Dcer008535.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Dascillus cervinus
Gene Symbol
topi
Assembly
GCA_949768715.1
Location
OX458317.1:30074550-30077205[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 4.6e-05 0.003 19.0 4.4 1 22 100 121 100 121 0.96
2 18 0.00019 0.012 17.1 0.1 3 23 129 149 128 149 0.98
3 18 3e-05 0.002 19.6 1.4 1 23 155 177 155 177 0.98
4 18 5.1e-07 3.4e-05 25.1 0.6 1 23 210 232 210 232 0.99
5 18 2.4e-05 0.0016 19.9 4.1 1 23 242 265 242 265 0.98
6 18 0.00024 0.016 16.7 0.4 3 23 273 293 271 293 0.97
7 18 1.9e-05 0.0013 20.2 4.0 1 23 299 321 299 321 0.96
8 18 4.7e-06 0.00031 22.1 1.7 1 23 327 350 327 350 0.97
9 18 0.00039 0.026 16.1 4.1 1 22 487 508 487 508 0.96
10 18 5.2e-06 0.00034 22.0 0.6 1 23 514 536 514 536 0.96
11 18 0.0019 0.13 13.9 2.0 1 23 542 564 542 564 0.98
12 18 0.28 18 7.1 7.5 1 23 569 592 569 592 0.97
13 18 8.9e-07 5.9e-05 24.4 5.1 1 23 597 619 597 619 0.98
14 18 0.00044 0.029 15.9 5.4 1 23 629 652 629 652 0.98
15 18 0.00029 0.019 16.5 0.5 2 23 659 680 659 680 0.97
16 18 0.0024 0.16 13.6 5.0 1 23 686 708 686 708 0.94
17 18 7.2e-06 0.00048 21.5 1.0 1 23 714 737 714 737 0.97
18 18 0.0028 0.19 13.4 2.9 1 23 743 766 743 766 0.92

Sequence Information

Coding Sequence
ATGCAGAAAATacgaacaaaaattttagaagcAGCTTCCCAAAGTAATCCCATTCTTACATTCTCCGCGAAAATTGTTAAAGACATAAAGGGGAATATTAATGAAGAGATAACCAATGAAGAAGTTGATATTTCTAAAGCACGTTCCGATTCtggcaatataaacaaaaaaaaatgccaGCAAGGAAAAGCCAAGGCTGGTGAAATGAAACAGAAAACTAATTTGCAACAgagtgaaattgaaacagTGATCCATGAGAAATTGAAGGAGAAGAAGACCGTTAATAAACCAACACATTTTACTTGCAACAATTGTCAGAAAACTTTTAGAACGAGACACAATTTTCTCAACCATATTCGAAAATATCGCGAAAAGAAACACGGTTGCCCCACTTGTGGTAAAATGTTCGTGGAGAGGGCTCAGCTGAACATTCACACACTTGTGCATAATACTGAAAAGAACTATACTTGCGAAACTTGCTTGAAGAAGTTCAAAACCCCACAAAACTACAAAGCTCATTTAAATGTTCACAaagaattcaaattcaaatgtgAATGTTGTGATAAAAGGTTTCTCACTAAGAACTTGTGTAAAAACCATCACCAGGCCGCTCACTTAGGCCTACTCTATACTTGTAAAATCTGCGGTAAAGCCTTTAAACAAGGCAGTCTTTTAAAAATCCATGAAAGAACTCACGATCCTGGTTACGTTAACATTAAAGCCTTTAAATGTTCCACTTGCGACAAAAGTTTCAGATATCTGAGTACGTTGAATTACCATCAACAGCGACGTCATGGAGACGGTTTAAAACAGATCTGTGAGGTTTGTGGTAAAAGTTTGAGCAATACTGTGACCTACACCCAACATATGAGATTGCATACAGGAGAGAAACCGTTCTGTTGCACATATTGCGGAAAAACTTTTGCTAGCAATTCATATCTTCATTCGCACATTGTGGTCCATACGAAAGCAAGACCGTTTTCATGTAAATTGTGCGATAAACGATTTAGTCAAAAAACGTCTTTAACAATTCATGAGCGATCGATCCATACTGGCGAGCGGCCGTATACATGTGATAATGGTATTAGGAAATTCAGaTTTTCGTCGATATTAACAACAGCAATTCAGAAAATAGGAACAAGAATTTCAAAAGCATCTTTCCAGAGAAACCCCATTCGTAGATTTTCCACGAAAATTGTCAAAGACATAAAGGAGAATATTAAACAAGAGATCACCATTGAAGAAGTTGATGTTTCTCGAGCAATTTCAGAATGCAGCGATataaacgaaaaaatattaaagacGCTCGTGCGAAAGAGAAAATGTCAGGGAAGGAAAGCCAAGACTGGTGAATCGATTGTGCGGAATAATAAACCAATGAAACAGAAAGCTATTGTGCAGCAGAGTGAAACTGGAACAGTTGCCGATGAAGAGTTTGAGGAAAATAAACCAACACATTTTACATGCAACAATTGTTCGAAAACTTTTGTAACGAGACACAAATTCCTCAAGCATATTCGAAAATATCGTGAAAAGAAACACGCCTGCCCCACTTGTGGTAAAATGTTTGTCGAAAGATCTCAGCTCAACACTCACCAATTGGTGCATAGCACTGAAAAGAACTTTACTTGCGAAACCTGCTTGAAGAAGTTTAAAACCCCACAAAGGTACAAAGTTCATTTAAACATTCACaaagaatataaatttaaatgcgAACTTTGTGATAAAAGCTTTCTTACTAATCAACAGTGTCAGCACCATCGCCGAACTACTCACTTGGGCTTACTTCATACTTGTAAAATCTGCGGTAAAACTTTTAAAGACCGCTCTAGTTTCAAAAACCATGAAAGAACTCACGATCCTGATTACGTTGATATTAAAGCCTTTAAATGTCCCACTTGCGACACAAGTTGCAGAACTTTGAGTAAGTTGAAATACCATCAACAGCGACGTCATGGAGACAGTTTAAAACCGGTCTGTGAGGTTTGTGGTAAACGTTTGAGCACTAATTTGAGCTACACCCAACATATGCGATTGCACACAGGAGAGAAACCGTTCTGTTGCACTTATTGCGGAAAAACTTTTGCTAGTAATTCGTGTCTTCGTTTTCACATTGTGGTTCATACGAAAGCAAGACCTTATGCATGTAAATTGTGTGATAAACGATTTAGTCAAAGAACGTCCTTAACAATTCATGAACGATCTATCCATACTGGCGAGCGGCCGTATACATGCGATGTATGTTCGAAAGGCTTCGTTACCAGTACACTATTGAAAACACACTGTAAAAAAGTTCACGGTGTGGTATCGGCAGATATCTTGCCAAAGAAGAAACTGAATTGA
Protein Sequence
MQKIRTKILEAASQSNPILTFSAKIVKDIKGNINEEITNEEVDISKARSDSGNINKKKCQQGKAKAGEMKQKTNLQQSEIETVIHEKLKEKKTVNKPTHFTCNNCQKTFRTRHNFLNHIRKYREKKHGCPTCGKMFVERAQLNIHTLVHNTEKNYTCETCLKKFKTPQNYKAHLNVHKEFKFKCECCDKRFLTKNLCKNHHQAAHLGLLYTCKICGKAFKQGSLLKIHERTHDPGYVNIKAFKCSTCDKSFRYLSTLNYHQQRRHGDGLKQICEVCGKSLSNTVTYTQHMRLHTGEKPFCCTYCGKTFASNSYLHSHIVVHTKARPFSCKLCDKRFSQKTSLTIHERSIHTGERPYTCDNGIRKFRFSSILTTAIQKIGTRISKASFQRNPIRRFSTKIVKDIKENIKQEITIEEVDVSRAISECSDINEKILKTLVRKRKCQGRKAKTGESIVRNNKPMKQKAIVQQSETGTVADEEFEENKPTHFTCNNCSKTFVTRHKFLKHIRKYREKKHACPTCGKMFVERSQLNTHQLVHSTEKNFTCETCLKKFKTPQRYKVHLNIHKEYKFKCELCDKSFLTNQQCQHHRRTTHLGLLHTCKICGKTFKDRSSFKNHERTHDPDYVDIKAFKCPTCDTSCRTLSKLKYHQQRRHGDSLKPVCEVCGKRLSTNLSYTQHMRLHTGEKPFCCTYCGKTFASNSCLRFHIVVHTKARPYACKLCDKRFSQRTSLTIHERSIHTGERPYTCDVCSKGFVTSTLLKTHCKKVHGVVSADILPKKKLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
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80% Identity
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