Basic Information

Gene Symbol
-
Assembly
GCA_963555695.1
Location
OY743166.1:8386009-8399096[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.12 19 7.6 0.5 1 23 235 257 235 257 0.95
2 15 0.003 0.48 12.7 0.4 2 23 329 351 328 351 0.94
3 15 0.0027 0.43 12.8 1.8 2 23 357 379 356 379 0.94
4 15 0.0072 1.1 11.5 1.0 1 23 384 407 384 407 0.97
5 15 0.35 55 6.2 0.1 2 23 410 432 409 432 0.92
6 15 0.055 8.7 8.7 2.2 2 21 439 458 438 459 0.93
7 15 0.0021 0.34 13.1 0.5 1 23 518 541 518 541 0.95
8 15 0.029 4.5 9.6 0.2 3 23 570 591 568 591 0.92
9 15 0.017 2.6 10.3 0.7 2 23 614 637 613 637 0.96
10 15 0.0017 0.27 13.5 1.5 3 20 644 661 642 665 0.90
11 15 0.43 68 5.9 0.3 1 23 670 693 670 693 0.96
12 15 0.00012 0.019 17.0 0.2 2 23 699 721 699 721 0.96
13 15 7.3e-05 0.012 17.7 4.8 1 23 725 748 725 748 0.97
14 15 0.0028 0.45 12.8 0.9 2 23 755 776 754 776 0.96
15 15 0.055 8.7 8.7 1.2 1 23 782 805 782 805 0.93

Sequence Information

Coding Sequence
ATGGAGTTCGACGAGATAGTGGTGAAGGAGAGCCCCGGGCTTTGCCGGTGCTGTCTCTCTGAAGGATGCTACAAGGATTTGGGCACTGAATATACCTGGATGAATGAAACAGAGGTTTATGCTGATATGCTGCTTGAATGCTTTGATATTAGCATAACACAGCACAATGAAGGTCCGAATGGTCCAAACCGACTTATCTGTGAGGTCTGCATCACTCGATTGCGAGACGCTTGCAACTTCAAGAAACAAGTAATGGACTCGGAGAAGAAATTTATTGATATGATGGGCAGGGGAGAATTTAGACCTAAGATGCTTATCTACCAGGCCCAGCTGAAGTGTGAGGGGCCAGCTGCGGCGGAGCAgcctgatgatgatgacgttgaATATCTTGAAGATGATCTTGATTTTACTGATGCCAACCTTAAAGACGAATTAACACAGCCATCGGGATCAGACGTCACGGCAGCCGCGTTACCCGCTAAAGGCAAACGCGGTCGTCCTCGCAAGAACACACCAGTGAAGCCCGAAAAGAGGACCAAAGTGGCCAAAGTAGACGAAAAGGCCAAGACATCGAAAGGTGTAGCTAAAGGTAAAAAACCGAGGAAAGACAAGGGCACTGAGTCTTCCTCGATGAAAAGGCGACGGAACCTACAAATTATTTTCAACCACACATCTATTATTCCTTTTAAATGGCGTGGGAAGTACTTGTGTTTCTATTGTAGCAAAAATATCGCCGAGTATGCAGAGTTAAGAAAACATACGAAAGCACATGGCAACTGTTCCATAAATGACCATTCGCTTAAAGTCTTAAAAGGAGGACAGAACATGGAAATTAAAGTAGACATATCATTGATTACTTGCGAAGTGTGTGCGGTGACATTACCGTCTTTCGATGAAATCGTCACTCATTTGTTCGACAAACATGAACTTGAATACGATAAAGGAGTAGAAATGGCCATAGAACAGTATAAACTTGCTGATCTCAGTTGCACGGGATGCGATGAGAAGTTCACGTATTTCGGCTACCTAGTCTCCCACGTCAATAATACCCACCCCAAAAACTGCCTCATTTGCGATAACTGCaaccaaaaattcaacaaaaagaGAGATCTATTTTCTCACGTGAAAAATTACCATCGAGAGGGAGGGTACCAATGCGAAATGTGCCCCCAAATCTTCAACTCATTAAATATACTAAGGAAACACCGAAAGAATAGGCATTTGACTCGATGCAACATTTGCAATTTGAAACTGCCGTCAGCTGCTTTGAGACAAAAACATATCGATTTAGAACATCCGGACGACGGGTCTTTGCAGTGCGATACCTGTTTCAAAGAGTTCCACACGAAACAAGGGCTCAAGATGCATTCAAGGAAATGTAAAGGAGAGGAGATTTTCGGAATCGCCATCAAAGAAGAAAACGTTGCCATGGACTTAGATCTAAACTACGAGGATCAATCCAAAAAACCTTGCGTCAAACAAATCAGAGAGAATATAGTTATAGTCATAAACATGTCTACTGCGAtaccttttaatttttataagaataaGTTTAACTGCTTTTATTGCTCCAAAGATTTTGCCGATTCCGATTTGATGAGGGAACACACGATTATGGAACATCCTGTGTGCGATGTTAAAGAAAAGTGTATTAGAAAATGTAGGGAGTCCGCCGCATGCGTCAAAATCGATATTTCTTCACTCGCTTGCAAAGTCTGCTTTGAGTCATTGACTGATTTGGATCATTTAATCGATCACTTAATCGCGAAACACGATGCGAAATACGACAAATCAATAACAACGTGCTTACAACCCTACAGGCTGATTAAAGACAACATGGTATGCCCACACTGTCCCAGCGAGGTATTCCGCTTCTTCGGAACGCTTCTTAAACACATGAATATCAAGCATACCAACAACAATATCATTTGCGTTTATTGCGGACATACATTCCGTAGGGATCAAAACCTAAGAGTTCACATTTGGCGCCATCACAGAGCCGGGAGGTTTCAATGTACCATTTGTGCTGCTGAGTGCAACATACCGTCTCGTCTGTACATGCACATGGCTCGAGCACACGGCGTTAAAGCTGCTAAATGTCCCAAATGCCCCGAATCTTTCGCTACGCAATATGAAAGGCAGAAACATTTGATCATCGCCCACAACACTGGCCACAAATGCTCTTACTGTGGAAAACTCTTTACAAGAAACTCGTTTATGAGTAACCATATAAGGAGAACGCATATGAAAGAGAAGAGCATAGAATGTTCTGTTTGCTATACGAAATTCTTTAACACTGTTCTGTTGAAAAGGCATATGGTGAAGCATAGCGGGCAGAAGAAGTATAGTTGTGATGTGTGTGGGGAACGGTTCTACTGGCGCAAAACTATGAAGACGCATAGAGATAGGTTGCATAGTAAACAGCTTTATCCTGCGCCTATGTAA
Protein Sequence
MEFDEIVVKESPGLCRCCLSEGCYKDLGTEYTWMNETEVYADMLLECFDISITQHNEGPNGPNRLICEVCITRLRDACNFKKQVMDSEKKFIDMMGRGEFRPKMLIYQAQLKCEGPAAAEQPDDDDVEYLEDDLDFTDANLKDELTQPSGSDVTAAALPAKGKRGRPRKNTPVKPEKRTKVAKVDEKAKTSKGVAKGKKPRKDKGTESSSMKRRRNLQIIFNHTSIIPFKWRGKYLCFYCSKNIAEYAELRKHTKAHGNCSINDHSLKVLKGGQNMEIKVDISLITCEVCAVTLPSFDEIVTHLFDKHELEYDKGVEMAIEQYKLADLSCTGCDEKFTYFGYLVSHVNNTHPKNCLICDNCNQKFNKKRDLFSHVKNYHREGGYQCEMCPQIFNSLNILRKHRKNRHLTRCNICNLKLPSAALRQKHIDLEHPDDGSLQCDTCFKEFHTKQGLKMHSRKCKGEEIFGIAIKEENVAMDLDLNYEDQSKKPCVKQIRENIVIVINMSTAIPFNFYKNKFNCFYCSKDFADSDLMREHTIMEHPVCDVKEKCIRKCRESAACVKIDISSLACKVCFESLTDLDHLIDHLIAKHDAKYDKSITTCLQPYRLIKDNMVCPHCPSEVFRFFGTLLKHMNIKHTNNNIICVYCGHTFRRDQNLRVHIWRHHRAGRFQCTICAAECNIPSRLYMHMARAHGVKAAKCPKCPESFATQYERQKHLIIAHNTGHKCSYCGKLFTRNSFMSNHIRRTHMKEKSIECSVCYTKFFNTVLLKRHMVKHSGQKKYSCDVCGERFYWRKTMKTHRDRLHSKQLYPAPM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00071771;
90% Identity
iTF_00375619;
80% Identity
-