Basic Information

Gene Symbol
-
Assembly
GCA_010014825.1
Location
JAAAKD010000756.1:23986087-23990079[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 9.6 1.8e+03 1.4 0.4 2 23 358 378 357 378 0.71
2 9 0.19 35 6.8 4.6 2 22 490 510 489 513 0.88
3 9 0.0064 1.2 11.4 8.4 1 23 527 550 527 550 0.97
4 9 0.0089 1.6 11.0 0.8 1 22 555 576 555 579 0.90
5 9 5.5 1e+03 2.2 0.1 2 22 600 622 599 624 0.67
6 9 0.00037 0.068 15.3 0.3 2 22 630 650 629 650 0.95
7 9 1.8e-05 0.0033 19.5 1.0 1 23 706 727 706 727 0.98
8 9 2.4e-06 0.00044 22.2 0.3 2 23 734 756 733 756 0.96
9 9 0.78 1.4e+02 4.9 0.3 2 15 773 786 772 789 0.84

Sequence Information

Coding Sequence
ATGCTCTCGCCTCACGATGACGACGATGACAACCacctttgtattaaatgtaatgcCACTATTATTGGCCTCGATAACTATGTGAAACACAGAAAACAAGGATGCCGTAAAAGAAAAATCGATTCTAAACCAGAACTCGCTTCCATTGATCCATTAGAAGCAACTTATAACCTCGGCGCGGACGTATTCTTTCAATCTTTAGAGTTACAGAGCAGCGTAAAGAGATCACCACTGTCTCGACTGACGCCTCCAACACCGGTTACAAAAAATAGTatcgataaaaaaaactcattgaaTGTAGCGTCAACATCTAGAGATATCCCTAGAATTAGTCCCATTGAAAGTAATTTAAGGGGTGAAGATTGGATTGGCGGTCACAGCTTGAGGATTGGAAGTAACGAAGATAACCAGACTAAATTAATCAACGCTGTTGCCAATATCAGCGGATCTGTTAAAAAAGAACCTCTAAATGCCTATAATATAACTAACTTTAGCGTCTACAAAGAAGACAATGATTCTGAAGAATCGAATGTTTCGGAAGAGGAGGAAGAAGATGAAATTGTCGTTGATGAAGGTTCATGGCCACCTCCACCCAACTACACCGGTGGCAAATGGCGACCGGCGTCACCGGACCAGGAGTGGGATGTCAGAGAAGAACAGGAGCAGGTCGATCGTGACTACGACTATGATGCTCCTCCGCCAGAACATACCAAAGGAAAATGGATCCCAGGGGCCAACGAAAGAACTCAAATCATGCAAACTACTATTCAGACTAAAGGCTCGGTCCAATACTGGTGTGGTCCGTGCAATAGGCGACTAGGCTCTAGAGCTATTTAcgaaaaacatttgaaatcaaACTTGCACATGAGAAAAGTCCTCCCTGAACAAGAGTTGGAATTTACTGGAAGTTTGGTTTCCACTAATAATTCCCTAGTTACACCGCGGTCAGCTGGGGCAGCGATGTTTGTTAGCGCCGTTTACTCATCGCCGacaagaagaagaaataaaaaagagtcAAAAGTTAGCATCAgaatgaataaaaagaaaaggaaacgaACATCATGCTATGTTCAATGCTCCGGTTGTAAGACAAGAgtcaaaagaaatttaatggGGAAACATTTGATATCTCACTACCACTTCAGAAAGGGGACCGTTGTTAAGaactttttatacaaacaattagTTCTCAATAACATAGACGCTATCGTGCACCAAGCCCCTTTCCAATGCAGTCCATGCAAATTTTACACCAACTGGCAAACTAACTTTATGCAACACTGGAACTCAGAAGAACATAGAAGTACCATTTCATCAATAGAAGGTGTATATTGGTGttcattttgtaaatttgaGTCGGAAACGTGTGAGGAGATGTCCGCCCACATAACGAGCACTGAGCATGGGGAAGTGGCTTCAGTTATTAATAGATCCATGCCTATTATAATACGCAAAAAATCTGTTATCAAATGTCATACGTGCCCGATGGTGTTCCGATACAATGTGGAAGTCAAACATCATTGTCGTACAACGGGACACGACTTGCCGTACTCGGCCAGTGACATCTACCAGGAAGTGCATAGATGTCATCActgtaaaaagaaattcaagTTATCCATCTCACTTGTTGCACATTTAAAAAAGAGACACAACGACAGCGTATATTTCTGTCTCCTTTGTTCGAAGACCTTTAACTCAGCTGTAGAAGTCAAGAACCATCGGCAGAGCACAGAGCACAGAGTCAAGCGGTTAGAAGTACTGCGCGAGCGAGGACTGCTCACGAAAGACATATCGAAGAAGTGCCCCTACTGTCCTCAGTATGTCGTCTTAAAGAATACGTTGGAACTGAGGGAGCACATTATAAACGTTCATCCGAGTATTAAGAAAAAatGTCCCAAATGTGGAAAGGAATTCATTTTCTCTCAGGAGGTCTCGCGGCACATTCGCTCCAACGCTTGCAAGCTACACAATCCCGAAGTGCCTCAGTCATCCATTACATGGAAGTGCAGCCAGTGTCTGTTCGTCACGGACTCGCAGGCGGAGTGTTTCTTCCACGAAGTCCTGCACACGGAACCGAGCACCGAGACTACCAAGACgaataaaatcatcaaaaaatacaaatgtcCGCTTTGTCCAAAAACCTTTAGGAAACCATCGCTGAGGTTGCATTTGAGGCAGCACACGTTCGAGAGGCCTTTAGTCTGTACTATCTGTGGAGCGAACTTCACGCGGCAGTCCACTCTGGCCAACCACACGCGCACCGAGCACAGCGACCAGAGAGACAACAACGACGAGCAGGTCGAGGATCAGCCTCTCAAGTGTCTGAAGTGCAAAAAACCATTTGACCGAAGGCTCCACATGACTGACACGTCTAACCTCAACTTTGTGTCTTTTGTCATAAATGCTTCTAATATgtgtcaaattaatttttggtTATCGCTAGCGTTCTGTATCTGTTTCGTTCACCCAACATCCAAGGTGGATCGTAGCGGGTTCGATGCGCGCTGTTGTGAAGTTGCGGCGTACGAATATAACATCTCGTCACAGCACGTCGCCATGTCAACATCAATTTGCATCACTAACGGCCCCCGGATGCGTCCGTGTCAGCCGTCACACAACTCCTTCACAAATATAAGGAAACATAATTTGACACTCGCTTTGATAGAACATTCCCGGCCGCCGTCGTCGGCGATGATGTTTTTATATCCGACTGTAATAAATTCCTCCGGATACTCGATTCAAAGACGCTCAGATAGAGTGCCgcttgattttattaaaaacatatgcaTCGGTTTTGCGGACCGTCATACGAGTGCCAAACGAGCGCCGAGTATACTTCAACAATCTCCTGATGGAAATATTCATGttcaaAACATTGTGGAGCCATTGAGGGAGTCTAACACCGTTGATGATCTAACTTGTGTAATATCTTATGCATTATTGCGCCCGGTGCCTGCATTAATGCACGGAGAGCGCTAA
Protein Sequence
MLSPHDDDDDNHLCIKCNATIIGLDNYVKHRKQGCRKRKIDSKPELASIDPLEATYNLGADVFFQSLELQSSVKRSPLSRLTPPTPVTKNSIDKKNSLNVASTSRDIPRISPIESNLRGEDWIGGHSLRIGSNEDNQTKLINAVANISGSVKKEPLNAYNITNFSVYKEDNDSEESNVSEEEEEDEIVVDEGSWPPPPNYTGGKWRPASPDQEWDVREEQEQVDRDYDYDAPPPEHTKGKWIPGANERTQIMQTTIQTKGSVQYWCGPCNRRLGSRAIYEKHLKSNLHMRKVLPEQELEFTGSLVSTNNSLVTPRSAGAAMFVSAVYSSPTRRRNKKESKVSIRMNKKKRKRTSCYVQCSGCKTRVKRNLMGKHLISHYHFRKGTVVKNFLYKQLVLNNIDAIVHQAPFQCSPCKFYTNWQTNFMQHWNSEEHRSTISSIEGVYWCSFCKFESETCEEMSAHITSTEHGEVASVINRSMPIIIRKKSVIKCHTCPMVFRYNVEVKHHCRTTGHDLPYSASDIYQEVHRCHHCKKKFKLSISLVAHLKKRHNDSVYFCLLCSKTFNSAVEVKNHRQSTEHRVKRLEVLRERGLLTKDISKKCPYCPQYVVLKNTLELREHIINVHPSIKKKCPKCGKEFIFSQEVSRHIRSNACKLHNPEVPQSSITWKCSQCLFVTDSQAECFFHEVLHTEPSTETTKTNKIIKKYKCPLCPKTFRKPSLRLHLRQHTFERPLVCTICGANFTRQSTLANHTRTEHSDQRDNNDEQVEDQPLKCLKCKKPFDRRLHMTDTSNLNFVSFVINASNMCQINFWLSLAFCICFVHPTSKVDRSGFDARCCEVAAYEYNISSQHVAMSTSICITNGPRMRPCQPSHNSFTNIRKHNLTLALIEHSRPPSSAMMFLYPTVINSSGYSIQRRSDRVPLDFIKNICIGFADRHTSAKRAPSILQQSPDGNIHVQNIVEPLRESNTVDDLTCVISYALLRPVPALMHGER

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00421701;
90% Identity
-
80% Identity
-