Basic Information

Insect: Cynaeus angustus
Gene Symbol: ZFX
Assembly: GCA_030157275.1
Location: CM058060.1:27644027-27645480[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 5.3 4.3e+02 2.0 0.3 1 14 55 68 55 72 0.82

2 12 0.00079 0.065 14.0 4.7 3 23 144 164 143 164 0.99

3 12 4.9e-05 0.004 17.8 3.3 1 23 170 192 170 192 0.98

4 12 9.9e-06 0.0008 20.0 2.0 1 23 198 220 198 220 0.99

5 12 1.4e-05 0.0011 19.6 0.1 1 23 226 248 226 248 0.98

6 12 0.0021 0.17 12.7 0.6 1 23 255 277 255 277 0.98

7 12 9.2e-05 0.0075 17.0 0.6 1 23 283 306 283 306 0.90

8 12 6.6e-05 0.0054 17.4 5.9 1 23 312 335 312 335 0.95

9 12 0.00023 0.019 15.7 0.1 2 23 345 366 345 366 0.97

10 12 6.7e-06 0.00055 20.6 0.7 1 23 372 394 372 394 0.98

11 12 4.9e-06 0.0004 21.0 1.1 1 23 400 422 400 422 0.95

12 12 1.6e-08 1.3e-06 28.9 0.5 1 23 428 450 428 450 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	5.3	4.3e+02	2.0	0.3	1	14	55	68	55	72	0.82
2	12	0.00079	0.065	14.0	4.7	3	23	144	164	143	164	0.99
3	12	4.9e-05	0.004	17.8	3.3	1	23	170	192	170	192	0.98
4	12	9.9e-06	0.0008	20.0	2.0	1	23	198	220	198	220	0.99
5	12	1.4e-05	0.0011	19.6	0.1	1	23	226	248	226	248	0.98
6	12	0.0021	0.17	12.7	0.6	1	23	255	277	255	277	0.98
7	12	9.2e-05	0.0075	17.0	0.6	1	23	283	306	283	306	0.90
8	12	6.6e-05	0.0054	17.4	5.9	1	23	312	335	312	335	0.95
9	12	0.00023	0.019	15.7	0.1	2	23	345	366	345	366	0.97
10	12	6.7e-06	0.00055	20.6	0.7	1	23	372	394	372	394	0.98
11	12	4.9e-06	0.0004	21.0	1.1	1	23	400	422	400	422	0.95
12	12	1.6e-08	1.3e-06	28.9	0.5	1	23	428	450	428	450	0.99

Sequence Information

Coding Sequence: ATGGAGGCTTTCACCGAATACGAAAACGTGCAAATCGACGAAGTTTGCAGAATCTGTCTTACAAAAAAAGAGCAAATGAATCTAATCTACGAAGCGGGCTTGGCCGACATGCTCTTAGAATGTGCTTCTGTTCAGgttacCCCCGAAAACGGCCTCTTTAATTTCGTCTGCAATCAGTGCCAGAACGAGGTTAGCCGTTGGTATGTTTTTAAACAGCAAGTGGTTCGGTCCTTTGAAATCGGCAAGTGGTTGTTGAGCAAGAAGAAGGAAAAAACAGACTACGGGATAGATTCAGAGTTCCCCAACCGTGAAAGTGAAGTTCTAGAGAGTGTGGAAAGGCTGGATGACCTTCTCGAGAAGCCGATTTTCGAAGGGGTGAACCCTGAAGAAGACACGGCGAAGAAAAAGAAGGCACCGGAGGACTTACTgtgtaaaatttgcaataaacaGTGCAGTTCGACGAACTCGTATAACCGTCACATTAAAACGCACGATGACACCAGACCTTTTGTTTGTTGCAAGTGCGACAAACCTTTCAAAACTTCACAGGTTCTCTCGGAGCATATGAAGCGACACTACGACGATAGACGCTACCAATGTGACCTTTGCAGCAGGAAGTTCTACTCTAAGGCTAGTTTAAACGACCACACGAGGAGTCACACCGGGGAAAAACCTTTCAAATGTGAAGTTTGCGGCCGGAGTTTCGGCACCAAGGCTATTTTAAGACAGCACATGGCGGTCCACACAGTACGAGAGAAAAAGTTTCAATGCAAAATTTGCAACAAGTTCCTCCTCTCCGCCGGCAGCTTAGAAACCCACGTGAAAAAACACAGCGGTATCAAACCCTTCCCTTGTTCGGGTTGCGATAAGAGGTTCTTCACCAAGGAGGCGATGCAACGCCATTTTAGTGCCATCCACGACACCGATAATAACTTCCTTTGTAACGTCTGCTCGAAAGTGTGTTCCACAAAGGTCCACCTCAACAATCACATGAAAAAGAAACACCTGGGGCTCGGAAAACCACTGAACGCCGTCTGTGCAGAGTGTGGGAAACAGTGTGGTTCCGCCGCCGAGTTGAAAGTCCACGTACGAGTCCACACCGGCGAAAGACCCTTCGTTTGTGACATTTGCAACAAAAGGTTCATCGCCAAAGGAAATCTAAACTCGCACAAGCAGAGACACACGGGGAAAAAACCTTTCCTCTGTAACCACTGCGGGAAGGCCTTCGGGGAAAAGTCCACGCTGAAAGTCCACGAAAGGATACACACCGGCGAGCACCCGTACAAATGTGAAATTTGTGATAAAGCGTATGTACAAAGTAGCGCGTTAAGGACGCACATGAAGACGCATTGGAAacaatag
Protein Sequence: MEAFTEYENVQIDEVCRICLTKKEQMNLIYEAGLADMLLECASVQVTPENGLFNFVCNQCQNEVSRWYVFKQQVVRSFEIGKWLLSKKKEKTDYGIDSEFPNRESEVLESVERLDDLLEKPIFEGVNPEEDTAKKKKAPEDLLCKICNKQCSSTNSYNRHIKTHDDTRPFVCCKCDKPFKTSQVLSEHMKRHYDDRRYQCDLCSRKFYSKASLNDHTRSHTGEKPFKCEVCGRSFGTKAILRQHMAVHTVREKKFQCKICNKFLLSAGSLETHVKKHSGIKPFPCSGCDKRFFTKEAMQRHFSAIHDTDNNFLCNVCSKVCSTKVHLNNHMKKKHLGLGKPLNAVCAECGKQCGSAAELKVHVRVHTGERPFVCDICNKRFIAKGNLNSHKQRHTGKKPFLCNHCGKAFGEKSTLKVHERIHTGEHPYKCEICDKAYVQSSALRTHMKTHWKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00753204;
90% Identity: iTF_00753204;
80% Identity: -