Dmel028127.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Danaus melanippus
Gene Symbol
-
Assembly
GCA_010014825.1
Location
JAAAKD010000756.1:28618187-28626559[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 8.7e-05 0.016 17.3 0.1 3 23 128 148 127 148 0.97
2 17 7.9e-07 0.00015 23.7 1.2 1 23 154 176 154 176 0.99
3 17 4.9e-06 0.0009 21.2 2.7 1 23 182 204 182 204 0.99
4 17 8.7e-06 0.0016 20.4 1.6 1 23 219 241 219 241 0.98
5 17 4.5e-05 0.0083 18.2 3.1 1 23 256 278 256 278 0.98
6 17 3.1e-07 5.8e-05 25.0 1.5 1 23 293 315 293 315 0.99
7 17 0.00014 0.026 16.7 2.8 1 23 321 343 321 343 0.98
8 17 4.8e-06 0.00088 21.3 2.0 1 23 349 371 349 371 0.99
9 17 0.032 5.8 9.2 1.8 1 23 378 400 378 400 0.98
10 17 5.3e-07 9.8e-05 24.3 2.3 1 23 406 428 406 428 0.99
11 17 0.037 6.8 9.0 1.8 1 23 435 457 435 457 0.98
12 17 2.2e-06 0.0004 22.3 1.5 1 23 463 485 463 485 0.99
13 17 0.00041 0.076 15.2 0.7 1 23 492 514 492 514 0.99
14 17 2.4e-06 0.00044 22.2 1.9 1 23 520 542 520 542 0.98
15 17 0.0018 0.32 13.2 0.3 1 20 548 567 548 570 0.93
16 17 3.3e-05 0.006 18.6 1.3 2 23 577 598 576 598 0.96
17 17 3.1e-06 0.00057 21.9 1.4 1 23 604 627 604 627 0.97

Sequence Information

Coding Sequence
ATGTTCGAACAACAAATCAAGGCCGAGCCCATGAGtttttacACACATTCACATGTAAATACTGGACCCCCAACAATAATGCGCTCGGATTCCGGCCATGGCATAATCAGTATGAATCCACACCATCCCCAGGAGGACTCCAAGGACAGTCTCATACAACAACAAGTACAACACCAACAAGAGCTGATGGAACAGCACCAACAGGACTTGCAGCACGATGATGATGTTgataatTTAAGCTTCAAAGGCATGGATGATGAGGGTGTTGAATTGGACATGGATGGCAGACAATGTTCTCAGGGCATGGTCGAAATGGGATCCGTTCAAACCAAAATGGAAGTCTCAAACGGTGTTGGGATGCCGAGATCGAAACCACAAGCTtgtaaaGTATGTGGTAAAGTGTTATCGTCTGCATCGTCATATTATGTTCACATGAAACTCCATTCTGGCAACAAACCTTTTCAATGCACGGTATGCGACGCTGCGTTTTGTCGCAAGCCTTATCTTGAAGTGCACATGCGCACGCACACCGGCGAGCGCCCCTTCCAGTGCGATCTGTGCTTAAAACGCTTCACACAGAAGTCCAGCCTCAACACGCACAAGCGCGTCCACACGGATGAGCACATGCGAGCCTTGATGGTGAAGGATCGTCCCTACCAGTGTGAGGTCTGTCTGATGCGCTTCACTCAGAGCTCCAGCCTCAACAGACACAAGAAAATACACACGGAGGAGCACAGACGAGCCCTGTTAGAAAAAGTGCGGCCGTACCAGTGCCACATCTGTTTTATGCGCTTCACTCAGAAGTCCAGCCTGGGCCGACACGGAAAGATACACACCGAGGAGCACATCCAATCGCTGATCAACAAAGTGCGCCCCTATCAATGCGACATCTGTGACAAGCGGTTCACTCAGAAGTCCAGCCTTGGCACTCATAAACGTATACACACCGGCGAGCGGCCCTTCCAGTGCACCGTCTGCCTCAAGTCCTTCACGCAGAAGTGCGCGCTCAATTTGCACGAAAAGATACATACGGGCGAGCGGCCGTATCAGTGCGACGCCTGTCTCAAGCGCTTCACGCAGAAGTCCAGCCTCAATATACATAGACGGACACACACAGTCCAGGGGAGACCGTTCCAGTGCCTGTCGTGCCCGGCCGCCTTCACCTGCAAGCAATATCTGGAGATACACACCCGCACGCACACAGGCGAGCGGCCGTATCAGTGCGACATCTGCCTCAAGCGGTTCACTCAGAAATCCAGTTTGAACATCCACAAACGGACGCACTCAGTTCAGGGGCGGCCGTTCCAGTGTCTCCAGTGCCCGGCCGCCTTCACCTGCAAGCAGTACCTCGAGATACACAACCGCACGCACACCGGCGAGCGCCCCTACCAGTGTGATGTCTGCCTCAAGAGATTCGCGCAAAAGTCTACACTCAATATACACAAAAGAACGCACACAGTGCAAGGGAGGCCGTATCAGTGCATGGAGTGCCCGGCGGCGTTCACATGCAAGCCGTACTTGGAAATACACATGCGCACACACACTGGCGAGCGGCCCTTCGAGTGCGATGTCTGTTACAAACGCTTCACCCAGAAATCAACACTCAACATTCACAAGCGAATTCATACCGgcGAACGTCCATACGCATGTGATATTTGCCAAAAACGATTCGCAGTTAAGAGCTACGTAACAGCGCACCGATGGTCCCACGTGGCGGACAAACCTCTGAACTGCGAGCGATGTTCCATGACGTTCACCTCCAAGTCCCAGTTCGCCCTCCACATCCGGACCCACGCCAGTGGACCCTGCTACGAGTGTAGCGTCTGCGGCCGCACCTTCGTCAGGGACAGTTATCTCATACGTCACCACAACCGCGTACACCGTGAGAACCACAGCAACATATCAGCGAACAGCATCGGCACAATCAACAGCGTGGCCACCAACACCAACTCCAACAACGGCAACTACGACTCGCCAGGCGTCTGTGACCTCAGTTTCGTGCCGATGGTAAATCGCTACATGACGTCTCAAGGCACGCAGGTTTCTATGCAGGACACAAAAATGTCCGCCATGTCGCCGCAGTCGATCGCGTCAATATCGTCGCCGCCGCCCCCGCACACTCCCACGCCCCAGCCGCAGATGTCCATGCGACTGTCAGATTGA
Protein Sequence
MFEQQIKAEPMSFYTHSHVNTGPPTIMRSDSGHGIISMNPHHPQEDSKDSLIQQQVQHQQELMEQHQQDLQHDDDVDNLSFKGMDDEGVELDMDGRQCSQGMVEMGSVQTKMEVSNGVGMPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHMRALMVKDRPYQCEVCLMRFTQSSSLNRHKKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCDICDKRFTQKSSLGTHKRIHTGERPFQCTVCLKSFTQKCALNLHEKIHTGERPYQCDACLKRFTQKSSLNIHRRTHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCMECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCERCSMTFTSKSQFALHIRTHASGPCYECSVCGRTFVRDSYLIRHHNRVHRENHSNISANSIGTINSVATNTNSNNGNYDSPGVCDLSFVPMVNRYMTSQGTQVSMQDTKMSAMSPQSIASISSPPPPHTPTPQPQMSMRLSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00824939;
90% Identity
iTF_01034828;
80% Identity
-