Basic Information

Insect: Diadegma fenestrale
Gene Symbol: ttk
Assembly: GCA_037043255.1
Location: CM073314.1:8657501-8674099[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 8.6e-07 7.6e-05 23.1 1.8 1 23 762 784 762 784 0.98

2 8 1.1e-05 0.00099 19.6 2.4 1 23 790 812 790 812 0.98

3 8 2.2e-06 0.00019 21.9 0.3 2 23 821 842 821 842 0.98

4 8 2.6e-05 0.0023 18.5 0.2 3 23 850 870 848 870 0.97

5 8 2.3e-07 2.1e-05 24.9 3.0 1 23 876 898 876 898 0.98

6 8 2.7e-06 0.00024 21.6 2.1 1 23 904 926 904 926 0.98

7 8 8.2e-05 0.0072 16.9 7.5 1 23 932 954 932 954 0.98

8 8 0.00011 0.0095 16.5 1.5 1 21 960 980 960 981 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	8.6e-07	7.6e-05	23.1	1.8	1	23	762	784	762	784	0.98
2	8	1.1e-05	0.00099	19.6	2.4	1	23	790	812	790	812	0.98
3	8	2.2e-06	0.00019	21.9	0.3	2	23	821	842	821	842	0.98
4	8	2.6e-05	0.0023	18.5	0.2	3	23	850	870	848	870	0.97
5	8	2.3e-07	2.1e-05	24.9	3.0	1	23	876	898	876	898	0.98
6	8	2.7e-06	0.00024	21.6	2.1	1	23	904	926	904	926	0.98
7	8	8.2e-05	0.0072	16.9	7.5	1	23	932	954	932	954	0.98
8	8	0.00011	0.0095	16.5	1.5	1	21	960	980	960	981	0.95

Sequence Information

Coding Sequence: ATGATGGGGGAAGTGATAAGAGTATCAGGACGAGCTCCGGATGTCGGTGACCTTCTCCGAGAGGCCATGGTGTCACAGAGATTCGCTGATGTAGCTCTTTGCTGTTCCGGCGGACAGAGATTTTTGGCACATCGACTCGTTCTTTCAGCTGCAAGTCCCTATCTCCAGGATGTTTTTCTGGCCCATGGGAAAGCAGCGGGATCGAGTGAGCCGATAACGATCATTTTGGCGGAAGTGGAAGGTCCAGAATTATCAGCGATATTGGGTTTCGTGTATACCGGAAGTGCGACCATACCAAAATCTCGTTTAGAGGCATTTACACGTGCTGCGGAGACACTTCACGTGAGGATTCCAAAGTTTGGCTCGCCAGTCAGATTGGACGTTGGTAATTACGAAATATTATCATCCTCGTGCAACCGAGATGGCGATTGCAAGTTCGATTGTGTCAAAGTCGAAGAGACTGCGAGATTGAAGGACGCGAGATATTTGCGATGTGAGCAATATCCGTCTTGGGAGGGTTGGCTCAATCCCTCCGACTGGCATTATCATCGGGAATGTACGAGACGTGTTTTCCAGCCTGAAGACTGGATACCaaggaggaaagaaaatggaGCAACTTTACAGAGACAACGCGAAGCCGAAGCGCCGTCGTTTTCCGAGGACGTTGAAGCAACGAGCAGGAAACATTTGCCTCGAGAAAACTTCGATAATTCTTTCTGCATCGAGAGAACATTTGAAAAGAGCGTCGATGGCTTTGAGAGACGGAAGTCTCCGTGGATCGAGGGCGATTCTTCGGTTTCGAATCCCAGCAGCCTTTTCCTCGATCCATCGAAATCGATCCCCGAAATCCGCAAGGAGCCCGAAAACTACGAGTTTCCGGTTCAAGCTCATCCGGGACTCGAAGTTTTCGTTGCTGCGCCATCAAAGCTCGTAGATTCTTTCTCCGCGACCGGAAATTACAGCTCGAGGACAAGCCTCGAGTCCTGCAGAGTTTACGAGGACCGAATCGAGGAAAATCCTCGAGAAAACGGAGATTTCGAGCCTCGAACGAATCTCAAATTCGATAATCATGATTACGAGAATTCTTCCCCATTCTCATCGAAACTTCCAATTAGTCCCTCGTCGAATCTTCAGTCCAGCACGGAAATACTCCCCGAAACAACTGTCTCTTCCAACATCCCTTTACAATTTACTACGAACCTTACAAATTTAACGATTCCAtccaaaaactcaaatttctgCAGCGATAATTGCTGCACGTGGAGAACACCCAAACGACACGTTGCCAATCGTGTGCCAGCTTCGCCTTGGTGCCAACTCGCTCGACCGGCTCATCATTCTCCAAAAACACGGCCCATCCTCCCACGCAATCCGAACGAAAACGTCGAGCCTCCAGTTCATCCAGACTGGAACGGTGCGGTTGTTCCGAACGAAACGCGTTCTCGAGGATTTTCGCCATCGAGGGTGACTTACGTGGACAACAATCAGATCGGTGCTGGGtctttgcatgaaaatttggagGGAAATGGATCGTCGGAAGGTACGGGAGCGATTTATGGTTTTCAAGTTCCTAAAATATCGAGAGGGTTTTCTCCGAATGTCGAGGAATGTGCGGATTATTCGAAACAACCGCGAAGCCaggaggaaaaattttatgacgaaaagtcttacgaaaaatcatcgacatTTCCTGCGCCAGGAAATTTCTCCACGGAGCATTTTCCAGCGAGAACAATCGcgcacgatcgatcgatcgaaaagcCTAGTGCGCTCGTCGATATTCTTCAGGACCAATCGCGTCCTCAGCAAAGCAACGAAGCCTCAAATATCATCTTGAATCACGAACAATCGCGCGTCAGAATTTCTCAACACGCGATCCCACCTCAGGCAAATCCTAACAAGCAAATAATCAACGATCCTCCGTCATGCAATCTTCAAACGTCACCGAGACTCGAACTTTCTCATCCAATAAGTCGACTCTGTGATTCGGTCCGTAATATCGACGATTCCGTCTCccgagaaaaaattttcatcgataaagATACTCCGGAATCTTCGTCCCTGGGCATCCAACCGATCGAATCGAAACTCGAAGGATCTTTGgattttcgaagcaaaacaaACTTGTCCGTTTCTCATGCGATCATACAGAGCgacgacaacaacaacgagCCTGGAATCAACGATCCCGTCCCCGATATTTCAACTAATCCTGATTTTCGTTTAAACGAAGATGTTCATGACAATGTCACGCAGGACGAGGCCACCGGTAACGGCGAGGATCACAGATGCGAACAATGTGGAAAAACTTTCGTCACTCGAGCGTCTCTCAAGGTTCATGGTCGTACACATTCGGGAGAGAAACCATTTCGTTGCACGGACTGTGGCAAGGAATTTTCGCAGTTGCGGAATTACAAGTATCATCGTAGCGTACACGAAGGTACAAGAGAGTTTGCGGCAACATGTCCCGAATGTGGAAAGTACTTCAACGACCGTGGTTATTTGAGTTCTCACATGAAGATCCATCGGAATCGCAAGGAGTACGGGTGTTCGGAGTGCGGCAAGAGTTTCAATCAGCGAGTCGCTTATAACATGCACGTGCGTATACACACAGGTGTAAAGCCTCATCAGTGTGACCAATGTGGCAAAGCATTTTCCCGAAAGATGTTGTTGAAGCAACATTTGCGTACGCATTCGGGTGAACGTCCGTATCAATGCCAAATTTGTCACAAGGCTTTTGCGGACAGATCGAACATGACGTTGCACACGCGTCTCCATTCGGGCCTCAAACCTTATCAATGCACGCTCTGTTCCAAGGCATTCACCAAGAAACATCATCTGAAGACACACTTGAATTATCACACCGGTACAAAACCATATTCTTGTCCAAATTGTTCACTGCGATTTTCCCAGAGCAGCAACATGAGGACACACTATAAAAAGTGCTGTTCCATGGCTGGAATCGAAGGATTCGATCGCCACGATCCCACAACCGGAAATGAGCAGAATAATCAAGGTCCAGGAGCTCAACCGACCAATTCTTTGCTCGTAGCCTCAGGCGTCGAAACTCCTTCGGTTGGAGGCCCAACGAACGCCCTAACTCCACCCAATTCTGACCAAGAATCCAGCATCCAAACCCCGACGAAAATTAACCAAGCAATTGCATTGCGTTCGACTTGCCGTCCTCGTAAAATAGACATCAATGTCGTTCTTGACACGTGA
Protein Sequence: MMGEVIRVSGRAPDVGDLLREAMVSQRFADVALCCSGGQRFLAHRLVLSAASPYLQDVFLAHGKAAGSSEPITIILAEVEGPELSAILGFVYTGSATIPKSRLEAFTRAAETLHVRIPKFGSPVRLDVGNYEILSSSCNRDGDCKFDCVKVEETARLKDARYLRCEQYPSWEGWLNPSDWHYHRECTRRVFQPEDWIPRRKENGATLQRQREAEAPSFSEDVEATSRKHLPRENFDNSFCIERTFEKSVDGFERRKSPWIEGDSSVSNPSSLFLDPSKSIPEIRKEPENYEFPVQAHPGLEVFVAAPSKLVDSFSATGNYSSRTSLESCRVYEDRIEENPRENGDFEPRTNLKFDNHDYENSSPFSSKLPISPSSNLQSSTEILPETTVSSNIPLQFTTNLTNLTIPSKNSNFCSDNCCTWRTPKRHVANRVPASPWCQLARPAHHSPKTRPILPRNPNENVEPPVHPDWNGAVVPNETRSRGFSPSRVTYVDNNQIGAGSLHENLEGNGSSEGTGAIYGFQVPKISRGFSPNVEECADYSKQPRSQEEKFYDEKSYEKSSTFPAPGNFSTEHFPARTIAHDRSIEKPSALVDILQDQSRPQQSNEASNIILNHEQSRVRISQHAIPPQANPNKQIINDPPSCNLQTSPRLELSHPISRLCDSVRNIDDSVSREKIFIDKDTPESSSLGIQPIESKLEGSLDFRSKTNLSVSHAIIQSDDNNNEPGINDPVPDISTNPDFRLNEDVHDNVTQDEATGNGEDHRCEQCGKTFVTRASLKVHGRTHSGEKPFRCTDCGKEFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYGCSECGKSFNQRVAYNMHVRIHTGVKPHQCDQCGKAFSRKMLLKQHLRTHSGERPYQCQICHKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCSLRFSQSSNMRTHYKKCCSMAGIEGFDRHDPTTGNEQNNQGPGAQPTNSLLVASGVETPSVGGPTNALTPPNSDQESSIQTPTKINQAIALRSTCRPRKIDINVVLDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00829662;
90% Identity: iTF_00439643;
80% Identity: iTF_00439643;