Dmel001416.1
Basic Information
- Insect
- Danaus melanippus
- Gene Symbol
- -
- Assembly
- GCA_010014825.1
- Location
- JAAAKD010000076.1:105730-117424[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.016 3 10.1 0.2 1 23 27 49 27 49 0.97 2 11 6.7e-05 0.012 17.7 0.6 1 23 55 77 55 77 0.97 3 11 9.1e-08 1.7e-05 26.7 1.9 1 23 83 105 83 105 0.96 4 11 2.8e-06 0.00051 22.0 3.3 2 23 112 133 111 133 0.96 5 11 0.02 3.8 9.8 1.4 9 23 143 157 142 157 0.94 6 11 5.2e-06 0.00095 21.1 2.1 1 19 230 248 230 252 0.94 7 11 0.0054 0.99 11.7 0.1 3 23 259 280 258 280 0.95 8 11 3e-05 0.0055 18.7 6.0 1 23 326 348 326 348 0.97 9 11 0.061 11 8.3 2.2 3 20 357 374 357 376 0.94 10 11 1.6e-06 0.00029 22.8 5.1 1 23 429 451 429 451 0.98 11 11 2.6e-08 4.7e-06 28.4 1.7 1 23 457 479 457 479 0.97
Sequence Information
- Coding Sequence
- ATGGAGTTAATGATAAAGCAGAGCCTCATAGCTAAGAGCAAGCTGGCAACAATAAAACGCTCTGAGGGGGTGACACACTTCACTTGTGTGGAATGCTCTGCTGAATATGATGATAAAGAGAAGCTTGAACTGCACCTGTTCTCACACTATCATACTTATAGATTCATTTGTGGTGTCTGTGGGACAGGATTAAAGCGGAAGGAACATTTAGACAGACATATGCAGGAACACACAGAGTACCGTCCGCATATCTGCCCAGACTGTGGCAAGGGATTCAAGAGGAAAGAACATCTCAATATACACATGACAATACACAAGGGCGATAAAAATTTGATGTGTTCTCTATGTCAAAAGGcCTTCTACCGCAAGGATCATCTACAGAAGCACTTGCAGACCCATAATAAGAACTTTtatacaattattttagcCTTCTACCGCAAGGATCATCTACAGAAGCACTTGCAGACCCATAATAAGAACTTTGtcaaacaaaattcaattttggAGCCGGATATAGACATCAAGCAAGAGGCGGAGGAATTTGAGGAGTTCAATCCGATCATAACAAGTGTCATCGGTAATGATGAGGCACAGGCCTTCATGGAGACAGATGATCAGAATTCAAGCGAGTCCACCTCCGATCAGAAGGACGTGAAGCCGGAGCCAGTAATCGATGCCTCGAGACCGTTTGTATGTCAGGACTGTGGGAAGAGTTACAAGAGGAAGGATCACCTCAAGATACATAGCTGGACACATATCAAAAGGGAGGTGCTCTGTGGACAGTGTGGAAGAGCTTTCCACACGGCCGACCAGATGCTGGTTCACGTGAACCTGGTCCACATCCGCACACATGAGACCACGGGCGGAGTGGCGCAGCTGAGGGCGCTGCTCGGAGACCAGATCGACGTGGAGGTTCTGAACAATAGCTCGAGCCTGCTGGTGGAGCGCGAGTCGTCGAGTCCAGAGCGCAGGCCCCACGAGTGTCCGGTCTGCCACCGGAAGTTCAAAAGGAAACAACATCTGAAAGTCCACGCGAACGTACACTTCAAACAGACACACACAGTGTGGTGCTCGCTCTGTAACGAAGGTTTCAGCGACAACTCTCAGTTCGAGGGTCACCACTGTCAGTTTACGAACCAGAGCCAGGGCGAGGAGGCGGAGTACGAGGACACGCAGGACAGCCCCCCGCAGGACGCCAAGAAAGAAAACAATCCCATAGACTTCGTGGAGgTGGAGTTGAACGATCCGTCGAACGAGTCCCGCCTGCCTCTCCCCCGCCGCGTGTACGTCTGTAAGTACTGCGGGAAGCCGTTCAAGAGAAAGGATCACTACAAGATACATCTCCACATACACACCGGTATTAAGAGCTTCTTCTGTCCAGACTGTGGGAAAGGTTTCTACCGCAAGGATCACCTCCAAAAGCACATGATAGTTCACGCGAAATTCAAGTTGAAACCCAAAAACAAGAAGGAGGTGCCCGACCTCGTGCCCATAGACACCCTCAAGAAAGAAGTCAAGCCTGAGATAACTATACATGCCCCGTCGAACACCAAGCTTCGCATGCCGCTCCAGATCAAGGTTCCCTACCAGATGGTGATGAGTTTGGACAACGGGGAACAGACAGCGGTCACCATAGACCCCACCGATGatactaacattattatatag
- Protein Sequence
- MELMIKQSLIAKSKLATIKRSEGVTHFTCVECSAEYDDKEKLELHLFSHYHTYRFICGVCGTGLKRKEHLDRHMQEHTEYRPHICPDCGKGFKRKEHLNIHMTIHKGDKNLMCSLCQKAFYRKDHLQKHLQTHNKNFYTIILAFYRKDHLQKHLQTHNKNFVKQNSILEPDIDIKQEAEEFEEFNPIITSVIGNDEAQAFMETDDQNSSESTSDQKDVKPEPVIDASRPFVCQDCGKSYKRKDHLKIHSWTHIKREVLCGQCGRAFHTADQMLVHVNLVHIRTHETTGGVAQLRALLGDQIDVEVLNNSSSLLVERESSSPERRPHECPVCHRKFKRKQHLKVHANVHFKQTHTVWCSLCNEGFSDNSQFEGHHCQFTNQSQGEEAEYEDTQDSPPQDAKKENNPIDFVEVELNDPSNESRLPLPRRVYVCKYCGKPFKRKDHYKIHLHIHTGIKSFFCPDCGKGFYRKDHLQKHMIVHAKFKLKPKNKKEVPDLVPIDTLKKEVKPEITIHAPSNTKLRMPLQIKVPYQMVMSLDNGEQTAVTIDPTDDTNIII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00842874;
- 90% Identity
- iTF_00421539;
- 80% Identity
- -