Dmel043978.1
Basic Information
- Insect
- Danaus melanippus
- Gene Symbol
- -
- Assembly
- GCA_010014825.1
- Location
- JAAAKD010002395.1:5259-6842[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 4.9 8.9e+02 2.4 1.7 2 23 209 231 208 231 0.86 2 10 0.0001 0.019 17.0 1.3 1 23 237 259 237 259 0.99 3 10 0.0031 0.57 12.4 4.0 1 23 265 288 265 288 0.92 4 10 0.071 13 8.1 0.1 2 20 295 313 294 315 0.93 5 10 1.4e-05 0.0026 19.8 1.1 2 23 337 358 336 358 0.96 6 10 1.5e-06 0.00027 22.9 1.3 1 23 365 387 365 387 0.97 7 10 1.6e-05 0.0029 19.6 0.8 1 23 393 415 393 415 0.97 8 10 1.6e-05 0.003 19.6 1.5 1 23 421 443 421 443 0.95 9 10 9.4e-05 0.017 17.2 4.4 1 23 449 471 449 471 0.98 10 10 1.6e-05 0.0029 19.6 3.8 1 23 477 500 477 500 0.98
Sequence Information
- Coding Sequence
- ATGTCCGAACAAATAGAAACTTATTGCCGGCTGTGTGCTGAACCGACGCCTAAAACCCAGCTCATAGAACCAGAAGAGGATGTAGCTATAACTTCCAAAATACTCGCCAAATTAACGTGGATCAACGTTGATGTGTCTATATCCAACGGCCTTCCGAATACAATTTGTTTCTCCTGCTTCGACCAGCTCGAGAGAACCTGGGCTTTCTTAAACAATGTCAGGTGTGCACAGGACAAATTAAATACGATATTTAAAAAGGATTCCGTggaaaaagttattgaaatcgATTCCAAAAACAATTTGAACTACCAGAATGTTGCTGGGAAACCTCTGGACAAGGATTGGGAGGCAGTTGAAGGTTTTAAATCGGAAATTAAAGTTGAAAACGCTGATATATTACAAGTTATACCGATAACTGATATAAAAGCGGAAGCAGACAGTGAAGAAGATTTTAAACTAAGAATAGATTATGATAGTTTAGATTTAAGTTCGACTGATAGTGAAGCACCCTTAGTAATAACCAAAAAGAACAAGAAATTAAAACGTAAAGTGAGAGAGAACAAGAAAGATGTGAATGAAATCTCCGTAGACTCAATTGTATCATCGTGGGACGAGCAAGGCTGTAGGTGTGCCGAGTGTGATGCTCAATGCAAAAGCATATTATCATTACAACTGCATTCGATCCAAATACATAACAGCTGTTGCGTTTTCAAATGTACAGATTGCTCGAAAGTCGCTAGAGGTTACCGATCATTTATAAGGCACATACGGACGCACAATAGAGATTTAAGACACTGCTGTGAGTACTGCAACGAAGTATTTAGCTCCATATCCAAACTAAAACTACATAAGGTCAAAGAGCACAGATTTGTGTTCAAAACTAAATGCACATCATGCGGTGCCGGTTTTGATACTGTTGAACAACTGAACGAACACAAGGCTCTATTCGTTAAGGATCCGAAGAAGATTAAAATATCTGAAACAATCAAAGAGGAAAGTACCGAAATGAAATGTGATCGTTGTgacaaagtttttaaaacaagagCCAATCTCTTGCAGCATAAGTTACTGCACACCGAGAGGATACGGAATTTTGCATGTCATATATGCGGCAAGATGTTCTTCACTAAGGGCACCCTAGTAACACATATGGTTACTCACGAAGACACAAAGCCTTTTAAATGCGACCACTGTCCCTTAACCTTCCGAGCTAAAGGCAACCTTATATCTCATATATCATTACATTCTGGTCTCAAACCATTCATATGCGAGCAATGCGGTAAAAGCTTCAGAGTTAAACGGCACTTAATGTCACATTCCATAGTCCACACAGATCTAAGGCCATTCGTTTGTGAATACTGCCACAAGGCTTTCCGTTTTAAAACTCGTTTAAATCTCCATCTACGACAGCACACAGGTGTTAAGCCGTACAAATGTGTTTACTGCCAACGAGATTTCACTAACGGATCCAATTATAAGAAACACATGAAGAGACGCCACGGGATCGACACATCATCAAGAATAATGTTCAATAACTCGAATCCCGTTAAAGTTggtggttttaatttaaaggctAATTCATAA
- Protein Sequence
- MSEQIETYCRLCAEPTPKTQLIEPEEDVAITSKILAKLTWINVDVSISNGLPNTICFSCFDQLERTWAFLNNVRCAQDKLNTIFKKDSVEKVIEIDSKNNLNYQNVAGKPLDKDWEAVEGFKSEIKVENADILQVIPITDIKAEADSEEDFKLRIDYDSLDLSSTDSEAPLVITKKNKKLKRKVRENKKDVNEISVDSIVSSWDEQGCRCAECDAQCKSILSLQLHSIQIHNSCCVFKCTDCSKVARGYRSFIRHIRTHNRDLRHCCEYCNEVFSSISKLKLHKVKEHRFVFKTKCTSCGAGFDTVEQLNEHKALFVKDPKKIKISETIKEESTEMKCDRCDKVFKTRANLLQHKLLHTERIRNFACHICGKMFFTKGTLVTHMVTHEDTKPFKCDHCPLTFRAKGNLISHISLHSGLKPFICEQCGKSFRVKRHLMSHSIVHTDLRPFVCEYCHKAFRFKTRLNLHLRQHTGVKPYKCVYCQRDFTNGSNYKKHMKRRHGIDTSSRIMFNNSNPVKVGGFNLKANS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00959622;
- 90% Identity
- iTF_00419209; iTF_00419954; iTF_00421587;
- 80% Identity
- -