Basic Information

Insect: Danaus melanippus
Gene Symbol: ham
Assembly: GCA_010014825.1
Location: JAAAKD010000756.1:21937349-21943725[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0086 1.6 11.0 0.0 2 23 51 73 51 73 0.94

2 9 0.00057 0.11 14.7 1.0 1 23 80 103 80 103 0.93

3 9 1.5e-08 2.7e-06 29.2 0.1 1 23 109 132 109 132 0.96

4 9 1.3e-06 0.00023 23.1 1.7 1 23 138 160 138 160 0.95

5 9 4.5e-05 0.0082 18.2 6.1 1 23 166 188 166 188 0.99

6 9 9.1e-05 0.017 17.2 0.4 2 21 196 215 195 216 0.94

7 9 1.1e-08 2e-06 29.6 0.7 1 23 617 639 617 639 0.98

8 9 3.9e-07 7.1e-05 24.7 1.7 1 23 645 668 645 668 0.97

9 9 2.8e-05 0.0052 18.8 4.4 1 23 674 696 674 696 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0086	1.6	11.0	0.0	2	23	51	73	51	73	0.94
2	9	0.00057	0.11	14.7	1.0	1	23	80	103	80	103	0.93
3	9	1.5e-08	2.7e-06	29.2	0.1	1	23	109	132	109	132	0.96
4	9	1.3e-06	0.00023	23.1	1.7	1	23	138	160	138	160	0.95
5	9	4.5e-05	0.0082	18.2	6.1	1	23	166	188	166	188	0.99
6	9	9.1e-05	0.017	17.2	0.4	2	21	196	215	195	216	0.94
7	9	1.1e-08	2e-06	29.6	0.7	1	23	617	639	617	639	0.98
8	9	3.9e-07	7.1e-05	24.7	1.7	1	23	645	668	645	668	0.97
9	9	2.8e-05	0.0052	18.8	4.4	1	23	674	696	674	696	0.98

Sequence Information

Coding Sequence: ATGTTAAACAATGCTCGAGGCGTGGTTGTACTCGTGACTCGTATTAGTTCTGCGAGTGTCAATGAAATATCTCACTTCCGAAGTAGAGAGAGTGCTAGCAGTCATTCTCACCAGCAACAGGACGAAGAAGACAGAGAGGATACAAAACCTCGCTGTTCCTTCTGCGACGAACCATTCCCTAATATTGATGCACTTGACCGTCACTTGATTCAAGCACATGCTCAGCCAGCTTCGGCATATCATTGCGAGCTGTGCAACAGAGCGTACAGTTCCCGGGCACTTCTCCTAAGACACCGGGCGTTAACACATACCGATATCAGGAAATATCCCTGCGAAAATTGTCCTAAGGTATTTACCGATCCTTCCAACCTCCAGCGCCACATCCGCGCGCAGCACGTGGGTGCCCGCAGCCACGCCTGCCCTGAGTGCGGCAAGACCTTCGCCACCAGCTCGGGCCTAAAGCAGCATACACATATTCACTCCAGTGTCAAGCCGTTCCAGTGCAAAGTCTGCTtcaaggCATACACTCAATTCTCGAATTTGTGCAGACACAAACGAATGCACGTTGCGTGCAGAGCATTGGTAGAGTGTGGGAAATGTGGACAATCATTTACGTCGTACGCATCTCTTACCAAGCATAAGAGATTTTGTGACACTGCTTCTGCAACGAACGTTAATCTCAGAGGACAAATTGGTCAAGGACTACCACAGATACCACCTATTCCAAACGTCATGAataatcctaataatacaaaCCCATTCCCCATGTACAGGGGTCCAGCTCTGCCATTACCATATAACACTTTCGCACATTACCCAGCCTTTATCTCCGCTGCTGCTGCCGCAGCTTGCCCTCCAGACTTCTTAAGTCCCCTTCTCTTCAATGTCCAAGGAGCGAGGTTAGCTATGGAGCATGATTTGGCACTTAACGCCAGTTTAATGGCAAAGCAACAACAGGAAGAACGCATGTCAGTAAAAAAGGAAACAGAGAGCATAGATAGTTCATCATCTGtagatatgataaataaaacaaaagaaatgacCAGAGATGAGAAAGATATGGATGTAGACAGAGTAACACCTAAACCTCAAGAACATTATGCAAAACAATCACCACCATCGGCTGAAGAGGCTACTTCAAAACAACGGCCTTCTCCAGTTATGCCACTGTCGACTACTGTTGGACCCTTTGATTTTAcaagaaatgaaacaaaacacaACTCTCTGTAcgatttttctttgaaaaataataacgacACTATAGAAAATAAGTCAATTTCTCCTCAGCCGAAAGATTTGACGAGGAATACTATGTCGAGTGATGGGGAAAAACAATCAAGATATTCTAATTTGGAAGAAGAAACCAAAGAGCAGAATGACCAACCGCTCGACTTATCTGTTACTCGAAAACAACGAGACAAGGACTCAGACTTAGAAAATGATGATCATTCCTTTCGAAATTCTTCGGTAAAATCTTATTCACCCGCGGAAAGTCCTGTTGATAGAGAGAATAAGACTCCGGAAAATGAGACAACTGATGTTGATGTGGAAGCTGTTGAACCCAAAAGAGAGGATTCCCCAGTATCAATGATGTCTCCTCCCTTAGCATTTCCAATGGCTGTTCACGCTCAGCACAATAACAGTCTCATGAATGCTATGTACCCACCACGCTTTACACGCTTCCATTCGACTTCTGACTCCATACTTAATTCACAGCACTCACCATACGTTCCGAGTccgtttaattttttatcgcCACTTCTCGGCACTGATGGCCCTGACAGGCAAGCAAGTGCCTACGCGAAATTTCGTGAACTTAGCGCTGGATCCGGCAAGTTGCGAGATCGCTATGCTTGCAAATTTTGCGGAAAAGTATTTCCGCGAAGTGCTAACTTAACGCGTCATTTACGTACGCACACCGGCGAGCAACCATACAAGTGCAAATATTGTGAGCGTTCCTTTTCCATATCCTCTAATTTACAGCGACACGTAAGAAACATTCATAACAAAGAGAGGCCGTTTAGATGTCAGTTATGCGATAGATGTTTCGGGCAGCAGACTAACCTAGATCGACACCTTAAGAAACATGAGGCGGAAGGTGGTGATTCACCAAGTTCCGGGGATACTGAACACGACGCGTGTTTCGATGATATCCGATCTTTCATGGGGAAGGTGACCTGTTCTCCTGGAGCAGGATCCCCATCAGCGACGTCTCCTCACCCATCTCACGCCCCACATCCTCCACATCGACCTTCAGCGCTTTCCATTTCCACCTAG
Protein Sequence: MLNNARGVVVLVTRISSASVNEISHFRSRESASSHSHQQQDEEDREDTKPRCSFCDEPFPNIDALDRHLIQAHAQPASAYHCELCNRAYSSRALLLRHRALTHTDIRKYPCENCPKVFTDPSNLQRHIRAQHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCKVCFKAYTQFSNLCRHKRMHVACRALVECGKCGQSFTSYASLTKHKRFCDTASATNVNLRGQIGQGLPQIPPIPNVMNNPNNTNPFPMYRGPALPLPYNTFAHYPAFISAAAAAACPPDFLSPLLFNVQGARLAMEHDLALNASLMAKQQQEERMSVKKETESIDSSSSVDMINKTKEMTRDEKDMDVDRVTPKPQEHYAKQSPPSAEEATSKQRPSPVMPLSTTVGPFDFTRNETKHNSLYDFSLKNNNDTIENKSISPQPKDLTRNTMSSDGEKQSRYSNLEEETKEQNDQPLDLSVTRKQRDKDSDLENDDHSFRNSSVKSYSPAESPVDRENKTPENETTDVDVEAVEPKREDSPVSMMSPPLAFPMAVHAQHNNSLMNAMYPPRFTRFHSTSDSILNSQHSPYVPSPFNFLSPLLGTDGPDRQASAYAKFRELSAGSGKLRDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFRCQLCDRCFGQQTNLDRHLKKHEAEGGDSPSSGDTEHDACFDDIRSFMGKVTCSPGAGSPSATSPHPSHAPHPPHRPSALSIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00461745;
90% Identity: iTF_00419910; iTF_00421532; iTF_00419166;
80% Identity: -