Basic Information

Gene Symbol
-
Assembly
GCA_963942595.1
Location
OZ012706.1:11204375-11206987[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 8.4e-06 0.0017 20.1 0.6 1 23 350 372 350 372 0.99
2 15 0.32 64 5.7 5.6 1 23 378 401 378 401 0.97
3 15 4.3e-05 0.0086 17.9 0.8 2 23 497 518 496 518 0.97
4 15 4.3e-06 0.00087 21.1 1.6 1 23 524 546 524 546 0.98
5 15 0.00014 0.028 16.3 0.5 1 23 552 574 552 574 0.97
6 15 4e-06 0.00081 21.1 1.3 1 23 589 611 589 611 0.98
7 15 7.5e-06 0.0015 20.3 1.2 3 23 619 639 617 639 0.98
8 15 7.6e-06 0.0015 20.3 2.0 1 23 645 667 645 667 0.98
9 15 0.0075 1.5 10.9 0.5 1 23 673 695 673 695 0.98
10 15 7e-06 0.0014 20.4 0.3 1 23 701 724 701 724 0.94
11 15 2.1e-05 0.0042 18.9 1.3 1 23 730 752 730 752 0.98
12 15 0.00045 0.091 14.7 4.7 1 23 758 780 758 780 0.98
13 15 6.8e-06 0.0014 20.4 0.2 1 23 786 809 786 809 0.96
14 15 5.5e-06 0.0011 20.7 0.9 1 23 815 837 815 837 0.97
15 15 4e-06 0.00081 21.2 4.5 1 23 843 865 843 865 0.99

Sequence Information

Coding Sequence
ATGGATACCGTTACGACAATGAGCAACGAATGGATCCCTACAAAGATTTTGGTAGATCGAGAGGGACCCGTCGTGCTCGATAATCCTTTTGCCTTAGTCAAGCATGATAACAACTTTGTAGGCGAAGACAGAAAGAAGGAAATAAAcagaaattctgaagaaaaggaaaaaattataattccCAGTAGAGCTATAGATTTCATGGATATCAAGACTGAAACTACGATTAACAGACCTCTGTGCTGTATCTCACCGATGAGAATAAATCATAGAGCTCAAATAGATGTCGTCGACATGCAGGATGAAGAATCTACCGTCTACAAGCATATGTTGATTTACGAGGAGCAATACTCAAAATTTGTCATCCTCAGAGCACTCAAGAGCAAAGAAGCGAGGGAAGTCGCAGAAGAGCTGGTTGAAATAGTTACTACGATCGGAGCACCACGAATAATTCAAAGCGGAAACGGTAGGATCTATGCGGAACAAGTTGTACGAGAGATTCGTGTTCTCCTGAGAGATTTTTGCGTTGTTCACGGCGATGCCACGAAGAACGGAGAAGAACGCCGCGATTTCAAGAGATCGCTGAAATCGTGGATGGCGAAAAATCCTGGAAGACAATGGCACGACGGTCTGAAGATTATTCAAGTGTCGGAGAATACAACGGGAAACGCACGTATCGGCAAAGTTCCCAGTCAACTGTTTTTCGGGAGAAATATTTGTGAAGATCTGCGTAGAACGATAGGTGGCAAGGGATCGACGGGAAACGTGAGCACGGAGGATGCCTCGGCTTCGGTGAACCTCAAAGAGCGTGGCTCTATCTTCAACGATCGAAATCGAAATCCTCTCCCGGTTCCTATCGGTGAAATACGCGAGAAGGACGATAAAGAATACGACAGTGACTCTCGAGTCATCGATTGCAGAGAGATTGAAGtgagaggaaacgaaaaaacttTGAGTTTCGGAAACATTAAGAGCGAATTGTCGATAGCAACGGAAAATGACGTAATCGTTAATTCGAACGATGCTGATGATAGcgaaaaaaagaattttcgaTGTAAAATATGTCCAAAGCAGTACGCGGGACTGGGTTATTTGAGAAATCACATGAAAACGCACACGAGAATCGGAAATTTCGAATGCACGATTTGCTGTAAATCGTTTCGTCTATCGACTCGGTACGACAAGCACATGCAGAGATTTCACGACGAGCAAGACACAAATAAGAGTATTGAGACTCGCGATCGCCTGAACGAGGCGGAATACGACGATGGCAATAGCGAGAAAGATGTTGGGTGCAGTCCGAAGAAAATTCAACGAATAGAAGAAGAATGTACGGAGATCAAGACGGAGTTGGACAATCCTAAGAAGGCGCCGTCCTTGTTAACGTCGATCAGAAGTTCaggaaaaaaaacttcaaaaagaTCGCATTCCTTGGCCAGAAGAAAGGTAAACCATTCCTCAACAAAATTAAACAGAAGTGCCCGGCTGGAATGCGCGTATTGCAAACAAAAATTCAACTTCCCGAGTGTCTTGAAGAGACACATACGTTCGCATACGAACGAGAGACCCTACGTTTGTCAAGTGTGCAACAAAAGTTTTAAGCAACTTGGACACCTGAGTCAGCATGCGCTTACGCACACCGACTATCGCTCCTTCAACTGCACAATTTGCGGAATAAAATTTGAGTCGCTCGACTCGCTGAAGCTTCATTCTCAGTCGCACAAGGACAAAACGCTTTCTCATTCAAAGAATCCTTATCGTCTGTTCGAATGCGACAGTTGCAAGAAGGTTTTTACTACCAAAAGCGTTTTGGAGCGTCACATATTCACGCACAGTCACGAACGTAAATTCGGTTGCAAGGTTTGCGGTAAAAGATTCAAGCAAGCCGGTCACGTAAAGTCTCACATGCTGGTGCACACGGGCGAACGAAATTTCGAGTGTACTATTTGCACGAAGCGCTTCAGCCTCTCGAATTCTCTTAAGAAACACATGTACGTGCACAACGGAGAAAAACCATATCAGTGCGACGTATGCGGCTCTAGATTCCTCGAGAAACGTAATCTAAACGGTCATCTCACGACTCACACCAACGAACGACCGTTTTCCTGTAAAATTTGCGGGAAACGTTATACTCTCGCGGATACGCTGAGGCGTCACATAAGCGCTGCTCACGAGGATGGCCGTACTTATCAGTGCGAAATTTGCGCAAAAATGTTCAAACAGCTGGCGCATCTGTCGGTTCACAAAAAAGTTCACAACGACGAGAGGCCCTTTCAGTGTCATCTTTGTGAGAAAAATTTTAAGCACAAGAACGTACTAAAATCTCATCTGGCGATTCACGCTAACGTCAGACCTTTCGAGTGTGACGTTTGCAAAGCGACTTTCGTGAGAAAAACTAATCTTCAGACTCACATCGCCTCGGCTCACATGAACGAGCGTCCTTACGTATGTACGATTTGCAATAAACGCTTCAAGCAAATCAGTCATCTCAATGGGCATATAGTCGTTCACAGCAACTCGATGCCTTATCAGTGCGACTTTTGCGATCGTCGCTGTAACAGACTCGATAATTTGAAAAAACATATGAGACTGCACTCGAAAAACAAGGAATAA
Protein Sequence
MDTVTTMSNEWIPTKILVDREGPVVLDNPFALVKHDNNFVGEDRKKEINRNSEEKEKIIIPSRAIDFMDIKTETTINRPLCCISPMRINHRAQIDVVDMQDEESTVYKHMLIYEEQYSKFVILRALKSKEAREVAEELVEIVTTIGAPRIIQSGNGRIYAEQVVREIRVLLRDFCVVHGDATKNGEERRDFKRSLKSWMAKNPGRQWHDGLKIIQVSENTTGNARIGKVPSQLFFGRNICEDLRRTIGGKGSTGNVSTEDASASVNLKERGSIFNDRNRNPLPVPIGEIREKDDKEYDSDSRVIDCREIEVRGNEKTLSFGNIKSELSIATENDVIVNSNDADDSEKKNFRCKICPKQYAGLGYLRNHMKTHTRIGNFECTICCKSFRLSTRYDKHMQRFHDEQDTNKSIETRDRLNEAEYDDGNSEKDVGCSPKKIQRIEEECTEIKTELDNPKKAPSLLTSIRSSGKKTSKRSHSLARRKVNHSSTKLNRSARLECAYCKQKFNFPSVLKRHIRSHTNERPYVCQVCNKSFKQLGHLSQHALTHTDYRSFNCTICGIKFESLDSLKLHSQSHKDKTLSHSKNPYRLFECDSCKKVFTTKSVLERHIFTHSHERKFGCKVCGKRFKQAGHVKSHMLVHTGERNFECTICTKRFSLSNSLKKHMYVHNGEKPYQCDVCGSRFLEKRNLNGHLTTHTNERPFSCKICGKRYTLADTLRRHISAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHIASAHMNERPYVCTICNKRFKQISHLNGHIVVHSNSMPYQCDFCDRRCNRLDNLKKHMRLHSKNKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-