATTTGGCCTAAATTCAACTTCGATTCCAGCGTAATGTtagacataaaaatatttaactgcATACCCTGCAATTTTAAACTTTCTAACTTGCACGATTTAAAATCCCACTTCAAAGAAATACATGATGAAATTCCTCCAAAAGATTTACTGGACAAAGTTATGTGTTACAAACTAAATGACGATTATataaaatgtgttttgtgtTCACGAGGTTTCTATGACGTTCAGAATCTTCTAGACCATCAGAAATCAAGCGTTCATTTCACTTGCCAAAACTGCAAAGAAAATTATTGCAATAAACAGGAATTTCTTGAACATGAAACGACATTTTGCAAGCCTTGCACCCTTTGCGATTTGAGATTTCTATCAAAGAAACAAAGGGACGCACACTTAAAAAATGTCCACTCCCAAAGGTTTAAATGTCAGTTTTGTTCACTAAAATTCACTTTGAAAGAAACGCTAACTCGTCACATCAGGAACATCCACtataaagagaaaaataaaacatgtgATGTCTGCGGCAAAAGTTTTTTTGACACTCATTATCTCAACTTGCACAAAGTAAGTCATCAAAGTACAAAACCCTTTGAATGTGACATTTGTAAGAAGAAATTCGCTCGCAAAGAAGCATTGAAACTACACAAACGAATTCACAATAACGACAAACGATATAGTTGCAAAGATTGTGGCAAAAAGTTTATCCAATGGTCAGCTTTACATATGCATAAGGTAGTACATTCGGAAGAGAGGAATTTCAAGTGTCCAGTTTGTCAGAAAGCATTTAAAGATAAGAAAACTATGAGCGAAAAAAGGAAGAAGAAAAATACTCTGAAAGACCAGGACTTGTTTGTTACGGAAGAAAAAAGTAAGAAGAGAAAGAGGGTTATCGAAGATGATACTGACTCTTACACTTCACTTGATAtgacaaagaaaaagaaaaaaaacattgaaaaggCAAAGAAAAAAACTGGTGCCGAGGAAGAAGCTAAGAGAGAGACACGGCACCTTCTAACAGTTATTATAGAGACTTCTACAGCGATGCCTTTTCGCAAAAATGGGAACACATATAGGTGCTTCTATTGTGAAACTAATTTTTACTACGCATCTGAATTAAGAGCTCATACTCTGAACGAACACAAAAATGAAACCAAAAGACAATTAAAACAGACCATTAACAGAAACGTTGTTAAAAAGAATCTCATTGTGAAGTTGGATGTGACCAATCTGACATGCAAATTGTGTTCTGAATCTTTTGTCACTCTCAAAGACCTTATATTCCATTTTCGCAAACACGACAAAGTAGTAACTGATAATCTTGAAAACATGTTATGCTTAAAACTATCAGATAATGAATTCAAATGCTTGTATTGCGATAAAGAATTCCCCTTTTTTAAAACTCTGTATATACATTTACACAGAGAGCATGTCAACAGACGCTTCATATGCGATGCTTGTGGTCTCAATTTCACAACCAACCAAGGTTTAAATAACCACACGGCTTATGTACACAACCAGGGTAGTTTTATCTGCCCGGATTGTGGCAAAAAGTTTGCTGCCCAACATCTTCGTAGCGCACATATGAAGCGTTCCCACGATCCAGAAAACATAAAATGCCATGTGTGCAAGGCAATATTCCGAAGTGTTAATCAAAAAGTCACTCATTTGGCGAAGGAGCATAACATTTGGATTACAAAGGAATTTAAATGCGACAAATGCTCAAAGAGCTTCAAATATAATCACATGCTGATGACGCACATAAAACGGGTCCATTTAAAGGAAAAGAACTTTACGTGCGATCATTGCGGGGATAAATTCTTCGAGAGAAAACTGCTAGAGTTACATCAAATAAAACACAGTGACGCCAAACCTTATGAATGCAGAACCTGTAATAAACGGTTTCCGAGGAAGAATGCCTTGTATCGACATGAGAAGATACACACGGATCCTCGTAATTTAGGTCTCAAACGATTGCAGCGGAAGACGTTTGAAGAATCATCGTGCTCACAGCTGTCTGCCGTTATATCATAA
- Protein Sequence
- MASNHIGTKAEIIKLKSYFNKILQLSTAVPFKIHENEYQCFYCDKTFLQPSKLREHSTRAHSLTQADTQLIWPKFNFDSSVMLDIKIFNCIPCNFKLSNLHDLKSHFKEIHDEIPPKDLLDKVMCYKLNDDYIKCVLCSRGFYDVQNLLDHQKSSVHFTCQNCKENYCNKQEFLEHETTFCKPCTLCDLRFLSKKQRDAHLKNVHSQRFKCQFCSLKFTLKETLTRHIRNIHYKEKNKTCDVCGKSFFDTHYLNLHKVSHQSTKPFECDICKKKFARKEALKLHKRIHNNDKRYSCKDCGKKFIQWSALHMHKVVHSEERNFKCPVCQKAFKDKKTMSEKRKKKNTLKDQDLFVTEEKSKKRKRVIEDDTDSYTSLDMTKKKKKNIEKAKKKTGAEEEAKRETRHLLTVIIETSTAMPFRKNGNTYRCFYCETNFYYASELRAHTLNEHKNETKRQLKQTINRNVVKKNLIVKLDVTNLTCKLCSESFVTLKDLIFHFRKHDKVVTDNLENMLCLKLSDNEFKCLYCDKEFPFFKTLYIHLHREHVNRRFICDACGLNFTTNQGLNNHTAYVHNQGSFICPDCGKKFAAQHLRSAHMKRSHDPENIKCHVCKAIFRSVNQKVTHLAKEHNIWITKEFKCDKCSKSFKYNHMLMTHIKRVHLKEKNFTCDHCGDKFFERKLLELHQIKHSDAKPYECRTCNKRFPRKNALYRHEKIHTDPRNLGLKRLQRKTFEESSCSQLSAVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -