Basic Information

Insect: Dascillus cervinus
Gene Symbol: ZFX_1
Assembly: GCA_949768715.1
Location: OX458320.1:31354943-31358116[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.04 2.6 9.7 0.9 1 23 88 111 88 111 0.89

2 14 0.012 0.79 11.4 0.0 3 23 119 139 117 139 0.93

3 14 0.00027 0.018 16.6 1.4 1 23 172 195 172 195 0.97

4 14 1.3e-05 0.00083 20.8 2.3 1 23 200 223 200 223 0.96

5 14 0.01 0.67 11.6 1.0 1 20 232 251 232 253 0.93

6 14 1.6e-06 0.00011 23.6 0.7 3 23 282 303 280 303 0.95

7 14 8.6e-06 0.00057 21.3 0.4 1 23 309 331 309 331 0.98

8 14 0.00036 0.024 16.2 1.8 1 23 337 359 337 359 0.96

9 14 1.5e-05 0.001 20.5 1.4 1 20 365 384 365 385 0.96

10 14 3.9e-06 0.00025 22.4 0.2 1 23 396 418 396 418 0.99

11 14 0.00063 0.042 15.4 3.3 1 23 424 446 424 446 0.97

12 14 0.002 0.13 13.8 1.2 1 23 452 475 452 475 0.96

13 14 7.4e-05 0.0049 18.4 3.4 1 23 489 511 489 511 0.98

14 14 0.00024 0.016 16.8 1.4 1 23 517 540 517 540 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.04	2.6	9.7	0.9	1	23	88	111	88	111	0.89
2	14	0.012	0.79	11.4	0.0	3	23	119	139	117	139	0.93
3	14	0.00027	0.018	16.6	1.4	1	23	172	195	172	195	0.97
4	14	1.3e-05	0.00083	20.8	2.3	1	23	200	223	200	223	0.96
5	14	0.01	0.67	11.6	1.0	1	20	232	251	232	253	0.93
6	14	1.6e-06	0.00011	23.6	0.7	3	23	282	303	280	303	0.95
7	14	8.6e-06	0.00057	21.3	0.4	1	23	309	331	309	331	0.98
8	14	0.00036	0.024	16.2	1.8	1	23	337	359	337	359	0.96
9	14	1.5e-05	0.001	20.5	1.4	1	20	365	384	365	385	0.96
10	14	3.9e-06	0.00025	22.4	0.2	1	23	396	418	396	418	0.99
11	14	0.00063	0.042	15.4	3.3	1	23	424	446	424	446	0.97
12	14	0.002	0.13	13.8	1.2	1	23	452	475	452	475	0.96
13	14	7.4e-05	0.0049	18.4	3.4	1	23	489	511	489	511	0.98
14	14	0.00024	0.016	16.8	1.4	1	23	517	540	517	540	0.95

Sequence Information

Coding Sequence: ATGCCAAATTTAAGCGACTGCTGCAGCGTGTGTTTAAGCAACGCTCAGGAACTAATCAAAACCAGCGAAAAAGACCCCCAGGATGTGAAATGGACGTTTAAGCTTGCCAAATTCGTCCCAGAAATAGACTGGTTGGACGATTATTTCATTTGCCAACCCTGCACCACACAACTAGAATCGGCTTGGAGCTTCCGAGAGCTCTGTCTCCAATCGCACACAATCGAAACTAAAGAAAATGTCCCGCTCGACATCCCCGAATGCCACATTTGCAGCCTCTGTGACGAGAAATTCCCCTCGAGGAAGGATTTAGGGCTACATAATGAGTCCAAGCACGGCCTGGAACGTCCTTACGGCTGCGCGATCTGCGGCGAGAGTTTTAAGACGGATTCAGAACTCGACGGGCATGAAACCGTCCACAAGTTTCACTGTTACGACTGCAACACGTCTCACAGCTCGGCCGTGATTTTAAAAACGCACAAGATCTTCAAGCACAGCGATAGGAGCGAATGGAAGCACGAATGTCCCCAATGTGGGGTCAAACTGCCGCTGAAGTCTCACCTGGAGAGGCACATTCAGAGGCAGCACGAAAAGGGGCCCTTCATCTGCTTCCACTGCGACAAAACGTTCACTAATAAGGTCTTCCTCGCCGCCCACATCCGTTTGAAACACGGCAAAGACGACGAGAAGAAGAGGTACAAATGCGTGAAGTGTTCCAAGACGTACGCCACTGAGAAGTCGATGAAAACTCACTCGTTGACTTGCGTGAGCGCGAGCGAGGCTGTGGAAGTCGAAAGGGTCACCAGGAGGAGGGTCAAGAAGGAGTTGGAGGAATCGGGGACGAACTGCGATGTCTGTGGGACATCCTTCTCGACCAAGTATCTGTTGAGGAGGCACGTGCGCAACGTACACGCCACTGAAAAGAAATTCAAGTGCGAGATATGCGGGCAGAAATTTGCCAGCCCTGTATATCTGTCTGCCCATAAAAGGTACCATTCTGGAGATAGGCCGCACATTTGTTCGTTCTGTGGCAAAGGTTACATCACAGCCAGCGACCTCTACCACCACGAGAAGATCCACGCGAACAAACGGGCCTACAAGTGCGACAAGTGCCCCAAAGCCTTCAACACCTCCTCGGACCTCCACAAGCACAAGATCTGCGTCCACATGGACAGGAGCGAATGGAAGTACGTCTGTGGGTACTGCGGGCGCCGGTTCCCCCTCAAAACGAACCTGGACGCCCACATCAAGACCCACACCGGCGAGAAGAATTTCGCGTGCCACTTGTGCGACCGCAAGTGCATAAATCGTTCGGTTTTGCAAAGACACATCGAGTCGCATTCGAACGTGCGTCTGTTTAAATGCAACGTCTGCAACCAGGACTACAAGTACCAGAAGTCGCTGGACATACACTTGACCAAGGCCCACGGAATCGGGGACGCAAAGGTGCCCCAGAGAGTCAAGAAGTACTTCTGTCACATCTGTCCCAAGTCCTACTTTGCGAACAACAAGCTGCAGAAGCACATAAGGACTCACACCGGCGAACGGCCGTTTTCGTGTCAGTTGTGCGAGAAACGTTTTATTGATAAGTCTTACGTTAAGCAGCACTTAAAAGCGACCCACAATGTTAGTTTTAGTGACGCCGATTAG
Protein Sequence: MPNLSDCCSVCLSNAQELIKTSEKDPQDVKWTFKLAKFVPEIDWLDDYFICQPCTTQLESAWSFRELCLQSHTIETKENVPLDIPECHICSLCDEKFPSRKDLGLHNESKHGLERPYGCAICGESFKTDSELDGHETVHKFHCYDCNTSHSSAVILKTHKIFKHSDRSEWKHECPQCGVKLPLKSHLERHIQRQHEKGPFICFHCDKTFTNKVFLAAHIRLKHGKDDEKKRYKCVKCSKTYATEKSMKTHSLTCVSASEAVEVERVTRRRVKKELEESGTNCDVCGTSFSTKYLLRRHVRNVHATEKKFKCEICGQKFASPVYLSAHKRYHSGDRPHICSFCGKGYITASDLYHHEKIHANKRAYKCDKCPKAFNTSSDLHKHKICVHMDRSEWKYVCGYCGRRFPLKTNLDAHIKTHTGEKNFACHLCDRKCINRSVLQRHIESHSNVRLFKCNVCNQDYKYQKSLDIHLTKAHGIGDAKVPQRVKKYFCHICPKSYFANNKLQKHIRTHTGERPFSCQLCEKRFIDKSYVKQHLKATHNVSFSDAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -