Basic Information

Insect: Cynegetis impunctata
Gene Symbol: topi
Assembly: GCA_030704885.1
Location: JARQZK010005334.1:12180-19677[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0025 0.75 12.5 2.1 2 21 128 147 127 148 0.94

2 14 2.2e-05 0.0067 19.0 0.2 1 20 173 192 173 193 0.96

3 14 0.027 8.1 9.3 2.0 3 23 203 223 202 223 0.95

4 14 0.0093 2.8 10.7 0.3 2 20 242 260 241 262 0.91

5 14 4.8e-05 0.014 17.9 0.6 2 23 319 340 318 340 0.97

6 14 2.1 6.3e+02 3.3 0.1 1 20 346 365 346 367 0.85

7 14 0.0027 0.81 12.4 3.4 2 22 383 403 382 406 0.88

8 14 0.23 67 6.4 0.1 1 23 535 558 535 558 0.96

9 14 0.14 43 7.0 0.9 1 23 562 584 562 584 0.91

10 14 8.4e-07 0.00025 23.5 2.4 1 23 590 612 590 612 0.98

11 14 0.023 6.9 9.5 0.2 1 23 618 643 618 643 0.96

12 14 1 3.1e+02 4.3 2.5 1 23 649 671 649 671 0.85

13 14 5.5e-05 0.017 17.7 1.6 3 23 679 699 677 699 0.97

14 14 2.7e-06 0.00082 21.8 0.9 1 23 705 728 705 728 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0025	0.75	12.5	2.1	2	21	128	147	127	148	0.94
2	14	2.2e-05	0.0067	19.0	0.2	1	20	173	192	173	193	0.96
3	14	0.027	8.1	9.3	2.0	3	23	203	223	202	223	0.95
4	14	0.0093	2.8	10.7	0.3	2	20	242	260	241	262	0.91
5	14	4.8e-05	0.014	17.9	0.6	2	23	319	340	318	340	0.97
6	14	2.1	6.3e+02	3.3	0.1	1	20	346	365	346	367	0.85
7	14	0.0027	0.81	12.4	3.4	2	22	383	403	382	406	0.88
8	14	0.23	67	6.4	0.1	1	23	535	558	535	558	0.96
9	14	0.14	43	7.0	0.9	1	23	562	584	562	584	0.91
10	14	8.4e-07	0.00025	23.5	2.4	1	23	590	612	590	612	0.98
11	14	0.023	6.9	9.5	0.2	1	23	618	643	618	643	0.96
12	14	1	3.1e+02	4.3	2.5	1	23	649	671	649	671	0.85
13	14	5.5e-05	0.017	17.7	1.6	3	23	679	699	677	699	0.97
14	14	2.7e-06	0.00082	21.8	0.9	1	23	705	728	705	728	0.98

Sequence Information

Coding Sequence: ATGGATAATTccgataatttcatttttaaagtATATAAGATCGATCAAAACGGAATGATAATTTCAGTAGTTCAATATGAACAGGATTTTTATACAGGCGATGTTGTTTCCAAAGTACCCATTTCTTCTGATGTTGTTAGTTTCATTTTAGATTCAGATTTGAATAAACTGAATTTGAGTTTTAACAATTTCGAGTGTGGTGATGAGGAAGATCCAAATGTGAGTTTTGTCAAATTAGAAAATTTCAGTTCAGCTTCAAATCAAGCTTCCGATTCCAATGATTCTTGCCCTGTAAATAGTGGATCCTATGGTAAGAGTAGCATATCTCCTTGCTTTTTACACCAGAATCCAAAACTTTTACTCAATATTCCCACAATGATAAGATGTCAAAATTGTGAAACTAATTTTCCTACGAAATATCAGTATCAAAGACATCAGTGCGAATTCAATGCAGAGAAAGTAGTTTTGAAGCCAAATGCTGATCTGAAGGACATCAACAAAGGCGTGAGAATCAAATATGATTGTTATGTATGTGGAAAACAATTCGttagtaaaaataatttggaacGTCATCAAGTTTGTCATGATAACttgaaagaaaatatatgtGAGCATTGTAGTAAACAATTTGTGAGCGAAAATAGGTTGAGAATCCATAAAGAAAATCATTGCAAAAAAGCAGGCGATATATCAAAGTTTTATCGTAGTGATGTCGCTGTTTGGAAGTGTAAAAAGTGCCATGAAGTATTCTCGTCTATAAGTTCTGCAAATGTTCATGTGGACTCCTGTAAAGAATTTGTATTTCTATATGATCCTAAGGATGAAAATTCTACTAACAGTTTAGAATTTCTCAAACAAGAAATATCGAATGTAGTATCCGTCATTGATGATGGTACAAATTCTAAAGCAGTAGATAATaattacattgaaaaaattttaacagaGATACTTTTACAATGTGAATTCTGCAACAGAACTTACGCAGACAAAGGTTTATTGCTATTACATCAAAGAAAACATTCAACTGATAAGAATTATGAATGCGTGAATTGCAACAGCACATTTGAATCATATGCAATGGCTGCTCAGcattggttgaaaatttgttcagaAACTGCAAATATGTTTTACTTACCTAAATTAACTTATTGTGAATATTGTGATCGTACTTTTAAATCACATGAACTACTTTATactcataaaattaaaaaaaagcatTACACAGTTAAAATACACAAGAATAATGGTGAGTTGAATACTGAGACTTCACAAGAAAAGTCTGTTGATAGTAACGATGCCATAAATAAACTCATTGAAGATGTGCTGATAACTCTTGATAGACCTATCAGTAAAATTAATCAGGTTTTAAAACCAGAATTATATAACTCTAATAGGGAAAATTCATCTGAAAATCCTATGAAAGATAAAATGGAAACAGAGATGGTGTTAGATAATTCTCACACTGAAAATGTTGATGAATCTAATCCAGGTAATCTTTCATCAAATGAACCTGAGAAAAAACAAAGAGGAAGAAAGCGAAAATGGTCAAAGCAAGGAATCAAAAGTAAGAGGCTCCATAATATAACTGATCAGGGATACAAGTATCAATGTGAACGATGTCCCCTTGTCTGGGATAACGTTAATGATTTGGAAAAGCATAGAGAAAGAGAGCATGCAGCAAGTTTTAGCTGTGAAGACTGTGGTCAAATTCTGCATAGTGCTAAAGCATTACTCATCCATTGTCGTGCCCATAAATGCTTGAAACCTTATGTTTGCGATACTTGTGGCCGCAGCTATTCCCAAACTTCCCACTTGTGGCAACATATGAGATTTCATCAGGGTATAAAACCATTTGCATGTCCCCATGAGGGTTGTGAAGCAAGGTATACAATACGGCCAGATTTGAAGGATCACATACGAAAAGTTCATACTCGTGAAAGACCCTTTAAGTGTGCAGTATGCAGTAAATGTTTTCTGACAGGTTCTGTATATTATCAGCATCGTTTAATTCATACTAATGACCGAAGATATGGATGTGATGTTTGCCATAAAAGATTTTTTCGAGCCGATGCTCTGAATAACCACAAAAGAATCCACACCGATGAGCGTCCTTATCCTTGCACAGTTTGCGGAAGAGAATTCAGACAGAAGGGGGACCGCAACAAGCATCTGCGTACTCAACATCCTGACGCCATAATCCAGTAA
Protein Sequence: MDNSDNFIFKVYKIDQNGMIISVVQYEQDFYTGDVVSKVPISSDVVSFILDSDLNKLNLSFNNFECGDEEDPNVSFVKLENFSSASNQASDSNDSCPVNSGSYGKSSISPCFLHQNPKLLLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVLKPNADLKDINKGVRIKYDCYVCGKQFVSKNNLERHQVCHDNLKENICEHCSKQFVSENRLRIHKENHCKKAGDISKFYRSDVAVWKCKKCHEVFSSISSANVHVDSCKEFVFLYDPKDENSTNSLEFLKQEISNVVSVIDDGTNSKAVDNNYIEKILTEILLQCEFCNRTYADKGLLLLHQRKHSTDKNYECVNCNSTFESYAMAAQHWLKICSETANMFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTVKIHKNNGELNTETSQEKSVDSNDAINKLIEDVLITLDRPISKINQVLKPELYNSNRENSSENPMKDKMETEMVLDNSHTENVDESNPGNLSSNEPEKKQRGRKRKWSKQGIKSKRLHNITDQGYKYQCERCPLVWDNVNDLEKHREREHAASFSCEDCGQILHSAKALLIHCRAHKCLKPYVCDTCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCAVCSKCFLTGSVYYQHRLIHTNDRRYGCDVCHKRFFRADALNNHKRIHTDERPYPCTVCGREFRQKGDRNKHLRTQHPDAIIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -