Basic Information

Gene Symbol
salm
Assembly
GCA_963921185.1
Location
OY992530.1:304629509-304634372[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.00026 0.072 15.6 3.3 1 23 25 47 25 47 0.95
2 16 2e-07 5.5e-05 25.4 1.1 1 23 53 75 53 75 0.98
3 16 1.8e-05 0.0049 19.3 0.8 1 23 81 104 81 104 0.98
4 16 0.0015 0.4 13.3 1.1 1 23 114 137 114 137 0.95
5 16 6.4e-07 0.00017 23.8 1.6 3 23 234 254 232 254 0.97
6 16 2.2e-07 6.2e-05 25.3 1.2 1 23 260 282 260 282 0.99
7 16 0.0011 0.3 13.7 0.5 1 23 293 317 293 317 0.96
8 16 0.0016 0.45 13.1 1.3 1 20 323 342 323 344 0.93
9 16 0.27 73 6.2 3.4 1 23 382 404 382 404 0.97
10 16 5.4e-07 0.00015 24.1 1.4 1 23 410 432 410 432 0.99
11 16 7e-05 0.019 17.4 1.5 1 23 438 460 438 460 0.96
12 16 2.4e-05 0.0067 18.9 2.3 1 23 466 488 466 488 0.97
13 16 5e-07 0.00014 24.2 1.4 2 23 590 611 589 611 0.98
14 16 2.9e-05 0.0079 18.6 0.8 1 23 617 639 617 639 0.99
15 16 3.9e-05 0.011 18.2 0.4 3 23 648 668 646 668 0.98
16 16 0.0019 0.53 12.9 4.1 1 23 674 696 674 697 0.95

Sequence Information

Coding Sequence
ATGGACTGGCTTATTGCAAATGACGCAAATAACACAAAATGTCGAAGCAAATCGAAGAAAGTCAATGGTAAATATCGGTGTCAATATTGTGAGAAGAAGTTTGCCAAACCTTGTTTGCTGAAACGGCATGAAGTTTCTCATACGGGAGCTAAACCATTCCAATGTACCCAGTGCGATCAGGGATTTACACAAAAATCTTCCCTTGAAAGGCATATGCTTCTACATCAGGGTGTAAAAGATTTCAAATGTCCCATGTGCAGCTATAGCTCCTCTCAAAAGAACAACTTGATTATTCACATTCAACGTACTCATCCAACTAACGCTACTGTCGAAAATATGTTTGCTTGTGAGTTTTGTCCGTGTGTGTTTACAAAATTAAGCAGTGTCAATCGTCATCGAGCAATGGTGCATCCAGAAAAGGAGAACTCAACCGGCCAAGATGGGTTCAATGCCAACGACGAGGATGAAGACGATGATAATGTGACCGTTGCAAGAGTTATGGAAcagttaaaaagttttcaagaaTCCATGGGAATTATGGATATGAAACCACCCGCATTGGAACTCTCCCTTATGAAACCACCATCACCTGGGCCAATAGTCAATACAGTAACCATTGTTGATACAATCAATCCAAATAAAGAGAAGACGTTTAAGAAAGTCAAAGAAATCATCTACAAAGGACAACGCACAATTGCTTGTGTTTATTGTGATAAGCCATTTAAGAGGCAGTATGATCTTTTGAGACACCATCGAACTCACACCAAAGAAAAGCCATTCCAATGTAATATTTGCACTAAAAACTTTTCCTCCAGTAGCGGCCTTAAAATACATCTCAACACTCATACCTCATCTGCAGCAAAGCCAGCTAGAGCTTATGAATGTGTGGCAGATGAGTGTCATAAACGGTTTGCATCATTGCGTGCATTAGATATTCACACAAAAACCCACTCAAATTCCATATCGTACATCTGTCCCATTTGTTCGAAAATCTTCACATCCAAAGCCGGGTTTTCCTCGCACAAACATCATACGAAAGATCAAGAACTCGATAGTATTCGTGAGTTTTTAAAGTCTCCtgtaaaaattgaaacaaataagGCCGAAGAAGCTTACAAGGCCGAAGAGTATATGAAAAGAAGCCACCAGTGTTTTGTCTGTggcttgaaaatgcaaaaattatcCCATCTTCGGCAGCATGAAGCTACCCATACGGGAGTGAAACCATTTCAATGTGAAATTTGCTTTAGGTCCTACACAACACAAAGTTCTCTCAATCTTCATATGAAAATCCATACAGCTGAGAAAACCCACATCTGCCAAGTGTGCAATGCGAAGTTCTTCACACAATCCTTGCTCCTACGACACATGATCTCACACAATAATGAACGAAACTTTGCCTGTCCTTACTGCGATGAACGCTTTAAAACGAACGACAATTGCAAGAATCATATTTTAACTCACGCCCGGAGTTTATTGGCAAGTCCTGATCCTCCACCCCCTCCACCAGATGAATATGTCATCGATGTTGATGAAATTGCCGAAAAACCCTCTGTAAATTCCATGATAAAGCCATATATTGCCGTAGTTGAGAGTCCCGAGAAGAATCTCTCACCAAAGTTCCTTCAActtgaattggtcagaaaatgcaaaaaacataAGCACAAGAATTTGACTATCGAAACACTAACAACACCAAAGAAAACATCATCCACGTCCAAGAAATCCCTAGAACGATCGGTCAGACAGATAAGTCAAACTGGAAACAAATGCACTGAATGCGGgaagattttcttcaaagccaGTGATTTCCAACGTCACATTCGAACTCATACAAAAGAAAAGCCATATCAGTGCAGTATCTGTTCGAGGCAATTTGCATTAATGTCCACCTTGGTGAATCATATGAAGACACATGACGCACAGAGAGAGACATTCGGCTGTCAGGTGTGTGGCAAGAAGTATTCATCGCAGAAAGTTCTGACAGTGCATTTACGAATTCATACAGGTGAGAGACCTTTTCAATGTGGTGCATGTAAAAAGACTTTTCGAACTTCAGGACATAAGATTTCACATATTAAGGCACACcataaaaagagaaaatag
Protein Sequence
MDWLIANDANNTKCRSKSKKVNGKYRCQYCEKKFAKPCLLKRHEVSHTGAKPFQCTQCDQGFTQKSSLERHMLLHQGVKDFKCPMCSYSSSQKNNLIIHIQRTHPTNATVENMFACEFCPCVFTKLSSVNRHRAMVHPEKENSTGQDGFNANDEDEDDDNVTVARVMEQLKSFQESMGIMDMKPPALELSLMKPPSPGPIVNTVTIVDTINPNKEKTFKKVKEIIYKGQRTIACVYCDKPFKRQYDLLRHHRTHTKEKPFQCNICTKNFSSSSGLKIHLNTHTSSAAKPARAYECVADECHKRFASLRALDIHTKTHSNSISYICPICSKIFTSKAGFSSHKHHTKDQELDSIREFLKSPVKIETNKAEEAYKAEEYMKRSHQCFVCGLKMQKLSHLRQHEATHTGVKPFQCEICFRSYTTQSSLNLHMKIHTAEKTHICQVCNAKFFTQSLLLRHMISHNNERNFACPYCDERFKTNDNCKNHILTHARSLLASPDPPPPPPDEYVIDVDEIAEKPSVNSMIKPYIAVVESPEKNLSPKFLQLELVRKCKKHKHKNLTIETLTTPKKTSSTSKKSLERSVRQISQTGNKCTECGKIFFKASDFQRHIRTHTKEKPYQCSICSRQFALMSTLVNHMKTHDAQRETFGCQVCGKKYSSQKVLTVHLRIHTGERPFQCGACKKTFRTSGHKISHIKAHHKKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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