Basic Information

Gene Symbol
-
Assembly
GCA_012273795.1
Location
CM022547.1:111336-113137[-]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 7.1e-20 3.8e-17 63.2 0.0 3 84 6 81 3 84 0.84
2 2 4.2 2.3e+03 -0.2 0.0 3 39 86 115 84 135 0.48

Sequence Information

Coding Sequence
ATGCCTTGTTATGCAATTATAACTTGTAAGACAAAAAGTCAGACCTCAAGTATAGAGCGAGGAGGTATATCTTTCCATAGgtTTCCTAAAGAACCTAACGCCAGGGAACAATGGATTGACGTGACAGGTAGAGGAAACTGGATGCCGACAAAGACGAGTACTATTTGCTCTAAACATTTTACTGAAAAtgattttatcataaaaaaatcaggtTATAGGTACTTAAAACCAGGGGCAATCCCAAGAGAAAAAATTGTACAGATATGTTCCAGTTCTTTGgatttACAAGCACAGGCGTCAACTTCAGTTTTGTTAACACCAAAAAAAGATAAatctttaaaaagaaaagataCTAGAgacgAAGATATATCTGTtctcaaaaatttaaatgttaaggTATGTTATATATTGGATGTGGGCTTATAA
Protein Sequence
MPCYAIITCKTKSQTSSIERGGISFHRFPKEPNAREQWIDVTGRGNWMPTKTSTICSKHFTENDFIIKKSGYRYLKPGAIPREKIVQICSSSLDLQAQASTSVLLTPKKDKSLKRKDTRDEDISVLKNLNVKVCYILDVGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00433209;
90% Identity
iTF_00357570;
80% Identity
-