Basic Information

Insect: Diachasma alloeum
Gene Symbol: ham
Assembly: GCA_001412515.3
Location: NW:850684-919849[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1.4 1e+02 3.1 2.0 2 10 283 291 282 305 0.89

2 9 0.56 42 4.3 0.1 1 23 312 335 312 335 0.91

3 9 1.2e-05 0.00088 19.0 0.0 1 23 341 368 341 368 0.96

4 9 3.4e-06 0.00026 20.7 2.6 1 23 374 396 374 396 0.95

5 9 3.3e-05 0.0025 17.6 5.1 1 23 402 424 402 424 0.98

6 9 0.0021 0.16 11.9 0.5 2 21 432 451 431 452 0.94

7 9 4.9e-09 3.7e-07 29.6 1.2 1 23 830 852 830 852 0.99

8 9 6.5e-07 5e-05 23.0 3.2 1 23 858 881 858 881 0.97

9 9 7.3e-06 0.00055 19.7 3.4 1 23 887 909 887 909 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1.4	1e+02	3.1	2.0	2	10	283	291	282	305	0.89
2	9	0.56	42	4.3	0.1	1	23	312	335	312	335	0.91
3	9	1.2e-05	0.00088	19.0	0.0	1	23	341	368	341	368	0.96
4	9	3.4e-06	0.00026	20.7	2.6	1	23	374	396	374	396	0.95
5	9	3.3e-05	0.0025	17.6	5.1	1	23	402	424	402	424	0.98
6	9	0.0021	0.16	11.9	0.5	2	21	432	451	431	452	0.94
7	9	4.9e-09	3.7e-07	29.6	1.2	1	23	830	852	830	852	0.99
8	9	6.5e-07	5e-05	23.0	3.2	1	23	858	881	858	881	0.97
9	9	7.3e-06	0.00055	19.7	3.4	1	23	887	909	887	909	0.99

Sequence Information

Coding Sequence: ATGAGTTGTCTCGATCTCAGCGTTAGGGAGACATGCCACAGTGGTAGCAGTGACGAGGGTGAAACAGCAATCACTGGTGCCGCAGGGGGCACTGGTGAGGTCACAGAGGGACCAGAAATGGAGGAGTGCGTGAGGTCCTCGAGTGGCAACAGCAACTCATCGAATTATCACCTGAGGCAAACATCGACCTTCGATTTTCCTCAGATCATGGATATGCAGTCGCACGACAGAAATGAAGACACCAAGTCCAGGGATTTCTGGGAGCGTATGGCGGATCAGAAGGACTTCAGGTCGAGGGACAGTTACATCAGTGATTATCAAGACACAATAAAGGAAGAGCCGAAGGACCCAGAAGACCATAAAGACCCCTCAACAGAGTGGCTGTCACCAGTGCCAGAGGTTGAGGTTGGAAGCACTCTGAATGAGGGACCCCATGTTCGAGCGAGGAAGGATATCCCTAGGGGCGCCAGGTTCGGCCCCTTCCTGGGAAAGTGGACCATTAACCCGTACAACCCTAGATACGCGTGGGAGGTTCGACACTCGGGTAGTGGAGTCCGAGGATGGTTAGACGCCTCTCGCGAAGCTAGCAATTGGCTCAAGTACATCAGGAGCACCGGCAATCCTCAAGCTGTCAATATGCGCCACGTTCTGATTGGTGGAGAGATTGTCTACGAAGCCGTAAGAGACATCTCCACTGGCGAGGAGCTCCTGATGGGTCCAAGAGAGCCCCTCCAACTCCAGGACATGCGAGAGAACACGACTGAGGACAGGAGCGATCGCGAGACCGAATCACAACACAGTGGTACGGCTGACGAAGAGAGGGAGGAGGACAAGGAGGGGGAAATTCGTTGTCCAGTCTGCGACAAACCCTTTCAAGAGATTGACGTATTGGATTGTCACCTGGTGACCTGCCACCGCTACCCCTTGGACCAGCACCGCTGCGACAGCTGTTCCCGAGGATTCGCCTGGCGTCCCCTGCTAGTCCGTCACCGAGCCCTCATCCACGGAGACCTCCGGAAGTACCCCTGCGAGAACTGTCCAAAGGCGCCTCCCCAGGTATTCACGGACGCCTCCAACCTCCAGCGCCACATCCGCACAAATCACGTGGGCGCTCGCAGTCACGCATGCACCGAGTGTGGAAAAACCTTCGCAACGTCATCAGGGCTGAAACAGCATACCCACATTCACAGCAGTGTCAAGCCCTTCACATGTGAGGTGTGCTTCAAAGCCTACACCCAATTCTCAAATCTCTGCCGTCACAAACGCATGCACTCCCTCTGCCGAATGCAAATAACTTGCGCCAAATGTGGACAATCCTTCAACACCGGTACCTCTTTATCAAAGCATAAACGTTTCTGCTACTCGACAAATCCATCCCGCTGTGGTAATCCTCATCCCCCACCACCACCGCCACCACCACAATCAGGCGTCATGTCTCAACTGCCATCATCAGGTGGTGATCCATTCCTGGTGTATCCACGTCCGCCAGTCTCCCTACCAGGAGGTTTTCCCCTCTACCCACCAGCTCTGATGGCCCCCTACCACGGCATCTTCCCCAATACCCCCAACTTCCTGAACACCCCCCTCCTCTTCCCAAAGATCCCCGAGGATCCAAAGCGAAATCAAAGCGAGAGCCCAAAGAAGGAGAGATTCACACCACCGAGAATCCTCCCAACGAACAAAGTCTCACCATCAGCTGGTGAAGAAGCCACATCGACATTCAGACCATCACCAGCACGACCGAGTGTTCAACCCACCCCAGACAGCGATGATGAAGTCAAGAAACGTGATACACTAGTGGAAAAAATGGAGACTGAGTCATCATCGTCGTCTGAATCCACTGATCAACCACTTGATCTACGAGTTATGAAGAAGACTGAGACACCTGGGGAGTCAAGAATTGCCGAGAGTCGAACGCCATCACCAGCACCAGTGCCGAGGAGCATTACTCCCGAGGTGAAGACGTCTGTCAATGACGAGGAGAAGGAGCAAAAGAGAAATATGGATGCCAGAATAATGAGCGAAATGAGTAAATTGAGCGAAATAAGCAAATTGAGCGAAATGAGCAAaatgagcgaagcgagcaaaaCGAGCAAAATGGGTAAAAATCGTGATACACGCGATTTTCATGAATCCCCATCGTCCCCAGTGCCCATGACTCATCCACAAGAGCAACAACTTCCAAATACACCCCCTCACATCTCCTATCCACGTCCCATTCATCCCATGTTCATCGAGGCAATGTACAGAAATCCAGGAACATTTCCGGGTTTTCATTCAGCTCCACCATCAGCTCCCGATTCTCGTCTTCTGCCGCCATTGCCCCACTTTGGACCCACCCGGGGTCTTCCATTTTTGGGAAATCTCATGAATGGTCTCAATAGACCGGGTTTCGATATGCTGGCAAGACCacccatgaattttcctgggGTCAAGCCTTTTCAAGAGACTGTGATGCATCATCCCCTGGGTAAAATCAAGGACAGGTACTCCTGCAAATTTTGTGGCAAAGTATTTCCAAGGTCAGCTAATCTCACGAGACATCTGAGAACGCATACCGGTGAGCAGCCGTACAAGTGTAAACACTGCGAGAGATCCTTCAGCATCTCCAGCAATCTTCAGCGTCATGTCAGGAACATTCATGACAAGCAGAGGCCCTTCAAGTGTCCACTGTGCGAGAGGTGCTTTGGACAGCAGACCAATCTCGACAGACATCTCAAGAAGCATGAGGCTGATGACGGAAGTGTCGTTGTTTCCGTTGCTGATTCACCAGGAAGTAGTAATGAGAACGATCGGGAGGAGACATACTTCGATGAAATCAGGTCGTTCATGGGAAAGGTCACGTATGCTGGGGATAATTATGGAATTGGTCATCCCGAGTTTATCACTGGGAAGAGGGGGGAGTATGAGTATGATGAGTACAGCGAGGAGAGGGTCAGCCCCATTGATGAGGGGGGCTTGAGCCCGGAGGGGGGCAGGAAGGAGATCAGGGACGGGTTCGAGATGGGCTGCAGGGACAAGGGGGAGATGATTAATAATAACACTGCTGAACCAGTTATTGAGATTTCTACATAG
Protein Sequence: MSCLDLSVRETCHSGSSDEGETAITGAAGGTGEVTEGPEMEECVRSSSGNSNSSNYHLRQTSTFDFPQIMDMQSHDRNEDTKSRDFWERMADQKDFRSRDSYISDYQDTIKEEPKDPEDHKDPSTEWLSPVPEVEVGSTLNEGPHVRARKDIPRGARFGPFLGKWTINPYNPRYAWEVRHSGSGVRGWLDASREASNWLKYIRSTGNPQAVNMRHVLIGGEIVYEAVRDISTGEELLMGPREPLQLQDMRENTTEDRSDRETESQHSGTADEEREEDKEGEIRCPVCDKPFQEIDVLDCHLVTCHRYPLDQHRCDSCSRGFAWRPLLVRHRALIHGDLRKYPCENCPKAPPQVFTDASNLQRHIRTNHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFTCEVCFKAYTQFSNLCRHKRMHSLCRMQITCAKCGQSFNTGTSLSKHKRFCYSTNPSRCGNPHPPPPPPPPQSGVMSQLPSSGGDPFLVYPRPPVSLPGGFPLYPPALMAPYHGIFPNTPNFLNTPLLFPKIPEDPKRNQSESPKKERFTPPRILPTNKVSPSAGEEATSTFRPSPARPSVQPTPDSDDEVKKRDTLVEKMETESSSSSESTDQPLDLRVMKKTETPGESRIAESRTPSPAPVPRSITPEVKTSVNDEEKEQKRNMDARIMSEMSKLSEISKLSEMSKMSEASKTSKMGKNRDTRDFHESPSSPVPMTHPQEQQLPNTPPHISYPRPIHPMFIEAMYRNPGTFPGFHSAPPSAPDSRLLPPLPHFGPTRGLPFLGNLMNGLNRPGFDMLARPPMNFPGVKPFQETVMHHPLGKIKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKHCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSVVVSVADSPGSSNENDREETYFDEIRSFMGKVTYAGDNYGIGHPEFITGKRGEYEYDEYSEERVSPIDEGGLSPEGGRKEIRDGFEMGCRDKGEMINNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00438952;
90% Identity: iTF_00438952;
80% Identity: -